Escherichia coli O18 K1 PMV-1 (ExPEC): ECOPMV1_02108 Help Entry ECOPMV1_02108     CDS       T02847                                  Symbol pksJ Name (GenBank) Polyketide synthase PksJ   KO K26573   colibactin biosynthesis hybrid nonribosomal peptide/polyketide synthase Organism ecoi  Escherichia coli O18:K1 PMV-1 (ExPEC) Pathway ecoi01054   Nonribosomal peptide structures Brite KEGG Orthology (KO) [BR:ecoi00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01054 Nonribosomal peptide structures     ECOPMV1_02108 (pksJ)  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:ecoi01008]     ECOPMV1_02108 (pksJ) Polyketide biosynthesis proteins [BR:ecoi01008]  Polyketide synthase (PKS)   PKS-NRPS hybrid    Bacterial type (modular)     Colibactin synthetase      ECOPMV1_02108 (pksJ) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AMP-binding Condensation ketoacyl-synt Acyl_transf_1 Ketoacyl-synt_C PP-binding KR ADH_zinc_N_2 ADH_zinc_N PKS_DH_N CurL-like_PKS_C adh_short adh_short_C2 KAsynt_C_assoc RhiE-like_linker ADH_N PS-DH AMP-binding_C NAD_binding_10 Epimerase Thiolase_N Motif Other DBs NCBI-ProteinID:  CDH65529 LinkDB All DBs Position complement(2158359..2167979) Genome browser AA seq 3206 aa AA seqDB search MDNTSGDFPCNKMDTRKQLPLTPSQQGFLFHSLKDKKRSNYHEHFTCIFSQHVDSAHFKW ALETLFRKHECFRTDYNWEIDERPCQVVKTDVLPDIYVLDCEQEEIRFLLANDDIIIPVP QDDGIDAIIPQLLQADLKYPFSLKTIPVRAYLIQSTKESAFILSYHHIVMDGWSLSLFIK QLLQLYGAAVVSGVRDDSAIIPSSLKPLVDTLSARRHTFQHDYWAAYLREGTPTCIVPLS QYHTDTEAENNSYVNQTNHVEINLSPDVCQKIQTLCSDYRITPAVIFYVAWGILLQRWCY ADDVLFGATISGRNIPIDGIEETLGLFINTLPLRLRDDGATLLQHLQRMHQTLIAHYSNE HDALASIQRLVHKEGHAGDLFNTLVVLENYPVDMTLLSCASPVAIRHLSVHEQTHYPLTL TITQQKGFRFSIAYALNYLTNNMAQALLMHLSYLLEQLVDNPQRPIAALVNLSPCQQAQV LQPYLERMACRDWDSQSNVIEQFHQVAATSPAQVAVVDELCALTYSELAAQAEQLAAYLV QQGVMVGDTVGIISERRVNTVVAIIAIMLIGAAYVPISPDYPVGRMQEIIDDSGLALLLV HGKPLDALNVAQSDLCAFPVAPSVVFPVITPDSRAYVIYSSGSTGKPKGIAVAHRGLLRL IQGDSPLKVESGETTLLTCPFEFDVSVFEMWSTLLNHGKLVLLSKQALLDINHIRRTIAD EQVARAWFTSSLFNSYVAEGADFFGMLQHITVGGEAVSAWHVNDVMQKYPHLVVTNGYGP TENTIFTTAYRFNGLQPARVPIGYAVPGTSLYITDLHGHLLPIGATGELVAGGVGVAIGY QNNPALSATVFVPDPFIPGGMMYKTGDYARLLDDGCVDCFGRKDGQIKINGQRIETGEIE QRLLECSGIIEAVVVPYRVRETLHIAAVVCVNDSYDEVEVRGQLADRLPPFAIPESLVVV TEIAKSHSGKADLAQLRYLLPATQCNAVSTTISEVHSDMEHALHAIWQRVLDRQDIDSNA SFFALGGTSLDTIRVKGDIKRQLGLEIDITDLFKYPTLTALAHFLDTAVSPEDAIPTRAV VYSDMPVAIVGMAGRFPGAANIAALWTLVVGGESGLTLFSDEELRAHGVTPDTLKQANYI