KEGG   Escherichia coli O18 K1 PMV-1 (ExPEC): ECOPMV1_02102
Entry
ECOPMV1_02102     CDS       T02847                                 
Symbol
grsB
Name
(GenBank) Gramicidin S synthase II
  KO
K26565  colibactin biosynthesis nonribosomal peptide synthase
Organism
ecoi  Escherichia coli O18:K1 PMV-1 (ExPEC)
Pathway
ecoi01054  Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:ecoi00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01054 Nonribosomal peptide structures
    ECOPMV1_02102 (grsB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:ecoi01008]
    ECOPMV1_02102 (grsB)
Polyketide biosynthesis proteins [BR:ecoi01008]
 Polyketide synthase (PKS)
  PKS-NRPS hybrid
   Bacterial type (modular)
    Colibactin synthetase
     ECOPMV1_02102 (grsB)
SSDB
Motif
Pfam: AMP-binding Condensation AMP-binding_C PP-binding DUF7080
Other DBs
NCBI-ProteinID: CDH65523
LinkDB
Position
complement(2147318..2152114)
AA seq 1598 aa
MEQQGIMRQLPTDDQTIVDYLYRIAGEYGEKAAVLMGDAALSYHDLNARSNQLAHYLRGL
GIGEDRVVAIRLPRGMAMLIAIFAIVKAGGAYLPLAYNAPRSRIENILSNSGAVCLIGTD
DGDRWPIPRVEIDSAAVSAMPTTDLRYRPHARQLAYIIYTSGSTGVPKGVATEHAALLNR
IVWMQNAYPISSQDVLFQKTVYTFDVSVWEMFWWAMYGASVVLLPSGLESDPRTLARLIQ
RHRVSVVHFVPSMLNLFVEYLEMKQDPRLTASLRLVFSSGEKLTVHSVARFYQSVAQGDL
INLYGPTEAAIDVSHHRCLRGYDYDDIPIGQAIDGCRLYVLDDHGNPVADGEEGELYLAG
IGLARGYLNNVALTDRCFTIHPTLRHLGKPERLYKTGDLVWRDGESQQIHYIGRNDFQIK
IRGLRVELGEIEAHAMRFPGVQQAVVVADQDDPDNQLIYAFVVSSVPLNLAALMDALSKN
LPAYMLPNRLLAMSELPLSDNGKCCRKTLLDLARAYSASRVDLRETPAVRYLPLSSAQSS
MWFMQQLAPHTALYNNPTALLLEGELDRTRMDGAIRQLMSRHTLLRAMAETHNGQPVLAV
PQCVSSQALLTIVPLPSVSDDNALQAMINQRAAHPMPLTSGTPLCRFELLTLDDDRSVLL
IHLHHIISDGWSKGVLLRELQAAYNGESLTPEPLLEYADYMEYQEEWRQSDAYQDAMRYW
QNTLAGTLPILDIPTDQPRQKVARYQGAFVAFALSANTCERVLAAARAQRVSLYNYLLTA
FVLLLHRNARQQEYIVGMPIAARLTKEQEHMIAPLVNVLPLRLPLDEAASFSELVQTIRG
ILFAAFRHQRLEFTDIVRAVNVDRSAGHFPIYQCMFQLDNMPLASPTLNGVNVTPLLLDT
SASQVDISLSMQHIDGRITGTFEYDAGLYSADRIQHLVAQWRELLDEASSQPTQLVRDLI
RFTPREHAWLARHNATEVALPPVDNLLALVLPHCQQRPTQVALRHADDAMTYGELQQATM
QMCTWLRAQGVKRGESVALQLPFCFELIIAQLAILSLGASYVPLDGNAPAARNALILAQA
TPCMLLVAQPLESPHGLTIPWVLVPDWRSLLTEIPNLPVSVAPDALDCDAVVIFTSGTTG
QPKGVRLSQRNLVNLTASFISSYQVTHQDVLLPITSVASASFVGEVLPLLAAGGTLVLAQ
KAQSLDSDALIALLASQRVTILSTTPSLSASLSVLAQSMGSLRLFLCGGEALEYEQIAPL
LPHMAVVNGYGLTESGICSTYFPVAKRREQETGALPIGRPIQNTQAYVVDAYNRLVPPGA
CGELCFSGLGISPGYLDARQDPERFVELPEYPGVRVLKTGDRARWATDGMLFYLGRQDRQ
VQIRGYRVELGDIESLLKQHPDIADAWVDVRRNAAATPLLVAFYCSVNGVALDAQQLRVW
LSLRLPLHMLPLLYVPLSAMPLGVNGKIDPQCLPLVDLRQLEGPGEYVPPATELEQRLAE
IWQQLLGLERVGTTTNFFDLGGHSLLLVQMQQYIGQQCGQHVALVDLLRFTTIKRLAEFL
