Escherichia coli APEC O78 (APEC): APECO78_16515
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Entry
APECO78_16515 CDS
T02445
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ecoa
Escherichia coli APEC O78 (APEC)
Pathway
ecoa00230
Purine metabolism
ecoa01100
Metabolic pathways
ecoa01110
Biosynthesis of secondary metabolites
Module
ecoa_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecoa00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
APECO78_16515
Enzymes [BR:
ecoa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
APECO78_16515
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AGC88024
LinkDB
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Position
complement(3436175..3440059)
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AA seq
1294 aa
AA seq
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MEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKY
GPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLTN
EQWQQVTAELHDRMMETVFFDLDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGLA
LAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFRMI
KNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPTA
ISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVT
ALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIR
ADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRC
QEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLE
IWCNESQERYVLAIAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLP
LDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVT
GMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALT
NIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSM
KTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGAT
ALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAG
HCGINADIASLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSG
DRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKL
SFDINEDVAAPYIATVARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRTG
LEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMM
SNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRV
EVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHP
ERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
atggaaattctgcgtggttcgcctgcactgtcggcattccgaatcaacaaactgctggca
cgttttcaggctgccaggctcccggttcacaatatttacgccgagtatgtccattttgct
gacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaatat
ggtccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgtcct
ggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctacaa
caggtaaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgaccaat
gaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtctttttt
gatttagatgatgcagagcagttgtttgcccaccatcaaccgactccggtcacaagcgtt
gatttgctggggcagggccgtcaggcgctgatcgacgctaacctgcgtcttggcctggct
ctggcggaagatgaaattgactatctgcaggatgctttcacaaagcttggtcgtaacccg
aacgacatcgagctgtatatgttcgctcaggcgaactctgagcactgccgccacaaaatt
tttaacgccgactggattatcgacggtgaacaacagccgaaatcgctgttcaggatgatc
aaaaatactttcgaaaccacgccagatcacgttctctctgcttataaagataacgccgcc
gtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctacgat
ttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacggcg
atttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggtgcc
accgggcgcggcgcgaagccgaaagcgggtttggttggtttctccgtttccaacctgcga
attcctggcttcgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtcacc
gcgctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaatttggt
cgtccggcactgaatggctacttccgtacttatgaagaaaaagtgaacagccacaacggc
gaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaacattcgc
gccgatcacgtacaaaaaggcgagatcaacgtcggtgcgaagctggtcgttctcggcggc
ccggcaatgaacatcggtcttggcggcggagcggcgtcttccatggcgtcaggtcagtct
gatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgttgc
caggaagtgatcgaccgttgctggcagcttggtgatgctaacccaattctgtttatccac
gacgtcggtgcgggcggtctttctaacgcgatgccggagctggtgagcgacggcggacgc
ggcggtaaatttgaactgcgcgatattctaagcgacgaaccgggcatgagcccgctggaa
atctggtgtaacgaatcccaggaacgctacgtgctggcgattgctgccgatcaattaccg
ctgtttgacgaactgtgtaagcgtgaacgcgcaccctacgcggtgattggtgaagcgacc
gaagaactgcatctttctctgcacgatcgtcattttgataatcagccgatcgatctgccg
ctggacgtcctgcttggtaaaacgccgaagatgacccgcgatgtacaaacgctgaaagcg
aaaggcgacgcgctggcccgtgaagggatcaccattgcagatgcggtgaaacgtgtgctg
catctgccgactgtggcggaaaaaaccttcctggtgaccattggcgaccgcagcgtaacc
ggcatggtagcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgcgcg
gtcactaccgccagcctcgacagctactacggtgaagcgatggcgattggcgagcgtgcg
ccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgttaacc
aatattgctgcaacacagattggtgatatcaaacgcattaaactttccgccaactggatg
gcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagccgtgggc
gaagagctttgtccggcgctgggcctgacgatcccggtgggtaaagactctatgtcgatg
aaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctggtg
atttctgcatttgcccgcgtggaagatgtgcgtcacaccatcacgccacagctttctacc
gaagataacgcactgctgctgattgatttgggcaaaggcaataacgcgctgggcgcaacg
gcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgacgtcgcg
caactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctcgca
taccacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgctggt
cattgcggcattaacgcggatattgcctctctgggcgacgatcgcctggcggcgttgttt
aacgaagaactgggtgcggtgattcaggttcgtgccgctgaccgtgaagcggttgagtcc
gtactggcacagcatgggcttgctgattgtgtccattatgtagggcaggcggtttccggt
gaccgttttgtgattaccgccaacgggcagactgtattcagcgaaagccgcaccacgttg
cgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggagtgt
gctgaccaggagcaccaggcgaaatctaacgatgccgatcctggcctgaatgtaaaactg
tcgttcgatatcaacgaagatgtggcagcaccgtatattgccactgtcgcacgtccgaaa
gttgccgtactgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttccac
cgtgcaggctttgatgctatcgacgtgcatatgagtgacctgctgaccggacgcacgggc
ctggaagatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtgctgggt
gccggtgaaggttgggcgaagtcaatcctgttcaatgaccgtgtacgcgatgagtttgca
accttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatgatg
tctaacctgcgcgaactgatcccaggtagtgagttgtggccacgttttgtgcgcaatacc
tccgatcgctttgaagcgcgtttcagcctggttgaagtgacccaaagcccgtcgctgctg
ttgcaggggatggtgggctcgcaaatgccgattgctgtctctcatggtgaagggcgcgtg
gaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactgcgc
tatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttcaccg
aacggtattacggcagtcacgactgaaagtggtcgagtcaccattatgatgccgcacccg
gaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggatggc
ccatggatgcgtattttccgcaatgcgcgtaagcagttggggtaa
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