KTKGIVDDHEWFDADFFGYTPNEAECMDPQIRLLHQCCWQTLEHAGCDPATFTGAIGIYA GLLTSPHWLNAVMQDTTDSTALYKASILNIHSVTALIAHALNLTGPAVTLDTACSTSAVA IHQACIALRNRDCDAALAGGVSIEMPAYRGYEYHEGMINARDGVCRPFDSQASGTVTGDG LGMLLLKRLDDALADRDCIYGVIKGSAVNNDGNNKIGYTAPSVIGQSTVIRTSLRRAGFD SDSIGLVEAHGTGTVLGDPIELRALNEVFGPTPVPFCVVSALKSNIGHLNSAAGVAGVIK TTLALHHQVLPPTAHFRQLNPAIDLSRSALYVNQQVQPWPSTRPRRALVSSFGIGGTNAS IALEAHQHEDDPSATGVRDSYLLLFSAKTPAALELRVASTLEYVKHGVGVRLPDVAYTLQ TGRTAFDHRRAYLVSRGSKIDLSCATILQAEIFNGQRTTAEICFMFPGQGSQYHGMASAL YAHQPMFRQHMDRCFAAFQRYSTVDLKALLFDDEDTRDIDQTQFTQPALFCVEYSLARTL IDLGITPDSMIGHSLGEYVAACIAGVFTLEDALHVIEARGRLMQSMRPGSMMAVYLSREQ LTPWLAAERGIELAANNSAHFCVVAGEQAAISRLSTRLVEGGIQHRRLKTSHAFHSAMMT PMLHDFAQLLGQIPMHAPHKRFISNVSGTWITEEQATSPDYWVQQVRNAVLFSEGAAQLL VQPTLFIECGPGNTLSTFIQGHNQYSDQPTLLTLRKANAAIDDEHMLHRTLAALWVRGEN IDWRRFNQTALGKHIPLPDYPFEQTYYYRYGAALSGYRQYPNPLRRPQDEWLQRVLWRMH DTSLREAFYAPGELIIIISADGDKLQQTLMSSGVDSITMPLPISSEDDVWDNDRILTHFH DICALLAHKTYRQLHCLYAPGAEAGSSLTQSLSGLYRVARWCMHSTTPLASLTVLTHGAF RVQEEDNPEPTLAALSGAVNVFAQELHPTEVRLIDIDAQSSDENLNLLTQRLAPKQETVM ALRQGMLYLRRFIPTRLLAHLPPQTGCIPGNVLWIIGGEKGIGRMIGEALAQREGVRVVL SSRTGYHHEAVQQDALDVIHCDVTQAEAVRACLATLLERYGRLDGVIFAADATTTLTLHQ LSESALRDTLTVKERGTANVLHALAQRNLLDERLLLLFCNSLAAVNAEIGQTGYATASAY LDALAQQLRTRYKVNALSIGLDALREQGMLLDAINGSEYDVLRGLRPLMTGTLLQAYKQQ GADTSYYARLSPESDWLLDEHRISGIATLPGTGYLALAYEALRHYFVQDQICIDELVFLA PLTVMDNCSVDVFVDISPNGQGVSVEVKSMTERFSGTLTTHARGRATRLMVDDNVVCDLT GLMREMHTITPPTKELSSTHFHYGPRWHSVQQLYGNTAQTQVFATLALPTVAANDTIALH PALLDIASSVVEQLPGFHTDSVPFLYQDLRLYRPLPNTLHVALTVNRHDEEGDSYAFTLY DMAGEMVARCAAMVKRKVQLHIQDVDDDTRLRVPSADNYQLRLAAEGEGAGKLALCPTPR LALGDSQVEIEVLATGLNFKDVLFTTGLLRQQPGEAPLQLGLECAGRITRVGKNVTEFAP GEDVMAVLNGGFVQYARVESDCVVRKPAHCRIEQAAALPIAYLTAYYALVVRANLQPGER VLIHSAAGGVGLAALHIAKRCGAQIFATAGSEQKRDYLLSLGVHAVADSHDEQFAATLLT ASDGQGMDVILNSLTGRLLDASLALLAPLGRFLELGSKDIVEDKALPMRFFAQGGTFIPI NFHAAHGAFSRYLQQIVAWIDDNTLPLLPCKSVPLPEVARAFATLTTPQHIGKVVVTHRT AAGMDRLNAMIAERRLGGYALSMSNAEVMRQLWPILNTRSPWAQLLLSPRAIDRLARGNR VDRGVPSAANDTITQQTVKKRPRPEIGVPYSPATREVERVLCQILEEYLGLDRVGIDDNY AELGATSLDMVQLSGQMARHYPQVSVVSLYNHATVRQLATFCQPPEGESNAPSPQPAVQT NTRANQIAKRALQIAKNTARSHTSLH NT seq 9621 nt NT seq  +upstreamnt  +downstreamnt atggataatacctctggagattttccatgtaataagatggacacgcgtaagcagttaccg ctaacaccaagtcaacaggggtttttattccattccttaaaggataagaaaaggagtaac taccatgagcattttacatgcattttttctcagcatgtagatagcgcccacttcaagtgg gcgctggaaacgttatttcgaaagcatgagtgttttcgcactgattataactgggagatt