Escherichia coli K-12 MDS42: ECMDS42_0281
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Entry
ECMDS42_0281 CDS
T02541
Symbol
ddlA
Name
(GenBank) D-alanine-D-alanine ligase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
ecok
Escherichia coli K-12 MDS42
Pathway
ecok00470
D-Amino acid metabolism
ecok00550
Peptidoglycan biosynthesis
ecok01100
Metabolic pathways
ecok01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ecok00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
ECMDS42_0281 (ddlA)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECMDS42_0281 (ddlA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ECMDS42_0281 (ddlA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
ecok01011
]
ECMDS42_0281 (ddlA)
Enzymes [BR:
ecok01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
ECMDS42_0281 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:
ecok01011
]
Precursor biosynthesis
Amino acid ligase
ECMDS42_0281 (ddlA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATPgrasp_ST
ATP-grasp_4
RimK
GARS_A
Motif
Other DBs
NCBI-ProteinID:
BAL37589
LinkDB
All DBs
Position
complement(307572..308666)
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AA seq
364 aa
AA seq
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MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGIDKQGQWHVSDASNYLLN
ADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVIFPIVHGTLGEDGSLQGML
RVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFITLTRANRHNISFAEVESKLGL
PLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKVIVEQGIKGREIECAVLGNDNPQ
ASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAPEINDKIRAIAVQAYQTLGCAGMAR
VDVFLTPENEVVINEINTLPGFTNISMYPKLWQASGLGYTDLITRLIELALERHAADNAL
KTTM
NT seq
1095 nt
NT seq
+upstream
nt +downstream
nt
atggaaaaactgcgggtaggaatcgtttttggtggtaaatcagcggaacatgaagtgtct
ctgcaatcggcaaaaaacattgtcgatgccattgataaaagtcgcttcgacgttgtgctg
ctgggcattgataaacaagggcaatggcacgtcagcgatgccagcaattatctgctaaat
gcagacgatcctgcccatattgcgttgcgcccttcggcgaccagccttgcgcaggtgcca
ggtaaacatgagcatcagcttatcgacgcgcaaaacggtcagccgttgccgacggtggat
gtcattttcccgattgtccacggtacgctgggcgaagatggttccttgcagggaatgctg
cgggtcgccaatttaccgtttgtaggttctgatgttctggcttcagcagcctgtatggac
aaagatgtcaccaaacgtctgctacgcgatgccgggctgaacattgcgccatttattacc
ctgacgcgcgccaatcgtcacaacattagttttgccgaagtggagtctaaactggggtta
ccactgtttgtaaaaccggctaatcagggctcttctgttggtgtcagcaaagtaaccagt
gaagaacagtacgcaattgccgtcgatctggcgttcgagttcgatcataaagtgatcgtt
gagcaagggatcaaaggtcgtgagatcgaatgcgcagttctgggcaacgacaatccgcaa
gccagcacctgtggagagatcgtactcaccagcgatttctatgcctacgacaccaagtac
attgacgaagatggcgcgaaagtggtagttccggcagccattgcgccagaaatcaacgat
aagatccgggcgattgccgttcaggcttatcaaacgttgggatgcgcaggcatggcgcgt
gtagacgtgtttttaaccccagagaacgaagtggtgatcaacgagatcaacaccctgcct
ggcttcactaatatcagtatgtatccgaagctgtggcaagccagcggtctgggttacacc
gatctgatcacacgtttgattgaactggcgctggagcgtcacgctgcggataacgcattg
aaaaccacaatgtaa
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