Escherichia coli O145 H28 RM13516 (EHEC): ECRM13516_0077
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Entry
ECRM13516_0077 CDS
T03011
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ecoh
Escherichia coli O145:H28 RM13516 (EHEC)
Pathway
ecoh00290
Valine, leucine and isoleucine biosynthesis
ecoh00660
C5-Branched dibasic acid metabolism
ecoh01100
Metabolic pathways
ecoh01110
Biosynthesis of secondary metabolites
ecoh01210
2-Oxocarboxylic acid metabolism
ecoh01230
Biosynthesis of amino acids
Module
ecoh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ecoh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ECRM13516_0077 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECRM13516_0077 (leuC)
Enzymes [BR:
ecoh01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ECRM13516_0077 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ECRM13516_0077 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Spo0M
Motif
Other DBs
NCBI-ProteinID:
AHG12773
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Position
complement(86544..87944)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaagacgttatacgaaaaattattcgacgctcacgtagtatacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccacc
atggatcacaacgtctctacccagaccaaagacattaatgcctgtggtgaaatggcgcgc
atccagatgcaggagctgatcaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggcgtgaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccactcacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgtgcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgttggcaattatcggtaaaactggcagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaatccgtgatttaagcatggaaggtcggatgaccctgtgc
aatatggcaatcgaaatgggcgcgaaagccggtctggttgcaccggacgaaaccaccttt
aactatgtcaaaggtcgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactctgcaa
gcagaagagatttcgccgcaggtcacctggggcaccaatccaggccaggtgatttccgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcagcagaa
aaagcgctggcctatatggggttgaaaccgggtattccactgacagaagtggctatcgac
aaagtgtttatcggctcctgcaccaactcgcgcattgaagatttacgcgcggcggctgaa
atcgccaaagggcgaaaagtcgcgccaggcgtacaggcactggtggttcccggctctggc
ccggtaaaagcccaggcggaagcggaaggtctggacaaaatctttattgaagccggtttt
gaatggcgcttgcctggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccg
ggcgaacgttgtgcctccaccagcaaccgtaactttgaaggccgtcaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgccgcggctgtgaccggccatttcgcc
gacattcgcaacattaaataa
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