Escherichia coli O18 K1 PMV-1 (ExPEC): ECOPMV1_02100
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Entry
ECOPMV1_02100 CDS
T02847
Symbol
tycC
Name
(GenBank) Tyrocidine synthase III
KO
K26578
colibactin biosynthesis nonribosomal peptide synthase
Organism
ecoi
Escherichia coli O18:K1 PMV-1 (ExPEC)
Pathway
ecoi01054
Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:
ecoi00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01054 Nonribosomal peptide structures
ECOPMV1_02100 (tycC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
ecoi01008
]
ECOPMV1_02100 (tycC)
Polyketide biosynthesis proteins [BR:
ecoi01008
]
Polyketide synthase (PKS)
PKS-NRPS hybrid
Bacterial type (modular)
Colibactin synthetase
ECOPMV1_02100 (tycC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
PP-binding
AMP-binding_C
Motif
Other DBs
NCBI-ProteinID:
CDH65521
LinkDB
All DBs
Position
complement(2137692..2144192)
Genome browser
AA seq
2166 aa
AA seq
DB search
MTIHHAALARMLPAEKKEKLLRQLAQSGVSPSRIPIIKADPAQAIPLSFNQERLWFLQKY
DSTATNYNLYVVYRLHGVVDMPMLTEALRHVQARHAILRTRIIVRNDRPCQVIDDASSLV
LDTVTLAAQAPTSALDAVIQQVINTRFDLARGPLWGVTQIIQPDQGCHLVFCAHHIIIDG
ISLRLLFDELQQQYARLHAGNETSLPPPPLQYADYAFWQREWFQDTLLANELAYWRARLQ
DAPLLSTFPSLHPRPAQPSTHGSRFSITLDETLSLALKHVARTQETTPFVLMLTAFQLVL
MRYAQQQRLVIGMPVSGRIRPELQSSIGYYASTAVIYTDFNGVEVGREALQRVKASVKET
QGRQQLPFENLVNMLDLPRSLSHSPLFQILYIYHNHVTPRAFTLAGAYWEQVTYHNQTVK
YDMTVEVFQNDATFDVSFEYDLGLYDADVVKQIAEALRQHCLSLTSSLETPIGAIPLHAP
ETATPRRDPLNATNVPWLGPQDVLRIIEQRCVQHPKQLAIQQHDGTLTYAELWARVQFIA
MRFRAHGIQPGDRIGVLLPRHRDVIATMLATWFVGACYVPFDIHQPAARLQRLMQRARLV
CLVVRQPGEWGEIVQLSLPELMQDMSNAIRYSTPCALLPDMQAYLLFTSGSTGEPKGVCV
VHRGLLNLLLDMQRTFAVGSQDRLLSVTTPTFDISFLEYLLPLISGASLYLTEAERAADS
FRMIPLIADYRPTLMQATPSFWHGLLMAGWRGDPELCVLAGGEALPTKVAEELLRCCGSL
WNLYGPTETTIWSLKSQITQAENITLGAPIANTRIYILDNEGHPVPQGVDGELYIAGDGV
AQGYDGQPELNAQFFLSEPGVPGGRMFRTGDLVRSDAQGQLFFVGRKDSQIKLRGYRIEL
GEIERTLARHPHVDAAVVACIERAPLHKALAAFIITSEPPSLFEQLKNELRQQLPDYMVP
TLWQRVADFPNTDNGKIDRKRLAENFVADSSLVSPQTQALSDTEQMLLALWMRYLPIKNV
DPECDFFRLGGHSLLAVTLVAEINRTFHCALTLKDIFHYSTLRALSARIAQQSITDAAAS
QDDWVIVHDPEHRHQPFPLTDVQRAYWLGRQTGATSIATHIYHEFDVEHFNVTRFTHAVN
ALIARHEMLRARVLPDGTQQILAQVPAYQLEQRDLSALSPNARNDALMAIRDRLSHHVHP
ADRWPLFDFSYSACTAQHGRLHFSLDLLIADALSMRTLQQELMMLYREPHVSLPLLPFSF
RDYVQALLVEQASEAYARDQAYWQRALPQLYGPPTLPVQGDLAQLSAIRFVRRRHRLSAH
NWGVLSALAQRTRITKTALLLTVFSQVLARWSLSPTFTLNLTLFNRPQGYPNAEAVIGDF
TAVSLLNVCYDSQHSYAHNAQRIQVQLWEDLEHRRFSGIRASEALIHSGRFHAPMPVVFT
SMLDIDGETTAQDPRDTTRFTLCPDANITQTPQVWLDHQVIELAGELHFNWDAVEQLFDT
