Escherichia coli O25b K100 H4-ST131 EC958 (UPEC): EC958_2956
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Entry
EC958_2956 CDS
T04373
Symbol
gshA
Name
(GenBank) gamma-glutamate-cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ecos
Escherichia coli O25b:K100:H4-ST131 EC958 (UPEC)
Pathway
ecos00270
Cysteine and methionine metabolism
ecos00480
Glutathione metabolism
ecos01100
Metabolic pathways
ecos01240
Biosynthesis of cofactors
Module
ecos_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ecos00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
EC958_2956 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
EC958_2956 (gshA)
Enzymes [BR:
ecos01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
EC958_2956 (gshA)
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Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
CDN83291
UniProt:
A0AA36P7T4
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Position
complement(2955900..2957456)
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGY
FRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALA
DAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTL
DSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL
EILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgtgggctggagcgcgaaactttgcgtgttaatgctgatggcacactggca
acaacaggtcatcctgaagcattaggttctgcactgacccataaatggattactaccgat
tttgcggaagcattgctggaatttattacaccagtggatggtgatattgaacatatgctg
acctttatgcgcgatctgcatcgctatacggcgcgcaatatgggcgatgagcggatgtgg
ccgttaagtatgccatgctacatcgcagaaggtcaggacatcgaactggcacagtacggc
acttctaacaccggtcgctttaaaacgctgtaccgtgaagggctgaaaaatcgctacggc
gcgctgatgcaaaccatttccggcgtgcactataatttctctttgccaatggcattctgg
caggcgaagtgcggtgatatctcgggcgctgatgccaaagagaaaatttctgcgggttat
ttccgcgttatccgtaactactatcgcttcggttgggtcattccttatctgtttggtgcg
tctccagcgatttgttcttctttcttgcaaggaaaaccaacgtcgctgccgtttgagaaa
accgagtgcggtatgtattacctgccgtatgcgacctctcttcgtttgagcgatctcggc
tataccaataaatcgcaaagcaatcttggtatcaccttcaatgatctctacgagtacgtg
gcgggccttaaacaggcaatcaaaacgccatcggaagagtacgcgaagattggtattgag
aaagacggtaagcggctgcaaatcaacagcaatgtgctgcagattgaaaacgaactgtac
gcgccgattcgtccaaaacgcgttacccgcagtggtgagtcgccttctgatgcgctgtta
cgtggcggcattgaatatattgaagtccgctcgctggacatcaacccgttctcgccgatt
ggtgtagatgaacaacaggtgcgattcctcgacctgtttatggtctggtgtgcgctggct
gacgcaccggaaatgagcagtagcgaacttgcctgtacacgcgttaactggaaccgggtg
atcctcgaaggtcgcaaaccgggcctgacgctgggtatcggctgcgaaaccgcgcagttc
ccgttaccgcaggtgggtaaagatctgttccgcgatctgaaacgcgtcgcgcaaacgctg
gatagcattaacggcggcgaagcgtatcagaaagtgtgtgatgaactggtcgcctgcttc
gataatcccgatctgactttctctgcccgtatcttaaggtctatgattgatactggtatt
ggcggaacaggcaaagcgtttgctgaagcgtaccgtaatctgctgcgtgaagagccgctg
gaaattctgcgcgaagaggattttgtcgccgagcgcgaggcgtctgaacgccgtcagcag
gaaatggaagccgctgataccgaaccgtttgcggtgtggctggaaaagcacgcctga
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