Escherichia coli O25b K100 H4-ST131 EC958 (UPEC): EC958_0212
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Entry
EC958_0212 CDS
T04373
Symbol
leuC
Name
(GenBank) 3-isopropylmalate isomerase (dehydratase) subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ecos
Escherichia coli O25b:K100:H4-ST131 EC958 (UPEC)
Pathway
ecos00290
Valine, leucine and isoleucine biosynthesis
ecos00660
C5-Branched dibasic acid metabolism
ecos01100
Metabolic pathways
ecos01110
Biosynthesis of secondary metabolites
ecos01210
2-Oxocarboxylic acid metabolism
ecos01230
Biosynthesis of amino acids
Module
ecos_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ecos00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
EC958_0212 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EC958_0212 (leuC)
Enzymes [BR:
ecos01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
EC958_0212 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
EC958_0212 (leuC)
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Motif
Pfam:
Aconitase
Spo0M
Motif
Other DBs
NCBI-ProteinID:
CDN80448
UniProt:
A0AA36KU60
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Position
complement(88285..89685)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaagacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccacc
atggatcacaacgtctctacccagacgaaagacattaatgcctgcggtgaaatggcgcgc
atccagatgcaggagctgatcaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggtgtgaccttgccg
gggatgaccattgtctgcggcgactcacataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgggcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattattggtaaaaccggcagcgcaggcggtaccgggcatgtg
gtggaattttgcggcgaagcaatccgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcaatcgaaatgggcgcaaaagccggtctggttgcgccggacgaaaccaccttt
aactatgttaaaggccgtctgcatgcgccgaaaggtaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggagcaactttcgataccgttgtcactctgcaa
gcagaagagatttcgccgcaggtcacctggggcaccaatccaggccaggtgatttctgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggtattccgctgacagaagtggctatcgac
aaagtgtttattggttcctgtactaactcgcgtattgaagatttacgcgcggcagcggaa
atcgccaaaggccggaaagtcgcgccaggcgtacaagcgctggtggttcccggctccggt
ccggttaaagcccaggcggaagcggaaggtctggacaaaatttttatcgaagctggtttt
gaatggcgcttgccaggttgctcaatgtgtctggcgatgaataacgaccgtctgaatccg
ggcgaacgttgcgcctccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgccgcggctgtgaccggacatttcgcc
gacattcgtaacattaaataa
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