gatgagcgcccttgtcaggtggtgaagaccgatgtgttgccggatatatatgtgttagac tgtgagcaagaggaaatacgttttctactagctaatgatgacattatcattcctgtcccg caggatgacggtattgatgctataattcctcaactgctacaggctgatttaaaataccca ttttccttgaaaacgatcccagtccgggcctaccttattcagtcaacgaaagaaagtgct tttatactatcataccatcatattgtgatggatggctggagcttatcccttttcattaaa cagttgctccaactctatggagcggctgtggtcagtggtgtgagggatgatagcgccatt atcccctcatctctgaaaccccttgtagacacactgtcggcccgacgtcacacctttcag cacgactattgggctgcatatcttcgggagggaacaccaacttgtatcgtgccgctgtca caatatcacacagatactgaagccgagaacaattcttacgttaatcaaacaaatcatgtg gagatcaatttgtctccggatgtgtgtcagaaaatacagacgctatgcagcgattatcgt atcacccccgcagtaatcttctatgtggcctggggcatcctgctacaacgttggtgctat gctgacgatgtgttattcggcgcgacaatatcagggcgaaatataccaattgatggtata gaagaaacactagggctatttattaacacgttgccgctgcgtctgcgtgatgatggggcg acactgttgcaacacttacaacgtatgcaccaaacactaatagctcactacagcaatgaa catgatgccttagccagcatacaacggttggtacataaagaaggtcatgctggggatctt tttaataccttagtggtgttggagaattatcccgttgatatgacattattgtcatgcgcg tcgcccgtggcaattcgccatctcagtgtacatgaacaaacgcactatccgctgaccttg accatcactcaacagaagggattccgtttcagtattgcatatgcccttaactacctgacc aacaacatggcgcaagcgttgctgatgcacctgagttatctgcttgaacaactggtggac aatccgcagcgccccattgctgcgttggtaaacttgtccccatgccagcaggcgcaggta cttcaaccctatctggaacgcatggcatgccgggattgggatagtcaatccaacgtcatc gaacaatttcatcaagttgctgcgacttcgccagcacaggttgcagtggttgatgaattg tgcgcgttgacctattcggagttggcagcacaagctgagcagctcgcggcttatttggta cagcagggtgttatggttggcgatactgtaggcataattagcgaacgccgggtaaacacc gtggttgccatcatcgccatcatgttgatcggggctgcttatgtgcccatcagccccgac tacccagtgggtaggatgcaggaaattattgatgacagcggcttggcgctgttgctggta catggcaaaccgctagatgcattaaacgttgcgcagagtgacctctgtgcatttcccgtc gcgccctcggtggtatttccggttatcacaccagattctcgcgcttatgtgatttattca tcggggtcgacgggtaagccaaaaggtatcgcggtggcgcaccgcggtttattgcgcctg atacaaggcgacagcccgctgaaggtggagagcggtgagacaacgctgctgacctgccca tttgagtttgatgtttcggtgtttgagatgtggtctaccttgctcaaccacggcaaacta gtattactcagcaaacaggcattacttgatatcaatcacattcgccgcacgatcgctgat gaacaggtggcgcgcgcctggtttacctcatccttgtttaactcctatgtggcagaaggt gccgatttcttcggtatgttacaacacattacggtgggcggcgaagcagtatctgcgtgg catgtcaacgacgtgatgcaaaaatacccgcatctggtggtgacaaacggttatgggccg acggaaaacactatttttaccaccgcatatcgtttcaacgggttgcaacccgcccgagtc ccgataggatacgcggtaccgggcacctcgctctacattaccgatctccatgggcatttg ttgcctatcggtgccaccggtgaactagtggcgggtggagtgggggtcgccatcggctat cagaacaacccggcgctaagtgcgacggtttttgtccctgatccttttattcccggcggt