Escherichia coli K-12 MG1655: b2688 Help Entry b2688             CDS       T00007                                  Symbol gshA Name (RefSeq) glutamate--cysteine ligase   KO K01919   glutamate--cysteine ligase [EC:6.3.2.2] Organism eco  Escherichia coli K-12 MG1655 Pathway eco00270   Cysteine and methionine metabolism eco00480   Glutathione metabolism eco01100   Metabolic pathways eco01240   Biosynthesis of cofactors Module eco_M00118   Glutathione biosynthesis, glutamate => glutathione Brite KEGG Orthology (KO) [BR:eco00001]  09100 Metabolism   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     b2688 (gshA)   09106 Metabolism of other amino acids    00480 Glutathione metabolism     b2688 (gshA) Enzymes [BR:eco01000]  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.2  Acid-D-amino-acid ligases (peptide synthases)     6.3.2.2  glutamate---cysteine ligase      b2688 (gshA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Glu_cys_ligase Motif Other DBs NCBI-GeneID:  944881 NCBI-ProteinID:  NP_417173 Pasteur:  gshA RegulonDB:  RDBECOLIGNC00411 ECOCYC:  EG10418 ASAP:  ABE-0008845 UniProt:  P0A6W9 Structure PDBPDBj LinkDB All DBs Position complement(2814883..2816439) Genome browser AA seq 518 aa AA seqDB search MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD FAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYG TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGY FRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALA DAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTL DSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL EILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA NT seq 1557 nt NT seq  +upstreamnt  +downstreamnt ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatcctcaggcgttaaag gggatacagcgtgggctggagcgcgaaactttgcgtgttaatgctgatggcacactggca acaacaggtcatcctgaagcattaggttccgcactgacgcacaaatggattactaccgat tttgcggaagcattgctggaattcattacaccagtggatggtgatattgaacatatgctg acctttatgcgcgatctgcatcgttatacggcgcgcaatatgggcgatgagcggatgtgg ccgttaagtatgccatgctacatcgcagaaggtcaggacatcgaactggcacagtacggc acttctaacaccggacgctttaaaacgctgtatcgtgaagggctgaaaaatcgctacggc gcgctgatgcaaaccatttccggcgtgcactacaatttctctttgccaatggcattctgg caagcgaagtgcggtgatatctcgggcgctgatgccaaagagaaaatttctgcgggctat ttccgcgttatccgcaattactatcgtttcggttgggtcattccttatctgtttggtgca tctccggcgatttgttcttctttcctgcaaggaaaaccaacgtcgctgccgtttgagaaa accgagtgcggtatgtattacctgccgtatgcgacctctcttcgtttgagcgatctcggc tataccaataaatcgcaaagcaatcttggtattaccttcaacgatctttacgagtacgta gcgggccttaaacaggcaatcaaaacgccatcggaagagtacgcgaagattggtattgag aaagacggtaagaggctgcaaatcaacagcaacgtgttgcagattgaaaacgaactgtac gcgccgattcgtccaaaacgcgttacccgcagcggcgagtcgccttctgatgcgctgtta cgtggcggcattgaatatattgaagtgcgttcgctggacatcaacccgttctcgccgatt ggtgtagatgaacagcaggtgcgattcctcgacctgtttatggtctggtgtgcgctggct gatgcaccggaaatgagcagtagcgaacttgcctgtacacgcgttaactggaaccgggtg atcctcgaaggtcgcaaaccgggtctgacgctgggtatcggctgcgaaaccgcacagttc ccgttaccgcaggtgggtaaagatctgttccgcgatctgaaacgcgtcgcgcaaacgctg gatagtattaacggcggcgaagcgtatcagaaagtgtgtgatgaactggttgcctgcttc gataatcccgatctgactttctctgcccgtatcttaaggtctatgattgatactggtatt ggcggaacaggcaaagcatttgcagaagcctaccgtaatctgctgcgtgaagagccgctg gaaattctgcgcgaagaggattttgtagccgagcgcgaggcgtctgaacgccgtcagcag gaaatggaagccgctgataccgaaccgtttgcggtgtggctggaaaaacacgcctga

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