Escherichia coli O157 H7 Sakai (EHEC): ECs_0078 Help Entry ECs_0078          CDS       T00048                                  Symbol leuA Name (RefSeq) 2-isopropylmalate synthase   KO K01649   2-isopropylmalate synthase [EC:2.3.3.13] Organism ecs  Escherichia coli O157:H7 Sakai (EHEC) Pathway ecs00290   Valine, leucine and isoleucine biosynthesis ecs00620   Pyruvate metabolism ecs01100   Metabolic pathways ecs01110   Biosynthesis of secondary metabolites ecs01210   2-Oxocarboxylic acid metabolism ecs01230   Biosynthesis of amino acids Module ecs_M00432   Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate Brite KEGG Orthology (KO) [BR:ecs00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     ECs_0078 (leuA)   09105 Amino acid metabolism    00290 Valine, leucine and isoleucine biosynthesis     ECs_0078 (leuA) Enzymes [BR:ecs01000]  2. Transferases   2.3  Acyltransferases    2.3.3  Acyl groups converted into alkyl groups on transfer     2.3.3.13  2-isopropylmalate synthase      ECs_0078 (leuA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HMGL-like LeuA_dimer HCS_D2 IPMS_D2 Motif Other DBs NCBI-GeneID:  913513 NCBI-ProteinID:  NP_308105 UniProt:  Q8X9Z8 LinkDB All DBs Position complement(86566..88137) Genome browser AA seq 523 aa AA seqDB search MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF AGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF LKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKA EAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL ATDIVESSAKAMVHVLNNIWRATEVEKELQRKAQHNENNKETV NT seq 1572 nt NT seq  +upstreamnt  +downstreamnt atgagccagcaagtcattattttcgataccacattgcgcgacggtgaacaggcgttacag gcaagcttgagtgtgaaagaaaaactgcaaattgcgctggcccttgagcgtatgggtgtt gacgtgatggaagtcgggttccccgtctcttcgccgggtgattttgaatcagtgcaaacc atcgctcgccaggttaaaaacagccgtgtatgcgcgttagctcgctgcgtggagaaagat atcgacgtggcggccgaatccctgaaagtcgccgaagccttccgtattcatacctttatt gccacttcgccaatgcacatcgccaccaagctgcgcagcacgctggacgaggtgatcgaa cgcgctatctatatggtgaaacgcgcccgtaattacaccgatgatgttgaattttcttgc gaagatgccgggcgtacacccattgccgatctggcgcgagtggtcgaagcggcgattaat gccggtgccaccaccatcaacattccggacaccgtgggctacaccatgccgtttgagttc gccggaatcattagcggcctgtatgaacgcgtgcctaacatcgacaaagccattatttcc gtacatacccacgacgatttgggcctggcggtcggcaactcactggcggcggtacatgcc ggtgcacgccaggtggaaggtgcaatgaacgggatcggcgagcgtgccggtaactgttcc ctggaagaagtcatcatggcgattaaagttcgtaaggatattctcaacgtccacaccgcc attaatcaccaggagatatggcgcaccagccagttagttagccagatttgtaatatgccg atcccggcaaacaaagccattgttggcagcggcgcattcgcacactcctccggtatccac caggatggcgtgctgaaaaaccgcgaaaactacgaaatcatgacaccagaatctattggt ctgaaccaaatccagctgaatctgacctctcgttcggggcgtgcggcggtgaaacatcgc atggatgagatggggtataaagaaagtgaatataatttagacaatttgtacgacgccttc ctcaagctggcggacaaaaaaggtcaggtgtttgattacgatctggaggcgctggccttc atcggtaagcagcaagaagagccggagcatttccgtctggattacttcagcgtgcagtct ggctctaacgatatcgccaccgccgccgtcaaactggcctgcggcgaagaagtcaaagca gaagccgccaacggtaacggtccggtcgatgccgtctatcaggcgattaaccgcatcact gactataacgtcgaactggtgaaatacagcctgaccgccaaaggtcacggtaaagatgcg ctgggtcaggtggatattgtcgccaactacaacggtcgccgcttccacggcgtcggcctg gccaccgatattgtcgagtcctccgccaaagccatggtgcacgtacttaacaatatctgg cgtgccacagaagtcgaaaaagagttgcaacgcaaagctcaacacaacgaaaacaacaag gaaaccgtgtga

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