atgatgtacaaaactggcgattatgcccggttgctggatgatggctgtgttgactgtttt gggcgtaaagacggtcaaattaagatcaatggacaacgaattgaaaccggagagatcgag cagcgcctgctggagtgctccggcattatcgaggcggtagtggttccttaccgcgtacgt gaaacgctgcatattgcggcagtggtctgcgtcaatgatagctatgatgaggtggaagtt cgagggcaattggctgacagattgccgccattcgctattccggaatccttggtggtggtg acggagattgcaaaaagccatagtggcaaggccgacttggcgcagttgcggtatctcctg cccgcaactcagtgcaacgccgtgtccaccacgatatcagaggtgcatagtgacatggaa catgcgctgcatgctatctggcaacgcgtacttgatagacaagacattgatagcaatgcc tcctttttcgccctcggtggcacctcattggataccatcagggttaaaggggatattaag cggcaacttggcttggagattgatattaccgatctctttaagtacccaacgctcacggcg ttagcacattttctcgatactgccgtatcgccggaggatgcaattccaacgcgtgctgtt gtctacagcgacatgccggtggcgattgtcggtatggcgggacgtttccccggtgcggcg aatattgcagcgttgtggacgctggttgtaggaggggaatcgggattaacactgttcagt gatgaagagttgcgcgcgcatggtgtgacacctgacacgcttaaacaagcgaattatata aaaaccaaagggattgttgatgatcacgaatggtttgatgcggatttctttggttatact cccaacgaggcggaatgtatggatccgcaaattcgcttattgcatcagtgctgctggcaa actctggaacacgctgggtgcgatcctgccacctttactggtgcgattggcatttatgcc ggactgctgacatccccccactggcttaatgcggtaatgcaagacactaccgactctacc gccctgtacaaggccagtatcctgaatatccattccgtcacagcattgattgcccatgcg cttaacctcaccggccctgccgtgacgcttgacaccgcctgctccacttcggcagtggct atccaccaggcctgcatcgcactacgtaaccgggattgcgatgcggcattggcgggcggc gtttctatcgagatgcctgcgtaccggggctatgaatatcatgaaggcatgatcaatgcg cgagatggtgtctgtcgtcctttcgatagccaagcctctggcacagtcaccggtgatggc ttaggaatgctgctgctaaaacgtctggacgacgcgctggcggatcgggactgcatctat ggtgtgatcaaaggttcggcggtcaataatgatggcaataacaaaatcggctataccgcg ccgagtgtgatcgggcaatcaacggtaatccgcaccagtttgcgccgtgccggttttgat agcgacagtatcggattggtggaagcgcacggcaccggtacggtgctgggtgatcctatt gagttacgtgcgcttaatgaggtgtttggcccaacacctgttccgttttgtgtggtttca gcgctgaaaagtaatattggccacctcaactccgctgcgggagtggcgggcgtcatcaaa acaacgctcgccctgcatcatcaagtgttgccaccaacagcgcactttcgccaactcaat cctgctatagatctatcgcgttctgcattgtacgttaaccagcaagtccaaccgtggccg tcgacgcgtcctcgtcgtgcactggtgagctccttcggcatcggcggcaccaatgccagc atcgcactagaagcacatcaacatgaggacgacccttcagcgacgggggtacgcgacagc tatctgttgttgttctccgctaaaacacccgctgcgttagagttgcgcgtggcctccaca ctggaatatgtcaagcatggagtaggggtgcgcctgccggatgtggcttatacattgcaa actggacgcacagcctttgaccatcggcgggcttatttggtgagtcgtgggtcgaaaatc gatctctcctgtgccacgatattgcaagcggaaatcttcaatggtcagcgcacgacagcg gagatctgcttcatgtttcctggtcaaggtagccaatatcacggcatggccagcgcgctc tatgctcatcaacccatgtttcgccagcacatggatcgctgctttgctgcattccaacgc tattcgacggtcgatctcaaggcgttgttgtttgacgatgaggatacgcgggatattgat