Escherichia coli JJ1886: P423_22140
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Entry
P423_22140 CDS
T02896
Name
(GenBank) phosphomethylpyrimidine synthase ThiC
KO
K03147
phosphomethylpyrimidine synthase [EC:
4.1.99.17
]
Organism
ecoj
Escherichia coli JJ1886
Pathway
ecoj00730
Thiamine metabolism
ecoj01100
Metabolic pathways
ecoj01240
Biosynthesis of cofactors
Module
ecoj_M00127
Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
Brite
KEGG Orthology (KO) [BR:
ecoj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
P423_22140
Enzymes [BR:
ecoj01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.17 phosphomethylpyrimidine synthase
P423_22140
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Gene cluster
GFIT
Motif
Pfam:
ThiC_Rad_SAM
ThiC-associated
Motif
Other DBs
NCBI-ProteinID:
AGY86625
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Position
complement(4550202..4552097)
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AA seq
631 aa
AA seq
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MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSK
EQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKA
RLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARKGIITPEMEFIAIRENMGRERIRSEV
LRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQAL
EKVNGIAEDLTWEVFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMA
KWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELT
KIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAM
SKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDY
AAAQTIEVGMADMSENFRARGGEIYLRKEEA
NT seq
1896 nt
NT seq
+upstream
nt +downstream
nt
atgtctgcaacaaaactgacccgccgcgaacagcgcgcccaggcccaacattttatcgac
accctggaaggctccgcctttcccaactcaaaacgcatttacatcactggcacacacccc
ggcgtgcgcgtgccgatgcgtgagatccagcttagcccgacgctaattggcggcagcaaa
gaacagccgcagtacgaagaaaacgaagcgattccggtctacgacacctccggcccgtat
ggcgatccgcagattgccattaacgtgcagcaagggctggcaaaactacgccagccgtgg
atcgatgcgcgcggcgataccgaagaacttaccgtacgcagttccgattacactaaagcg
cggctggcagatgatggccttgacgagctgcgttttagcggcgtattaacgccaaaacgc
gccaaagcaggacgccgcgtcacccaactgcactacgcccgcaagggtatcatcacgcca
gaaatggaattcatcgccattcgcgagaatatgggtcgcgagcgcatacgtagcgaagtt
ttacgccaccagcatccgggaatgagctttggcgcacgtctgccggaaaatatcactgcg
gaatttgtccgtgatgaagttgctgccggacgtgcgattatcccggccaacattaatcat
ccggaatcggagccgatgattattggccgtaacttcctggtaaaagttaacgccaatatc
ggcaactcggcggtcacttcttccatcgaagaagaagtggaaaaactggtatggtccacg
cgctggggagcggataccgtgatggatctttccactggtcgctatattcacgaaacccgc
gagtggattttgcgtaacagcccggtgccgatcggtacagtgccgatctaccaggcactg
gagaaggtgaacgggatcgctgaagatcttacctgggaagtcttccgcgacaccctgctg
gaacaagccgagcaaggtgtggattacttcactatccatgcgggggtgctgctgcgctac
gtgccgatgaccgcgaaacgcctgaccggtatcgtctctcgcggcggttcgattatggcg
aaatggtgcctctcccatcatcaggaaaatttcctctatcaacacttccgcgaaatttgt
gaaatctgtgctgcttatgacgtttcgctgtcgctgggcgacggcctgcgccccggttct
attcaggacgccaacgatgaagcacagtttgccgagctgcatacgctgggcgaactgacc
aaaatcgcctgggaatatgacgtgcaggtgatgattgaaggcccaggccacgtgccgatg
cagatgattcgccgcaatatgaccgaggagttagagcactgccacgaagcgccgttttac
actctggggccgctaactaccgatatcgcgccgggctatgaccacttcacgtcagggatt
ggcgcggcgatgattggctggtttggctgcgcgatgctctgctacgtaacgccgaaagag
catctgggcctgccaaataaagaagatgttaaacaggggcttatcacctataagattgcc
gctcacgccgccgacctggcgaaagggcatccgggcgcgcaaattcgcgataacgccatg
tcgaaagcccgcttcgaatttcgctgggaagaccagtttaatctggccctcgacccgttt
actgcccgcgcttatcacgatgaaaccctgccgcaagagtccggtaaagtcgcccatttt
tgctccatgtgtggaccgaaattctgctcgatgaaaatcagccaggaagtgcgtgattac
gccgccgcgcaaaccattgaagtgggaatggcggatatgtcggagaacttccgcgccaga
ggcggagaaatctacctgcgtaaggaggaagcgtga
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