Escherichia coli O25b K100 H4-ST131 EC958 (UPEC): EC958_2863
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Entry
EC958_2863 CDS
T04373
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ecos
Escherichia coli O25b:K100:H4-ST131 EC958 (UPEC)
Pathway
ecos00230
Purine metabolism
ecos01100
Metabolic pathways
ecos01110
Biosynthesis of secondary metabolites
Module
ecos_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecos00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
EC958_2863 (purL)
Enzymes [BR:
ecos01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
EC958_2863 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CDN83200
UniProt:
A0AA36P890
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Position
complement(2863312..2867196)
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AA seq
1294 aa
AA seq
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MEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLNAPLNDDEHAQLERLLKY
GPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGMAYYIEAGTLTN
EQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGLA
LAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKMI
KNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPTA
ISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVT
ALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIR
ADHVQKDEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRC
QEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLE
IWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLP
LDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVT
GMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALT
NIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSM
KTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGAT
ALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAG
HCGIDADIASLGDDRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVSG
DRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKL
SFDINEDVAAPFIATGVRPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTG
LEGFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMM
SNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRV
EVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHP
ERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
atggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctggca
cgttttcaggctgccaggctcccggttcacactatttacgccgagtatgtccattttgct
gacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaatat
ggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgtcct
ggcaccatctctccctggtcttcgaaagcgaccgatatcgcccataattgcggtctacaa
caggtaaaccgccttgagcgcggcatggcttactatatagaagccggtacgctgaccaat
gaacaatggcagcaggtgaccgctgaactgcacgaccgcatgatggaaacggtctttttt
gctttagatgatgcagagcagttgtttgcacaccatcaaccgactccggtcaccagcgta
gatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctggca
ctggcggaagatgaaattgactatctgcaggatgcgttcacaaagctgggtcgtaacccg
aacgacatcgagctgtatatgttcgcgcaggcgaactccgagcactgccgtcacaaaatt
tttaacgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaagatgatc
aaaaacaccttcgaaaccacgccagaccacgttctctctgcttataaagataacgccgct
gtaatggaaggttctgaagtgggtcgctactttgctgaccacgaaacgggccgctacgat
ttccatcaggaaccggcgcatattctgatgaaagttgaaacccacaaccacccgacggcg
atttctccgtggccgggtgcggcgaccggttctggcggtgaaatccgcgatgaaggtgcc
accgggcgcggcgcaaagccgaaagccggtctggttggtttctccgtatccaacttgcgt
attccgggctttgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtcacc
gcgctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaatttggt
cgcccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaatggc
gaagagctgcgcggttatcacaaaccgatcatgctggcgggtgggatcggcaacattcgc
gccgatcacgtacaaaaagacgagatcaacgttggtgcgaagctggtcgttctcggcggc
ccggcaatgaacatcggtcttggcggcggcgcggcgtcttccatggcatctggtcagtct
gatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgctgc
caggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatccac
gacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcgggcgc
ggcggtaaattcgaactgcgcgatattctgagcgacgagccaggcatgagcccgctggaa
atctggtgtaacgaatcccaggaacgctacgtgctggcagttgctgccgatcagttaccg
ctgtttgacgaactgtgtaagcgtgaacgcgcaccgtacgcggtgattggtgaagcgacc
gaagaactgcatctttctctgcacgatcgtcattttgataatcagccgattgatctaccg
ctggacgtactgcttggcaaaacgccgaagatgacccgcgatgtgcaaacgctgaaagcg
aaaggcgacgcgctggcccgtgaagggatcaccatcgctgacgcggtgaaacgcgtgctg
catctgccgaccgtggcggagaaaactttcctggtgaccatcggtgaccgcagcgtaacc
ggcatggtggcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgcgcg
gtcactaccgccagcctcgacagctactatggcgaagcgatggcaattggcgaacgtgcg
ccagttgcgctgctggatttcgccgcttctgcccgtctggcagtcggtgaagcgctaacc
aacatcgccgcaacacaaattggcgatatcaaacgcattaaactttccgccaactggatg
gcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtgggc
gaagaactttgtccggcgctgggcctgacgataccggtgggtaaagactctatgtcgatg
aaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgttgtcgctggtg
atttccgcatttgcccgcgtggaagatgtacgtcacaccattacgccgcagctttctacc
gaagataacgcactgttgctgattgatttgggcaaaggcaataacgcgctgggcgcaacg
gcactggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgttgcc
caactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctggcg
tatcacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgctggt
cattgtggcattgacgcggatatcgcctctctgggtgacgatcgcctggcggcgttgttt
aacgaagaactgggtgcggtgattcaggttcgagctgctgatcgtgaagccgttgaagcg
gtactggcacagcatgggcttgctgattgcgtccattatgttgggcaggcggtttccggt
gaccgttttgtgattactgccaacgggcagactgtatttagcgaaagccgcaccacgctg
cgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggagtgt
gccgatcaggaacaccaggcgaaatcaaacgacgccgatccgggcctgaatgtgaaactg
tcgtttgatatcaacgaagatgtggcagcaccgtttattgccactggcgtgcgcccgaaa
gttgccgtgctgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttccac
cgtgcaggcttcgatgctatcgacgtgcatatgagcgatctgctggctggacgcacgggc
ctggagggtttccacgccctggtcgcgtgtggtggtttctcctacggtgatgtgctgggc
gctggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagtttgca
accttcttccatcgtccgcaaacgctggcgctgggggtatgtaacggttgccagatgatg
tctaatctgcgtgaactgatcccgggtagcgagttgtggccacgttttgtgcgtaacacc
tccgatcgctttgaagcgcgtttcagtctggtagaagtaacccaaagcccgtcgctgctg
ttgcaggggatggtgggctcgcagatgccgattgctgtgtctcatggtgaagggcgcgtg
gaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactgcgc
tatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttcaccg
aacggtattacggcggtcacgactgaaagtggtcgagtcaccattatgatgccgcacccg
gaacgagttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggatggc
ccatggatgcgcattttccgcaatgcacgtaagcagttggggtaa
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