Escherichia coli O18 K1 PMV-1 (ExPEC): ECOPMV1_02102
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Entry
ECOPMV1_02102 CDS
T02847
Symbol
grsB
Name
(GenBank) Gramicidin S synthase II
KO
K26565
colibactin biosynthesis nonribosomal peptide synthase
Organism
ecoi
Escherichia coli O18:K1 PMV-1 (ExPEC)
Pathway
ecoi01054
Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:
ecoi00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01054 Nonribosomal peptide structures
ECOPMV1_02102 (grsB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
ecoi01008
]
ECOPMV1_02102 (grsB)
Polyketide biosynthesis proteins [BR:
ecoi01008
]
Polyketide synthase (PKS)
PKS-NRPS hybrid
Bacterial type (modular)
Colibactin synthetase
ECOPMV1_02102 (grsB)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
AMP-binding_C
PP-binding
DUF7080
Motif
Other DBs
NCBI-ProteinID:
CDH65523
LinkDB
All DBs
Position
complement(2147318..2152114)
Genome browser
AA seq
1598 aa
AA seq
DB search
MEQQGIMRQLPTDDQTIVDYLYRIAGEYGEKAAVLMGDAALSYHDLNARSNQLAHYLRGL
GIGEDRVVAIRLPRGMAMLIAIFAIVKAGGAYLPLAYNAPRSRIENILSNSGAVCLIGTD
DGDRWPIPRVEIDSAAVSAMPTTDLRYRPHARQLAYIIYTSGSTGVPKGVATEHAALLNR
IVWMQNAYPISSQDVLFQKTVYTFDVSVWEMFWWAMYGASVVLLPSGLESDPRTLARLIQ
RHRVSVVHFVPSMLNLFVEYLEMKQDPRLTASLRLVFSSGEKLTVHSVARFYQSVAQGDL
INLYGPTEAAIDVSHHRCLRGYDYDDIPIGQAIDGCRLYVLDDHGNPVADGEEGELYLAG
IGLARGYLNNVALTDRCFTIHPTLRHLGKPERLYKTGDLVWRDGESQQIHYIGRNDFQIK
IRGLRVELGEIEAHAMRFPGVQQAVVVADQDDPDNQLIYAFVVSSVPLNLAALMDALSKN
LPAYMLPNRLLAMSELPLSDNGKCCRKTLLDLARAYSASRVDLRETPAVRYLPLSSAQSS
MWFMQQLAPHTALYNNPTALLLEGELDRTRMDGAIRQLMSRHTLLRAMAETHNGQPVLAV
PQCVSSQALLTIVPLPSVSDDNALQAMINQRAAHPMPLTSGTPLCRFELLTLDDDRSVLL
IHLHHIISDGWSKGVLLRELQAAYNGESLTPEPLLEYADYMEYQEEWRQSDAYQDAMRYW
QNTLAGTLPILDIPTDQPRQKVARYQGAFVAFALSANTCERVLAAARAQRVSLYNYLLTA
FVLLLHRNARQQEYIVGMPIAARLTKEQEHMIAPLVNVLPLRLPLDEAASFSELVQTIRG
ILFAAFRHQRLEFTDIVRAVNVDRSAGHFPIYQCMFQLDNMPLASPTLNGVNVTPLLLDT
SASQVDISLSMQHIDGRITGTFEYDAGLYSADRIQHLVAQWRELLDEASSQPTQLVRDLI
RFTPREHAWLARHNATEVALPPVDNLLALVLPHCQQRPTQVALRHADDAMTYGELQQATM
QMCTWLRAQGVKRGESVALQLPFCFELIIAQLAILSLGASYVPLDGNAPAARNALILAQA
TPCMLLVAQPLESPHGLTIPWVLVPDWRSLLTEIPNLPVSVAPDALDCDAVVIFTSGTTG
QPKGVRLSQRNLVNLTASFISSYQVTHQDVLLPITSVASASFVGEVLPLLAAGGTLVLAQ
KAQSLDSDALIALLASQRVTILSTTPSLSASLSVLAQSMGSLRLFLCGGEALEYEQIAPL
LPHMAVVNGYGLTESGICSTYFPVAKRREQETGALPIGRPIQNTQAYVVDAYNRLVPPGA
CGELCFSGLGISPGYLDARQDPERFVELPEYPGVRVLKTGDRARWATDGMLFYLGRQDRQ
VQIRGYRVELGDIESLLKQHPDIADAWVDVRRNAAATPLLVAFYCSVNGVALDAQQLRVW
LSLRLPLHMLPLLYVPLSAMPLGVNGKIDPQCLPLVDLRQLEGPGEYVPPATELEQRLAE
IWQQLLGLERVGTTTNFFDLGGHSLLLVQMQQYIGQQCGQHVALVDLLRFTTIKRLAEFL