caaacgcagttcacacaaccggcgttgttctgtgtcgaatacagcctagcgcgcaccttg attgatctggggattacgccggacagtatgatcgggcacagtctgggcgagtatgttgcg gcctgtattgctggcgtatttactcttgaggatgcgctgcacgtcattgaggcgcgcgga cgtttgatgcagtccatgcgtcccggtagcatgatggcggtctaccttagtcgcgaacag ttgaccccatggctagctgcagaacggggtattgaactggcagctaataatagcgcgcat ttttgcgtagtcgcgggcgagcaggcggccatttcccgtttgagcacacgcttagtcgag ggcgggatacagcacaggcgcctgaaaacctctcacgcattccactcggccatgatgacg ccgatgctgcacgattttgcacagttgctggggcaaatcccgatgcacgcgccgcacaag cgctttatatctaatgtaagcggtacatggattactgaggagcaagctacctcgccggat tactgggtgcagcaagtgcgcaacgcggtgctgtttagcgaaggtgcggcgcaactgttg gtacaacccacgctgtttatcgaatgtgggccgggtaatacgctctctacctttattcaa ggacataaccaatacagcgatcagccgaccctgttgacgctacgcaaagccaacgcggcg atcgatgatgagcacatgttgcatcgtacgctggcggcgctgtgggtcaggggggagaat attgattggagacgctttaaccagacggcactcggcaagcacattccattgccggattac cccttcgaacagacttattactatcgctatggtgctgcactttccggttatcgccagtat ccaaatcctctgcgccgtccgcaagatgagtggctccagcgtgtgctgtggcggatgcac gacacatccttgcgggaggcgttctatgcgccgggcgaattgatcatcattattagtgct gacggcgacaagttacagcagacgctgatgagtagtggtgtcgacagcatcacaatgccg ctgccgatatcgtcagaggacgacgtgtgggataatgaccgtattctgacgcatttccac gacatctgcgcacttttagcacacaaaacctaccgacagttacattgcttgtatgctccc ggtgcggaggcaggatcatcgttgacacagtcgctctcgggactttatcgtgttgctcgc tggtgtatgcacagcaccacgccgctggcgtccttaacagtattgacccatggtgcgttt cgcgtacaggaagaggataatcccgaaccgacgctggcagcgttgtcgggcgcagtaaac gtgtttgcccaagagctgcacccgaccgaagtacgattgatcgatatcgatgcgcagagc agtgatgagaatctgaacttgctaacccagcgtctggccccgaaacaagaaacggtaatg gcgctcaggcaggggatgctttacctgcgacgctttatcccgacacggctgttggcgcac ttaccccctcaaacagggtgtataccgggcaacgtactgtggattatcggcggtgaaaag gggattggccgcatgatcggcgaagcgcttgctcagcgtgagggagtccgtgtggtactg agcagccgcacaggttatcaccatgaagcggtgcagcaggacgcattagacgttatccac tgcgacgtgacgcaggcggaggcggttagagcttgtctggcaactctgctcgaacgctat ggacggttggatggcgtgatttttgctgccgacgctaccaccacattgacactgcatcaa ttgagcgaatctgcgctacgcgacacgctaacggtgaaagaacggggtactgctaatgtg ctgcatgcgttagcgcaacggaatctgctggatgagcgtctgctactgctgttctgtaac tcgttggctgccgtgaatgcggagattggccagacaggctatgctaccgccagcgcctat ttggatgcactggcacagcaactgcgtacccgctacaaggtgaatgcgctcagtatcggg ttggatgcattgcgtgagcagggcatgttgttggatgctataaacggcagtgaatacgat gtcttgcgtggactgcgcccattgatgacgggaacgttgctacaggcttataaacaacaa ggggctgacaccagctactacgcgcgattatcccccgagtccgattggctgctggatgag caccggatatccggtatcgccacgctgccgggaaccggctatctggcgctggcgtatgaa