Escherichia coli O8 IAI1 (commensal): ECIAI1_0116
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Entry
ECIAI1_0116 CDS
T00828
Symbol
acnB
Name
(GenBank) bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
ecr
Escherichia coli O8 IAI1 (commensal)
Pathway
ecr00020
Citrate cycle (TCA cycle)
ecr00630
Glyoxylate and dicarboxylate metabolism
ecr00640
Propanoate metabolism
ecr00720
Other carbon fixation pathways
ecr01100
Metabolic pathways
ecr01110
Biosynthesis of secondary metabolites
ecr01120
Microbial metabolism in diverse environments
ecr01200
Carbon metabolism
ecr01210
2-Oxocarboxylic acid metabolism
ecr01230
Biosynthesis of amino acids
Module
ecr_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ecr_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
ecr_M00012
Glyoxylate cycle
ecr_M00982
Methylcitrate cycle
Brite
KEGG Orthology (KO) [BR:
ecr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ECIAI1_0116 (acnB)
00630 Glyoxylate and dicarboxylate metabolism
ECIAI1_0116 (acnB)
00640 Propanoate metabolism
ECIAI1_0116 (acnB)
09102 Energy metabolism
00720 Other carbon fixation pathways
ECIAI1_0116 (acnB)
Enzymes [BR:
ecr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
ECIAI1_0116 (acnB)
4.2.1.99 2-methylisocitrate dehydratase
ECIAI1_0116 (acnB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CAQ97005
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Position
131810..134407
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AA seq
865 aa
AA seq
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MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA
AYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESNRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDT
YRYLNFNQLSQYTEKADGVIFQTAV
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgctgaggggattgcgcccaaa
cccctggatgcaaaccaaatggccgcacttgtagagctgctgaaaaacccgcccgcgggc
gaagaagaattcctgttagatctgttaaccaaccgtgttcccccaggcgtcgatgaagcc
gcctatgtcaaagcaggcttcctggctgctatcgcgaaaggcgaagccaaatcccctctg
ctgactccggaaaaagccatcgaactgctgggcaccatgcagggtggttacaacattcat
ccgctgatcgacgcgctggatgatgccaaactggcacctattgctgccaaagcactttct
cacacgctgctgatgttcgataacttctatgacgtagaagagaaagcgaaagcaggcaac
gaatatgcgaagcaggttatgcagtcctgggcggatgccgaatggttcctgaatcgcccg
gcgctggctgaaaaactgaccgttaccgtcttcaaagtcactggcgaaactaacaccgat
gacctttctccggcaccggatgcgtggtcacgcccggatatcccactgcacgcgctggcg
atgctgaaaaacgcccgtgaaggtattgagccagaccagcctggtgttgttggtccgatc
aagcaaatcgaagctctgcaacagaaaggtttcccgctggcgtacgtcggtgacgttgtg
ggtacgggttcttcgcgtaaatccgccactaactccgttctgtggtttatgggcgatgat
attccacatgtgccgaacaaacgcggcggtggtttgtgcctcggcggtaaaattgcaccc
atcttctttaacacgatggaagacgcgggtgcactgccaatcgaagtcgacgtctctaac
ctgaacatgggcgacgtgattgacgtttacccgtacaaaggtgaagtgcgtaaccacgaa
accggcgaactgctggcgaccttcgaactgaaaaccgacgtgctgattgatgaagtgcgt
gctggtggccgtatcccgctgattatcgggcgtggcctgaccaccaaagcgcgtgaagca
cttggtctgccgcacagtgatgtgttccgtcaggcgaaagatgtcgctgagagcaatcgc
ggcttctcgctggcgcaaaaaatggtaggccgtgcctgtggcgtgaaaggcattcgtccg
ggcgcgtactgtgaaccgaaaatgacttctgtaggttcccaggacaccaccggcccgatg
acccgtgatgaactgaaagacctggcgtgcctgggcttctcggctgacctggtgatgcag
tctttctgccacaccgcggcgtatccgaagccagttgacgtgaacacgcaccacacgctg
ccggacttcattatgaaccgtggcggtgtgtcgctgcgtccgggtgacggcgtcattcac
tcctggctgaaccgtatgctgctgccggataccgtcggtaccggtggtgattcccatacc
cgtttcccgatcggtatctctttcccggcgggttctggtctggtggcatttgcagccgca
acaggcgtaatgccgctggatatgccggaatccgttctggtgcgcttcaaaggcaaaatg
cagccgggcatcaccctgcgcgatctggtacatgccattccgctgtatgcgatcaaacaa
ggtctgctgaccgttgagaagaaaggcaagaaaaacatcttctctggccgcatcctggaa
attgaaggtctgccggatctgaaagttgagcaggcatttgaactgaccgatgcgtccgcc
gagcgttctgccgctggttgtaccatcaagctgaacaaagaaccgatcatcgaatacctg
aactctaacatcgtcctgctgaagtggatgatcgcggaaggttacggcgatcgtcgcacc
ctggaacgtcgtattcagggcatggaaaaatggctggcgaatcctgagctgctggaagcc
gatgcagatgctgaatacgcggcagtgatcgacatcgatctggcggatattaaagagcca
atcctctgtgcaccgaacgacccggatgacgcgcgtccgctgtctgcggtacagggtgag
aagatcgacgaagtatttatcggttcctgcatgaccaacatcggtcacttccgtgctgcg
ggtaaactgctggacgcgcacaaaggccaactgccgacccgcctgtgggtggcaccgcca
acccgtatggacgccgcgcagttgactgaagaaggctactacagcgtcttcggtaagagt
ggtgcgcgtatcgagatcccgggctgttctctgtgtatgggtaaccaggcgcgtgtagca
gacggtgcgacggtggtttccacctctacccgtaacttcccgaaccgtctgggtactggc
gcgaatgtcttcctggcttctgcggaactggcggctgttgcggcgctgattggcaaactg
ccgacgccggaagagtaccagacctacgtggcgcaagtagataaaactgccgttgatact
tatcgttatctgaacttcaaccagctttctcagtacaccgaaaaagccgatggggtgatt
ttccagactgcggtgtaa
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