Escherichia coli O8 IAI1 (commensal): ECIAI1_2342
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Entry
ECIAI1_2342 CDS
T00828
Symbol
menD
Name
(GenBank) bifunctional 2-oxoglutarate decarboxylase and SHCHC synthase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
ecr
Escherichia coli O8 IAI1 (commensal)
Pathway
ecr00130
Ubiquinone and other terpenoid-quinone biosynthesis
ecr01100
Metabolic pathways
ecr01110
Biosynthesis of secondary metabolites
ecr01240
Biosynthesis of cofactors
Module
ecr_M00116
Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol
Brite
KEGG Orthology (KO) [BR:
ecr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
ECIAI1_2342 (menD)
Enzymes [BR:
ecr01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
ECIAI1_2342 (menD)
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Motif
Pfam:
TPP_enzyme_M_2
TPP_enzyme_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
CAQ99184
UniProt:
B7M5U7
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Position
complement(2424534..2426204)
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AA seq
556 aa
AA seq
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MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSTFIHHTHFDERGLGH
LALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAI
RQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHVGGVHINCPFAEPLYGEMDD
TGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALW
AQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQAS
CEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAV
IARRDAFGEAQLAHRICDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDG
LLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPT
PQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDT
DGAQTLQQLLAQVSHL
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgtcagtaagcgcatttaaccgacgctgggcggcggtcattctggaagcattaacgcgt
cacggcgtcagacacatctgtatcgcccctggctcgcgttctacaccgttaacgttagcg
gcggcggagaattccacattcattcaccacacccatttcgatgagcgtggactgggacat
ctggcgctggggctggcgaaagtcagcaagcagccggtggcggtgattgtgacctccggc
acggcggtagcaaatctctatccggcactgattgaagctgggttaaccggagaaaaactg
atcctgttaaccgccgatcgcccgccggagctaattgactgcggcgcgaatcaggcaatt
cgccagccgggaatgttcgcctctcaccccacgcacagtatttcattgccgcgcccgacc
caggatatccccgcacgttggctggtttctaccatcgaccacgctctcggtacgcttcat
gtggggggagtccatatcaactgcccgtttgctgaaccgctgtatggcgaaatggacgat
accgggcttagctggcaacagcgtctgggtgactggtggcaggacgacaaaccgtggctg
cgtgaagcgcctcgtctggaaagtgaaaaacagcgcgactggttcttctggcgacaaaag
cgcggcgtggtggttgccgggcgcatgagtgcggaagagggcaaaaaagttgccctgtgg
gcgcaaactcttggctggccgctgattggcgatgtgctgtcacaaaccgggcagccgctg
ccgtgtgccgatctttggttaggcaatgccaaagcgaccagcgagctgcagcaggcgcaa
attgtggtgcaactgggaagcagcctgacggggaaacggctcctgcaatggcaggcaagc
tgtgaaccagaagagtactggattgttgatgacattgaagggcgacttgatccggcacac
catcgcggacgtcgcttaattgccaatattgccgactggctggagctgcatccggcagaa
aaacgccagccctggtgcgttgaaatcccgcgcctggcggaacaggcaatgcaggcggtt
attgcccgccgtgatgcgtttggcgaagcgcaactggcgcatcgcatctgcgactatctg
cctgaacaggggcaattgtttgttggtaacagcctggtggtacgtctgattgatgcgctt
tcgcaacttccggcaggttacccggtgtacagcaaccgaggggccagcggtatcgacgga
ctgctttcgaccgccgcaggcgttcagcgggcaagcggcaaaccgacgctggcgattgtg
ggcgatctctccgcactttacgatctcaacgcgctggcgttattgcgtcaggtttctgcg
ccgctggtattaattgtggtgaacaacaacggcgggcaaattttctcgctgttgccaacg
ccgcaaagcgagcgtgagcgtttctatctgatgccgcaaaacgtccattttgagcacgcc
gccgcgatgttcgagctgaaatatcatcgtccgcaaaactggcaggaacttgaaacggca
tttgccgacgcctggcgcacgccaaccaccacggtgattgaaatggtggttaacgacacc
gatggtgcgcaaacgctccagcaacttctggcgcaggtaagccatttatga
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