TLLDQMFGAYCHALQALVAMPQSWWGVNSSLALPTVSAPVTQAPAPTALLHHGLLRQAAL
TPQETALISPIRELTYRQLSTAADHVARALLALGVQHGDRVAVVMEKGWQQIAAVHGILR
LGAVYLPVDPVLPPQRRQLLLTVGEVRVQVTQPGLTQLEPSLPVLIIDDGMLDTPAAPLP
EVAGDVTDLAYIIFTSGSTGTPKGVMIDHRAAMNTLEDINERFGLNAQDRVFGLSSLSFD
LSVYDAFAPFMVGAALVLPEAGREKDPRHWQTVMAHGHVSVWNAVPALMQMLCEYHSGDR
MSYPTLRLALLSGDWIPLTLPEQMRERLNETMDIISLGGATECAIWSVYYPIGEVESTWT
SIPYGRGLRNQPVYVLNAQLEECPVGVEGEICIGGMGLAQGYLNDAEKTAASFVWREASG
ERIYRTGDRGRYFADGQVAFLGRNDTQVKVNGYRIELGEVKSHLEQLDSVGSAAVVCHQG
QLYAFITAAENLHPDDTDALLARVRAQLAVQLPYYLLPQHFFLLKVLPMTGNGKIDQAAM
VQEVIQRMSQSTSQKSRALAHASPYEQQVAALWCEVLQREQIGLNDNFFEAGGGSIQIVL
LHRRIEEIFKVTVPIAELFRLTTVKRIAGYLQAMQDNARAVNQTQQRDASRSRAQQRLVR
RHQRQR
NT seq
6501 nt
NT seq
+upstream
nt +downstream
nt
atgacgatacatcatgccgcattggcgcgaatgttaccggcggaaaaaaaggaaaagcta
ttacgacagttggcgcaatcaggcgtgtcgcccagccgcattcccatcatcaaagcggat
ccggcgcaggcaatcccgctgtcgtttaatcaggagcggttgtggtttttgcaaaaatac
gacagtaccgccactaactacaacctttatgtggtgtatcgtttgcatggcgtggtggat
atgccgatgctcacggaggcattgcgccatgtgcaagcacgccacgccatcttgcgtacc
cgtatcatagtacgtaacgatcggccttgccaggtgatagatgatgcgtcttcgttagtt
ctcgatacggtcacgctggcagcgcaggccccaacttcagcgctagatgcggtaattcag
caggtgataaacacccggttcgatctggcacgcggtcctctgtggggggtaactcagatt
attcaacccgatcaaggttgtcatttggtgttttgcgcgcaccatatcatcatcgacggt
atctcgttacggctattgttcgatgagttacagcagcagtatgctcgattgcatgctggt
aatgaaacgtcgctgcctccgccgccgctgcaatatgccgattatgccttctggcagcgc
gaatggttccaggataccttgctggcgaacgaacttgcctactggcgtgcgcgtttgcaa
gacgcgcctctgctgtcgacatttccatcgctgcacccgcgcccggcacaaccctctaca
catggttcccggttcagcatcaccctggatgaaacattaagcctcgcgttgaaacacgta
gcccgcacgcaggaaacaacgccgttcgtgctgatgctgactgccttccaactggtgctg
atgcgttacgctcagcaacagcgattggtgataggcatgccagtatcggggcgcattcgc
ccggaattgcagagtagcattggttattatgccagcactgcggttatctacaccgatttt
aatggggttgaggtagggcgcgaggcgctccagcgtgtgaaggccagcgtgaaagagacg
caggggcgccagcaactgccgtttgaaaacttggtgaatatgctggatctccctcgcagc
ctttcccattcaccgttgttccagatcctctatatctaccataaccacgtgaccccacgc
gcttttaccttggctggtgcgtattgggagcaggtgacgtatcacaatcagaccgtcaaa
tacgacatgacagtcgaggtgttccaaaacgacgccacgttcgacgtctcctttgagtac
gatttggggttatacgatgctgatgtggtgaagcagattgccgaggcgctgcgtcagcac
tgcttatcgttgacatcatcactggagaccccgataggggcgatccctctgcatgcaccg
gagaccgcaacgccgcggcgtgatccgctcaacgccactaacgtcccgtggctcgggccg
caggatgtgctgcgtatcattgaacagcgctgtgtgcagcacccaaagcaactggcaata
cagcagcatgacggcacactgacctacgctgagctctgggcgcgtgtgcagttcatcgcg
atgcgttttcgagcgcatggcatacaaccgggcgatcgtattggcgtgctgttgccacgt