LAPDAAQGTTGDQTQLRAAKQRLAFGHTRWAATTDSHH
NT seq 4797 nt   +upstreamnt  +downstreamnt
atggaacagcaagggattatgagacagttgcctaccgacgaccaaacgatagtcgactat
ttgtatcgtatcgccggagaatatggggaaaaagccgctgtattgatgggggacgcggcg
ctgagctatcacgatcttaatgcacgctctaaccaactggcgcattatctgcgtgggctg
gggatcggcgaggatcgtgtggtagctatccgcctgccgcgcggcatggcaatgctgatt
gccattttcgctattgtaaaagctggtggtgcctatttaccgctggcgtacaatgcaccg
cgcagccgcattgaaaatatactgagcaacagcggcgctgtttgtctgatcggtactgac
gatggtgatcgctggccgattcctcgcgtcgaaatcgacagcgcggcggtcagtgccatg
ccaacgacggatctgcgttaccgaccacatgcgcggcaactggcgtatattatttacacc
tccggttccaccggtgtccctaaaggggtggcgacggaacatgcagcgctgctaaaccga
attgtctggatgcagaacgcttatcctatcagttctcaggacgtgctgtttcagaagacg
gtgtacacctttgacgtctctgtctgggagatgttctggtgggcgatgtacggcgcatct
gtagtgctgttaccgtccggactggagagcgatccgcgaaccttggctcgactgattcag
cgtcaccgcgtgtcggttgtgcactttgtcccttcgatgctgaacctgtttgtcgagtat
ctggagatgaaacaggatcctcgtttgaccgcctcattgcgattagtgttttccagcggt
gagaaactcacggtccacagtgtggctcgcttttatcaatcggtggcgcagggtgatctt
ataaatctctatggcccgaccgaagcagcaatcgatgtcagtcatcaccgctgcctgcgc
gggtacgactacgacgatatccctatcggtcaagcgattgacggttgccgactctatgtg
ctggatgaccatggtaatccggtagcagacggcgaagagggcgaactgtatctcgctggt
atcgggctggcacgtggctatctcaacaacgtggcgttaactgatcgctgttttactata
catccaactttgcgccatttagggaaaccggagcggctgtataaaactggagatctggtg
tggcgcgacggggaaagccaacaaattcattacattggccgtaatgattttcagattaaa
attagagggttgcgcgttgaattgggagaaatcgaagcccatgcgatgcgtttcccgggg
gtacagcaggcagtcgtggtggcggatcaggatgatcccgacaatcagttgatttacgct
tttgtcgtcagtagcgtgccgctcaatttggcggccttaatggacgcactgtccaaaaac
ttgcctgcctacatgctgccgaaccgtttgttggcaatgtcagagttaccactctccgac
aatggcaagtgctgtcgtaaaacgttgctcgacttggcgcgggcgtactcagccagtcgc
gtcgatttacgtgaaactcccgccgtgcgctacctaccgttgtcatcggctcaatcgtcg
atgtggtttatgcaacaattggcgccgcatactgcactatacaataaccccaccgccttg
ctgcttgaaggagaactggatcgcacgcggatggacggcgcgattcgtcaattgatgagt
cggcatactctgttacgtgctatggcggaaacccacaatggacaaccagtattggcggtg
cctcagtgcgtatcgtcgcaggcgttgctgaccatagtgccactcccctcggtgagtgat
gataacgcgctacaggcgatgatcaaccagcgtgcggcacaccccatgcccttaacgtca
ggcacaccgctgtgccggtttgaactgttgacgctcgatgacgatcgtagcgtattgttg
attcatctgcaccacatcatcagtgatggctggtcgaaaggcgttttgttacgcgaattg
caggccgcatataacggtgaatcgctgacgccagaaccgttgttggagtatgccgactac
atggagtaccaagaagagtggcgtcagagtgacgcctatcaggacgcgatgcgttactgg
caaaataccctggcggggacgttgccgattcttgatatccccaccgatcaaccgcgtcag
aaggtggcacgttaccaaggcgcgtttgttgccttcgcattgtctgccaacacatgcgag
cgagtgttggcggcggcgcgtgcgcagcgcgtgtcgttgtataactatctgctgaccgcc
ttcgtcctcctgctgcatcgtaatgcgcgtcaacaggaatacatcgtcggtatgccgatt