gctctgcgccattactttgtgcaagaccaaatctgcattgatgaattggtctttttggca ccgttgactgtgatggacaactgcagtgttgacgtttttgttgacatttcacctaacggg caaggagttagtgtcgaggtgaaatcaatgacggagcgctttagtggcacgttaacaacc catgccagaggcagggcgacgcgtctgatggtagacgataatgttgtgtgcgatctcacg gggctgatgcgcgagatgcacactatcactcctccaacaaaggaattatcgagcacgcac ttccactatgggccgcgctggcacagcgtacaacaactgtatggcaataccgcccagact caggttttcgcaacgctggccctgcccaccgttgccgctaatgatacgatcgcactgcac cctgcgctgttggacatcgccagcagtgttgtcgaacaactgcctggttttcatactgat tcggtacctttcctttatcaggatttacgcctgtaccgcccgttgccgaacaccttacat gtggcgctgactgtcaatcggcacgatgaggagggtgacagctacgctttcacgctctac gacatggcaggcgagatggttgcccgctgtgcggcaatggtgaagcgcaaggtacagctc cacatacaagatgtcgatgacgacacgcgactgcgcgtgcccagtgccgataactaccaa ctgcggctggccgctgagggggagggggcaggaaagctagcgttgtgccctacgccgcgc ttagcgctgggggattcacaagtagagattgaggtactggccaccggactgaactttaag gatgtgctgttcaccacgggattgctccggcagcagccgggtgaggctccgctgcaattg ggactggagtgcgccggacgcattactcgcgtgggtaaaaatgtcactgaatttgccccg ggagaggatgttatggcggtgctaaacggtggttttgtccagtacgcacgggtagaaagc gattgcgtagtgagaaaaccagcccattgtcgcatcgaacaggcggctgcgctgcctatc gcatacctcaccgcctattacgcactggtggtgcgcgctaatttgcaacccggagaacga gtattgatccacagtgcggcggggggcgttggcttggctgcgctacatattgccaaacgc tgcggagcacagattttcgccacagcaggtagcgagcagaaacgcgattacttgctttcg ctaggcgtacatgccgtagctgattcacacgacgaacagttcgctgccactctgctgacc gcatcggacggacaggggatggatgtgatccttaactccctcacaggccgtctgcttgac gctagcctcgcgctgctggcaccgctgggccgttttcttgagctgggcagcaaggacatt gtggaagacaaagcgctaccgatgcgtttcttcgcccaaggcggcacctttattccgatt aattttcacgcggcgcatggtgcgtttagtcgctacctgcaacagattgtcgcttggata gatgataacacgctaccgctccttccatgcaaatccgtaccattgcccgaggttgcacgc gccttcgccaccctgaccacgccgcagcatattggcaaggtggtggtaacgcatcgcact gcggcaggcatggaccggctgaacgccatgatagcagaaaggcgcctcggcggctatgcg ctcagcatgagcaatgccgaggtgatgcgccaattgtggccgatactgaacactcgcagt ccgtgggcgcaactgctgctctcacctcgggcgatcgatagattagcgcggggcaaccgg gtggatcgcggtgtaccgtctgccgctaacgatacgattactcagcagacagtgaaaaag cggccccgtccggaaattggcgtgccttacagccccgcgacacgtgaagtggaacgcgtg ctctgccaaatcctggaagagtatctgggtctggatagagtaggcattgacgacaactat gccgaattaggggcaacctcactcgatatggtgcaactgagtgggcaaatggcgcgtcac tatccgcaagtgagcgtggtgtcgctgtacaaccacgccaccgtgcgccagctggcgacg ttttgccagcccccggagggcgagtcaaatgcgccatcaccacagcctgcagtacagacg aatacgcgcgcgaatcagatagcaaaacgtgctttgcaaattgcgaaaaatactgcgcgc agtcacacgtctttgcattaa

DBGET integrated database retrieval system