cacagggatgtgattgcaaccatgttggcgacgtggtttgtgggggcgtgctacgtgccg
ttcgatattcatcagcctgccgcgcgtttgcaacgccttatgcaacgcgcgcgtttggtc
tgtctggtggtccgtcagccgggagagtggggtgaaattgtacaactgtcgttgccggaa
ttgatgcaggacatgtcgaatgcgatccggtattctacaccttgcgcgctgttgccggat
atgcaggcctacctgttgtttacctccggcagtaccggtgaacctaaaggcgtgtgcgtt
gttcaccgcgggttgctgaacttgttgttggatatgcagcgtacctttgcggttggctcg
caagaccggctgctctcggtgacgacgccaacatttgatatctcattcttggagtatctg
ttgccgctgatctccggtgcgagtctctatctgacagaggcggaacgcgccgcagacagc
ttccgtatgattccgctgattgccgactatcgaccaacgctgatgcaggcgacgccctcg
ttctggcacgggctgttgatggcgggttggcgtggcgacccggaactatgtgtgctggca
ggcggtgaagcgctgccaacgaaagtggcggaagaactgttgcgctgttgtggttcattg
tggaacctctacggtcccaccgaaacaaccatttggtcgctgaaatcgcagataacccaa
gcggaaaacatcaccctcggcgctcccattgccaatacccgtatatacattctggacaat
gagggccatccagtgccgcaaggcgttgacggcgagctttacatcgccggggatggtgtg
gcgcaagggtatgatgggcagcctgagttgaacgcacagttcttcttgtcagaaccaggg
gtccccggtggcaggatgttccgcactggcgatctggtcaggagtgatgcgcaggggcag
ttgttttttgttgggcgcaaagatagccagatcaaactgcgcggttatcgtattgagtta
ggcgaaattgaacggacgttggcacggcatccgcatgtggacgccgcggtggtggcctgt
attgaaagagcaccgttacacaaagcactggcagcattcatcatcaccagtgagcctccc
tcgctattcgagcaactgaaaaacgagcttcggcagcaactgccagactatatggtgcca
acgctgtggcagagggtggccgacttcccgaacactgacaacggtaaaatcgatcgtaag
cggttagcggaaaatttcgttgccgatagctcccttgtgtcgccgcagacgcaagcgctg
agcgacacggaacagatgttgctggcgctgtggatgcgctatttgccgataaaaaacgtc
gatcctgagtgcgatttctttcgcttggggggacattcgctgttggcggtaacgttggta
gcagagatcaaccgcacttttcactgcgccttgaccctgaaggacattttccactactcc
acactacgggcactgagtgcgcgtattgcacagcaatctatcacggacgctgccgcgtct
caggatgactgggtgatagtgcacgaccctgagcatcgtcatcaaccgttcccattgacg
gatgttcagcgcgcctactggcttggacgacagacgggtgctacctcgatcgcgacccac
atctaccatgaatttgacgtagaacactttaatgttacgcgttttacccatgcggtgaat
gcgctgatcgctcgccatgaaatgctacgtgcgcgggtactccccgacggtactcagcag
attctggcgcaagtgccggcgtatcagttagagcagcgcgatctgagtgctttgtcccct
aacgcacgaaacgatgccttgatggcgatccgcgatcggctgtcgcatcatgtgcatccc
gcagatcgttggccgctgtttgatttcagttattcggcttgcacggcgcaacatggccgc
ttgcatttcagtctcgatctgctgattgccgatgctctgagtatgcgcacgctacagcag
gagttgatgatgctgtaccgtgagccccatgtgtcactgccgttgctaccgttctctttt
cgtgactacgtgcaggcgctgttggtagagcaggcgagtgaagcctatgcacgcgatcag
gcctattggcaacgggcgctgccgcagctgtatggcccaccaacgctgcccgtacagggc
gatttggcgcaactgtctgcgatcaggttcgtacgtcgccgtcatcggctgtcagcccac
aactggggagtgctgagcgcgctggcccaacgcacacgtatcaccaagacggcattgttg
ttgacagtctttagccaagtgctggcacgttggagccttagcccgacgtttacgctcaat
ctgacgttgttcaaccgcccgcagggttaccccaacgcagaggcagttattggtgatttt