gctgcgcggctgacgaaagaacaggagcatatgatcgcgccgctggtcaacgtactaccg
ctgcgcttacctcttgacgaagcggcatcgttttccgagttagtacagacgatcagaggt
attctgtttgccgctttcaggcaccagcgtctcgaatttaccgacatagtgcgcgcagtg
aatgtggatcgcagcgccggacatttcccaatatatcagtgcatgttccaactcgacaat
atgcctctggcgagcccgacactaaacggtgtcaacgttacaccattattgttggatacc
agtgcatctcaggtggatatttcgctaagtatgcagcatatcgatgggcgcatcaccggc
actttcgaatacgacgctgggttatacagtgcggatcgtattcagcacctggtggcgcag
tggagagaactgctagatgaggccagcagccaacccacgcagttagtccgcgatttgatt
cgtttcacccctcgagagcacgcttggctggcgcggcacaacgccactgaagttgctctg
ccgcccgtagataacctgctggcgctagtgttaccgcactgccagcagcgccctacacag
gtggctttgcgccacgctgacgacgccatgacctatggcgaattgcaacaggccacgatg
cagatgtgtacttggctgcgtgcgcaaggcgtaaaacgcggagaatctgtcgcactgcaa
ctgcctttttgtttcgaattgattatcgcacaattggcgatcctctctttgggggcgagc
tatgtgccgctggatggtaacgcgccagcggcccgcaatgccctgatcttggcgcaggca
acgccgtgcatgctgctggtggcgcaaccgctggaatcccctcatgggctgacgatacct
tgggtgctagtgcctgactggcgtagcctgctgacagaaataccgaacctgccagttagt
gttgcgccagatgctttagattgcgatgcggtggtgatctttacctccggtactaccggg
cagcccaaaggcgtccgactcagccaacgtaatctggtcaacttaaccgcatcctttata
tccagctatcaagtgacgcatcaggatgttctgctacccattacctcagtcgcgtctgct
agctttgtcggggaggtactgccgctgctcgccgctggcggtaccttagtattggcgcaa
aaagcgcagagtttggatagtgatgcgctcattgcgctgctggcatctcagcgggtgact
atcctgagcaccaccccatcgctttctgccagcctctctgtgctggctcagtcgatggga
tcgctgcgcttgtttctgtgcggtggtgaagcgttagagtatgagcagatagcgccgctt
ctgccgcacatggcagtggttaacggttatggcctgaccgaaagcggtatctgctcgacc
tactttcctgtcgcaaagcgtagggagcaagaaacgggagcattgcccattggccgcccg
attcagaacacccaagcttatgtggtggatgcatataatcgtttggtaccgccaggtgcc
tgtggagaactctgtttctctggtctgggcatttcgcccggctaccttgatgcacgacag
gatcccgagcgctttgtcgagttgccggaataccctggcgttcgggtgctgaaaactggc
gatcgtgctcgttgggcaaccgacgggatgttgttctatctcggcagacaagatcgccaa
gtgcagatccgtggataccgagttgaactgggcgacatcgaaagcctactgaaacagcat
ccggatattgctgatgcgtgggtcgatgtgcgacgcaatgcggcggcaacgccgctacta
gtggccttctattgcagcgtcaacggcgttgcgctggatgctcagcaattgcgcgtatgg
ctcagcctgcggcttccgttgcatatgctgccgttgctctacgtgccgctgagcgccatg
ccgctaggtgtaaacggcaaaatcgatccccagtgcctgccgctggtcgatctgcggcag
ttggaagggccgggcgagtatgtccctccggcaaccgaactggaacagcgtctggcggag
atctggcagcagttgcttggcctggagcgtgtcggcaccaccacaaatttcttcgatctc
ggtggacactcacttctgctagtacagatgcagcaatacatcgggcagcagtgcggtcag
cacgtggcgttggttgacctgctgcgcttcactaccatcaaacgcttggcggaatttctg
ctggccccggacgcagcgcaagggaccacaggagatcagacacaactgcgtgcggcgaag
cagcgtttggcctttggtcacacgcgctgggcagccacaaccgacagtcatcactga

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