LAPDAAQGTTGDQTQLRAAKQRLAFGHTRWAATTDSHH
NT seq
4797 nt
NT seq
+upstream
nt +downstream
nt
atggaacagcaagggattatgagacagttgcctaccgacgaccaaacgatagtcgactat
ttgtatcgtatcgccggagaatatggggaaaaagccgctgtattgatgggggacgcggcg
ctgagctatcacgatcttaatgcacgctctaaccaactggcgcattatctgcgtgggctg
gggatcggcgaggatcgtgtggtagctatccgcctgccgcgcggcatggcaatgctgatt
gccattttcgctattgtaaaagctggtggtgcctatttaccgctggcgtacaatgcaccg
cgcagccgcattgaaaatatactgagcaacagcggcgctgtttgtctgatcggtactgac
gatggtgatcgctggccgattcctcgcgtcgaaatcgacagcgcggcggtcagtgccatg
ccaacgacggatctgcgttaccgaccacatgcgcggcaactggcgtatattatttacacc
tccggttccaccggtgtccctaaaggggtggcgacggaacatgcagcgctgctaaaccga
attgtctggatgcagaacgcttatcctatcagttctcaggacgtgctgtttcagaagacg
gtgtacacctttgacgtctctgtctgggagatgttctggtgggcgatgtacggcgcatct
gtagtgctgttaccgtccggactggagagcgatccgcgaaccttggctcgactgattcag
cgtcaccgcgtgtcggttgtgcactttgtcccttcgatgctgaacctgtttgtcgagtat
ctggagatgaaacaggatcctcgtttgaccgcctcattgcgattagtgttttccagcggt
gagaaactcacggtccacagtgtggctcgcttttatcaatcggtggcgcagggtgatctt
ataaatctctatggcccgaccgaagcagcaatcgatgtcagtcatcaccgctgcctgcgc
gggtacgactacgacgatatccctatcggtcaagcgattgacggttgccgactctatgtg
ctggatgaccatggtaatccggtagcagacggcgaagagggcgaactgtatctcgctggt
atcgggctggcacgtggctatctcaacaacgtggcgttaactgatcgctgttttactata
catccaactttgcgccatttagggaaaccggagcggctgtataaaactggagatctggtg
tggcgcgacggggaaagccaacaaattcattacattggccgtaatgattttcagattaaa
attagagggttgcgcgttgaattgggagaaatcgaagcccatgcgatgcgtttcccgggg
gtacagcaggcagtcgtggtggcggatcaggatgatcccgacaatcagttgatttacgct
tttgtcgtcagtagcgtgccgctcaatttggcggccttaatggacgcactgtccaaaaac
ttgcctgcctacatgctgccgaaccgtttgttggcaatgtcagagttaccactctccgac
aatggcaagtgctgtcgtaaaacgttgctcgacttggcgcgggcgtactcagccagtcgc
gtcgatttacgtgaaactcccgccgtgcgctacctaccgttgtcatcggctcaatcgtcg
atgtggtttatgcaacaattggcgccgcatactgcactatacaataaccccaccgccttg
ctgcttgaaggagaactggatcgcacgcggatggacggcgcgattcgtcaattgatgagt
cggcatactctgttacgtgctatggcggaaacccacaatggacaaccagtattggcggtg
cctcagtgcgtatcgtcgcaggcgttgctgaccatagtgccactcccctcggtgagtgat
gataacgcgctacaggcgatgatcaaccagcgtgcggcacaccccatgcccttaacgtca
ggcacaccgctgtgccggtttgaactgttgacgctcgatgacgatcgtagcgtattgttg
attcatctgcaccacatcatcagtgatggctggtcgaaaggcgttttgttacgcgaattg
caggccgcatataacggtgaatcgctgacgccagaaccgttgttggagtatgccgactac
atggagtaccaagaagagtggcgtcagagtgacgcctatcaggacgcgatgcgttactgg
caaaataccctggcggggacgttgccgattcttgatatccccaccgatcaaccgcgtcag
aaggtggcacgttaccaaggcgcgtttgttgccttcgcattgtctgccaacacatgcgag
cgagtgttggcggcggcgcgtgcgcagcgcgtgtcgttgtataactatctgctgaccgcc