accgctgtcagcttgctgaatgtttgttacgacagccagcactcttatgcccacaacgct
cagcgtattcaggtgcaactgtgggaagatctcgaacatcgtcgtttcagtgggatccgc
gccagcgaggcgctgatccatagcggtcgtttccatgcgccgatgccggtggtattcact
agtatgttggatatcgacggggagacgactgcgcaagaccctcgggacacaacccgtttt
actctgtgtccggacgccaatattacccaaacaccgcaggtgtggctcgatcaccaggtg
atcgagttggctggggagttgcatttcaactgggacgcggtcgagcaactgtttgatacc
acgctgctggatcagatgtttggtgcttattgtcatgcgctgcaggcgctggttgccatg
ccgcaaagttggtggggggtaaatagttctctggcgctgcccaccgttagtgcaccggtc
acgcaggctcctgcacctacggccttgttgcaccatggattactgcgtcaggcagcactg
acgccacaggaaactgcgctgatcagtcctatccgtgaattgacctatcgccaactgtcg
acggcggcggatcatgtggcccgcgccctgttagcgctgggcgtgcagcatggcgaccgc
gtggcggtggtgatggaaaaaggctggcagcagattgccgccgtacacggcattttacga
ctgggtgcggtctatctgccagtggatccggtgctaccgccacagcgtcgccagcttttg
ctgacggtgggcgaggtgcgggtacaagtaacgcagccgggtctcacgcaattggagccg
tcgctgcccgtgctgatcatcgacgacggaatgctggacacgcctgctgcgccgttgcct
gaagtggctggggatgtcacggatctggcctatatcattttcacttccggctccaccggt
accccgaaaggagtgatgatcgaccaccgtgcggccatgaacacgctggaagacatcaac
gaacgctttggcctcaatgcgcaggatagggtgttcgggctgtcatcattgagctttgac
ctgtcggtttacgatgcctttgcgccttttatggtgggtgcagcgctggtactgccggaa
gcaggacgggaaaaagatccgcgtcattggcagacagttatggcacacggtcatgtaagc
gtctggaatgcagtgcccgcactgatgcagatgctgtgcgaataccacagcggcgatcgg
atgagttatccgacgttgcgtctggcactgttgagcggcgactggatcccgctaacgtta
ccggagcagatgcgcgagcggctcaatgaaacgatggacatcatcagtctgggtggagcg
accgagtgcgccatctggtcggtctactacccgataggtgaggtggaatcgacgtggacc
agtattccctacggtcggggcctgcgcaaccagccagtatacgtgctaaatgcgcaactg
gaggaatgtccggtcggggtggaaggagagatttgcattggcgggatggggctggcacaa
ggctacctgaacgacgcagagaaaacggcggcgagctttgtctggcgcgaagcgagtggt
gagcgaatttaccgcactggggatcgcgggcgctactttgctgacgggcaagtcgccttt
ttggggcgcaacgatacccaagtgaaggtgaatggttaccgtatcgaactgggggaagtc
aaaagccaccttgaacagctcgacagcgtagggagtgccgccgtggtgtgccaccaggga
cagctgtatgcctttatcactgccgcagaaaacctgcatcctgacgatactgacgccctg
ttagcgcgtgttcgtgctcagttagccgtgcagttgccgtattacctgctgccccaacat
ttctttcttctcaaggtgctgccgatgacaggcaacggcaaaattgatcaggcggcaatg
gttcaagaggttatccaacgtatgtcgcaatctacatcacagaagtcgagggccctcgcg
cacgcctcgccctatgaacagcaggtggccgctctctggtgcgaggtactacaacgagaa
cagatcggactgaatgacaacttttttgaagcggggggcggctcaatccagatcgtgctg
ttgcatcgccgtattgaggagatttttaaggttacggtacctattgctgagctatttcgc
ttaaccaccgtgaaaagaattgccggttatttgcaggctatgcaggacaatgcacgggcg
gtgaatcaaacacagcagcgtgatgcttcccgatcccgcgcccagcaacgacttgtacgt
cgtcaccagcgtcagcgttaa
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