Etheostoma cragini (Arkansas darter): 117960222
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Entry
117960222 CDS
T07493
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ecra
Etheostoma cragini (Arkansas darter)
Pathway
ecra00270
Cysteine and methionine metabolism
ecra00480
Glutathione metabolism
ecra01100
Metabolic pathways
ecra01240
Biosynthesis of cofactors
ecra04216
Ferroptosis
Module
ecra_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ecra00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
117960222 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
117960222 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
117960222 (gclc)
Enzymes [BR:
ecra01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
117960222 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
117960222
NCBI-ProteinID:
XP_034753858
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Position
17:complement(13005488..13014114)
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AA seq
630 aa
AA seq
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MGLLSQGSPLNWEETRKYADHIRKHGIIQFLNIYNKVKERQRDVLKWGDEVEYMLVELDD
KDEKVRLVLNGGDVLETLQDQGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMGKRRREASSVLNHNETLCTITSFPRLGCPGFTKPEHRPTPVEKGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIFKDKCTPSPFVEEFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSINEARYLYDQLATFCPIVMALSAASPFYRGFVSDNDCRWEV
ISASVDDRTQEERGLKPLKNNKYRIFKSRYDSIDSYLSSCGEKYNDIDLTIDEEIYKQLL
DAGIDKLLAQHIAHLFIRDPLSVFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNSV
QEGMFYFRKDIFKGCNPVLDGTASAENGLETDGANEEYTLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAKHPQYKQDSVLTDKI
NYDLFRKCDKIAKGEEQCPELIGNPVNRFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtttactgtcacaggggtctccactgaactgggaagaaaccagaaagtatgccgac
cacatccgaaagcacggcatcattcagtttctcaacatctacaacaaggtgaaggaacgt
cagagagacgtgttgaaatggggcgatgaggttgagtacatgttggtggagttggatgac
aaggatgaaaaggtcaggctcgtcctgaacggcggagatgttctggaaactctccaagac
cagggtgaaaagataaaccccaaccaccccacactttggagaccagagtatggcagctac
atgattgaaggaaccccagggcagccgtacggcggcaccatgtcagagttcaacaccgtg
gagggcaacatggggaagagacgacgagaggcctcatcggtcctgaaccacaatgaaacc
ctctgcaccatcacctcgtttccaaggttaggttgcccaggtttcaccaaaccagagcac
cggccgacccctgttgaaaagggagtgtcgaagtcactgtttttcccagacgaagccatc
aacagacacccaagattcagcacccttaccagaaacatacgtcacagaagaggagagaaa
gtcgtgattaatgtgccaatcttcaaagacaagtgcaccccatctccgtttgtggaggag
tttcccgaggatgatggtgaagcagcgagggcggctctgcctgatcacatctacatggac
gccatgggctttggcatgggcaactgctgcctgcaggtgacattccaagcgtgtagcatt
aatgaggcaagatacctttacgaccaactggcaacattctgccccatagtgatggcgttg
agtgcggcctcacccttctacagaggctttgtgtccgataatgattgtcgctgggaagtt
atatctgcctcggtggacgacaggacgcaggaggaacgtgggctcaagcctttgaaaaac
aacaaataccggatcttcaagtcaagatacgattcaatcgacagctacctgtctagctgt
ggtgagaagtacaatgacattgatttgacgatagacgaggagatctacaagcagctgctc
gatgcaggaattgacaagctgctggcccagcacatagcacacctcttcataagagatcca
ctctccgtctttgaggagaaaatccacttggatgatgaaaacgagtcggatcacttcgag
aatcttcagtcgaccaactggcagacgatgaggttcaaacctccacctcccaactccgat
atcggctggagagttgagttccgccccatggaggtgcagctaactgactttgaaaacgct
gcgtatgtggtctttgtcgtcctgctcaccagagtgatcttgtcttacaaactggacttt
ctgatcccattgtcgaaggttgacgaaaacatgaaggttgctcagaagagaaactctgtc
caggagggcatgttttacttccgaaaggacatctttaaaggctgcaaccctgtccttgat
ggcacagcctccgctgagaacggcttggagactgatggtgctaacgaggaatacacgctt
atgagtatcgacacaatcatcaacggaaaggaaggagtatttcaagggcttataccaatc
cttaactgctatcttgaaaacatggaagtggatgtggacaccaggtgcaccattttgaat
tatctgaagctcatcaagaaacgtgcctcaggcgaactgatgaccatggccaagtggatg
agggaatttgttgccaagcacccgcagtataagcaggacagtgtgttaactgacaagatc
aactacgacctgttcaggaagtgtgacaagattgcgaaaggtgaagagcaatgcccggag
ctcattggaaacccagttaaccggtttaaatga
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