ttcgtcctcctgctgcatcgtaatgcgcgtcaacaggaatacatcgtcggtatgccgatt
gctgcgcggctgacgaaagaacaggagcatatgatcgcgccgctggtcaacgtactaccg
ctgcgcttacctcttgacgaagcggcatcgttttccgagttagtacagacgatcagaggt
attctgtttgccgctttcaggcaccagcgtctcgaatttaccgacatagtgcgcgcagtg
aatgtggatcgcagcgccggacatttcccaatatatcagtgcatgttccaactcgacaat
atgcctctggcgagcccgacactaaacggtgtcaacgttacaccattattgttggatacc
agtgcatctcaggtggatatttcgctaagtatgcagcatatcgatgggcgcatcaccggc
actttcgaatacgacgctgggttatacagtgcggatcgtattcagcacctggtggcgcag
tggagagaactgctagatgaggccagcagccaacccacgcagttagtccgcgatttgatt
cgtttcacccctcgagagcacgcttggctggcgcggcacaacgccactgaagttgctctg
ccgcccgtagataacctgctggcgctagtgttaccgcactgccagcagcgccctacacag
gtggctttgcgccacgctgacgacgccatgacctatggcgaattgcaacaggccacgatg
cagatgtgtacttggctgcgtgcgcaaggcgtaaaacgcggagaatctgtcgcactgcaa
ctgcctttttgtttcgaattgattatcgcacaattggcgatcctctctttgggggcgagc
tatgtgccgctggatggtaacgcgccagcggcccgcaatgccctgatcttggcgcaggca
acgccgtgcatgctgctggtggcgcaaccgctggaatcccctcatgggctgacgatacct
tgggtgctagtgcctgactggcgtagcctgctgacagaaataccgaacctgccagttagt
gttgcgccagatgctttagattgcgatgcggtggtgatctttacctccggtactaccggg
cagcccaaaggcgtccgactcagccaacgtaatctggtcaacttaaccgcatcctttata
tccagctatcaagtgacgcatcaggatgttctgctacccattacctcagtcgcgtctgct
agctttgtcggggaggtactgccgctgctcgccgctggcggtaccttagtattggcgcaa
aaagcgcagagtttggatagtgatgcgctcattgcgctgctggcatctcagcgggtgact
atcctgagcaccaccccatcgctttctgccagcctctctgtgctggctcagtcgatggga
tcgctgcgcttgtttctgtgcggtggtgaagcgttagagtatgagcagatagcgccgctt
ctgccgcacatggcagtggttaacggttatggcctgaccgaaagcggtatctgctcgacc
tactttcctgtcgcaaagcgtagggagcaagaaacgggagcattgcccattggccgcccg
attcagaacacccaagcttatgtggtggatgcatataatcgtttggtaccgccaggtgcc
tgtggagaactctgtttctctggtctgggcatttcgcccggctaccttgatgcacgacag
gatcccgagcgctttgtcgagttgccggaataccctggcgttcgggtgctgaaaactggc
gatcgtgctcgttgggcaaccgacgggatgttgttctatctcggcagacaagatcgccaa
gtgcagatccgtggataccgagttgaactgggcgacatcgaaagcctactgaaacagcat
ccggatattgctgatgcgtgggtcgatgtgcgacgcaatgcggcggcaacgccgctacta
gtggccttctattgcagcgtcaacggcgttgcgctggatgctcagcaattgcgcgtatgg
ctcagcctgcggcttccgttgcatatgctgccgttgctctacgtgccgctgagcgccatg
ccgctaggtgtaaacggcaaaatcgatccccagtgcctgccgctggtcgatctgcggcag
ttggaagggccgggcgagtatgtccctccggcaaccgaactggaacagcgtctggcggag
atctggcagcagttgcttggcctggagcgtgtcggcaccaccacaaatttcttcgatctc
ggtggacactcacttctgctagtacagatgcagcaatacatcgggcagcagtgcggtcag
cacgtggcgttggttgacctgctgcgcttcactaccatcaaacgcttggcggaatttctg
ctggccccggacgcagcgcaagggaccacaggagatcagacacaactgcgtgcggcgaag
cagcgtttggcctttggtcacacgcgctgggcagccacaaccgacagtcatcactga
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