Escherichia coli K-12 MG1655: b3829
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Entry
b3829 CDS
T00007
Symbol
metE
Name
(RefSeq) cobalamin-independent homocysteine transmethylase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
eco
Escherichia coli K-12 MG1655
Pathway
eco00270
Cysteine and methionine metabolism
eco00450
Selenocompound metabolism
eco01100
Metabolic pathways
eco01110
Biosynthesis of secondary metabolites
eco01230
Biosynthesis of amino acids
Module
eco_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
eco00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
b3829 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
b3829 (metE)
Enzymes [BR:
eco01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
b3829 (metE)
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Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-GeneID:
948323
NCBI-ProteinID:
NP_418273
Pasteur:
metE
RegulonDB:
RDBECOLIGNC00576
ECOCYC:
EG10584
ASAP:
ABE-0012520
UniProt:
P25665
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Position
4013053..4015314
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AA seq
753 aa
AA seq
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MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLP
VGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFN
TNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPVTWLWLGKVKGEQFDR
LSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLL
TTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRAD
LTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLR
DALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRAR
FKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERLGLDVL
VHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPITVEWAKYA
QSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDE
PALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDAD
VITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERL
WVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atgacaatattgaatcacaccctcggtttccctcgcgttggcctgcgtcgcgagctgaaa
aaagcgcaagaaagttattgggcggggaactccacgcgtgaagaactgctggcggtaggg
cgtgaattgcgtgctcgtcactgggatcaacaaaagcaagcgggtatcgacctgctgccg
gtgggcgattttgcctggtacgatcatgtactgaccaccagtctgctgctgggtaacgtt
ccggcgcgtcatcagaacaaagatggttcggtagatatcgacaccctgttccgtattggt
cgtggacgtgcgccgactggcgaacctgcggcggcagcggaaatgaccaaatggtttaac
accaactatcactacatggtgccggagttcgttaaaggccaacagttcaaactgacctgg
acgcagctgctggacgaagtggacgaggcgctggcgctgggccacaaggtgaaacctgtg
ctgctggggccggttacctggctgtggctggggaaagtgaaaggtgaacaatttgaccgc
ctgagcctgctgaacgacattctgccggtttatcagcaagtgctggcagaactggcgaaa
cgcggcatcgagtgggtacagattgatgaacccgcgctggtactggaactaccacaggcg
tggctggacgcatacaaacccgcttacgacgcgctccagggacaggtgaaactgctgctg
accacctattttgaaggcgtaacgccaaatctcgacacgattactgcgctgcctgttcag
ggtctgcatgttgacctcgtacatggtaaagatgacgttgctgaactgcacaagcgcctg
ccttctgactggttgctgtctgcgggtctgatcaatggtcgtaacgtctggcgcgccgat
cttaccgagaaatatgcgcaaattaaggacattgtcggcaaacgtgatttgtgggtggca
tcttcctgctcgttgctgcacagccccatcgacctgagcgtggaaacgcgtcttgatgca
gaagtgaaaagctggtttgccttcgccctacaaaaatgccatgaactggcactgctgcgc
gatgcgctgaacagtggtgacacggcagctctggcagagtggagcgccccgattcaggca
cgtcgtcactctacccgcgtacataatccggcggtagaaaagcgtctggcggcgatcacc
gcccaggacagccagcgtgcgaatgtctatgaagtgcgtgctgaagcccagcgtgcgcgt
tttaaactgccagcgtggccgaccaccacgattggttccttcccgcaaaccacggaaatt
cgtaccctgcgtctggatttcaaaaagggcaatctcgacgccaacaactaccgcacgggc
attgcggaacatatcaagcaggccattgttgagcaggaacgtttgggactggatgtgctg
gtacatggcgaggccgagcgtaatgacatggtggaatactttggcgagcacctcgacgga
tttgtctttacgcaaaacggttgggtacagagctacggttcccgctgcgtgaagccaccg
attgtcattggtgacattagccgcccggcaccgattaccgtggagtgggcgaagtatgcg
caatcgctgaccgacaaaccggtgaaagggatgctgacggggccggtgaccatactctgc
tggtcgttcccgcgtgaagatgtcagccgtgaaaccatcgccaaacagattgcgctggcg
ctgcgtgatgaagtggccgatctggaagccgctggaattggcatcatccagattgacgaa
ccggcgctgcgcgaaggtttaccgctgcgtcgtagcgactgggatgcgtatctccagtgg
ggcgtagaggccttccgtatcaacgccgccgtggcgaaagatgacacacaaatccacact
cacatgtgttattgcgagttcaacgacatcatggattcgattgcggcgctggacgcagac
gtcatcaccatcgaaacctcgcgttccgacatggagttgctggagtcgtttgaagagttt
gattatccaaatgaaatcggtcctggcgtctatgacattcactcgccaaacgtaccgagc
gtggaatggattgaagccttgctgaagaaagcggcaaaacgcattccggcagagcgcctg
tgggtcaacccggactgtggcctgaaaacgcgcggctggccagaaacccgcgcggcactg
gcgaacatggtgcaggcggcgcagaacttgcgtcgggggtaa
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