Escherichia coli O157 H7 Sakai (EHEC): ECs_0119
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Entry
ECs_0119 CDS
T00048
Symbol
aceF
Name
(RefSeq) pyruvate dehydrogenase
KO
K00627
pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:
2.3.1.12
]
Organism
ecs
Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00010
Glycolysis / Gluconeogenesis
ecs00020
Citrate cycle (TCA cycle)
ecs00620
Pyruvate metabolism
ecs00785
Lipoic acid metabolism
ecs01100
Metabolic pathways
ecs01110
Biosynthesis of secondary metabolites
ecs01120
Microbial metabolism in diverse environments
ecs01200
Carbon metabolism
ecs01210
2-Oxocarboxylic acid metabolism
Module
ecs_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ecs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
ECs_0119 (aceF)
00020 Citrate cycle (TCA cycle)
ECs_0119 (aceF)
00620 Pyruvate metabolism
ECs_0119 (aceF)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ECs_0119 (aceF)
Enzymes [BR:
ecs01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.12 dihydrolipoyllysine-residue acetyltransferase
ECs_0119 (aceF)
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Gene cluster
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Motif
Pfam:
2-oxoacid_dh
Biotin_lipoyl
E3_binding
Biotin_lipoyl_2
RnfC_N
GCV_H
NQRA_N
HlyD_D23
HlyD_3
Motif
Other DBs
NCBI-GeneID:
913659
NCBI-ProteinID:
NP_308146
UniProt:
Q8X966
Structure
PDB
PDBj
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All DBs
Position
130185..132077
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AA seq
630 aa
AA seq
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MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVS
VGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAVPEAAAAKDVNVPDIGSDEVEV
TEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEIKVNTGDKVSTGSLIMVFEVA
GEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDEVEVTEVMVKVGDKVAAEQSLIT
VEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAPAKQEAAAPAPA
AKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIRRLAREFGVNLAKVKGTGRKGRILRED
VQAYVKEAIKRAEAAPAATGGGIPGMLPWPKVDFSKFGEIEEVELGRIQKISGANLSRNW
VMIPHVTHFDKTDITELEAFRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSS
LSEDGQRLTLKKYINIGVAVDTPNGLVVPVFKDVNKKGIIELSRELMTISKKARDGKLTA
GEMQGGCFTISSIGGLGTTHFAPIVNAPEVAILGVSKSAMEPVWNGKEFVPRLMLPISLS
FDHRVIDGADGARFITIINNTLSDIRRLVM
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atggctatcgaaatcaaagtaccggacatcggggctgatgaagttgaaatcaccgagatc
ctggtcaaagtgggcgacaaagttgaagccgaacagtcgctgatcaccgtagaaggcgac
aaagcttctatggaagttccgtctccgcaggcgggtatcgttaaagagatcaaagtctct
gttggcgataaaactcagaccggcgcactgattatgattttcgattccgccgacggtgca
gcagacgctgcacctgctcaggcagaagagaagaaagaagcagctccggcagcagtcccc
gaggctgccgcggcaaaagacgttaacgttccggatatcggcagcgacgaagttgaagtg
accgaaatcctggtgaaagttggcgacaaagttgaagctgagcagtcgctgatcaccgta
gaaggcgataaagcttctatggaagttccggctccgtttgcaggcaccgtgaaagaaatc
aaagtgaacaccggcgacaaagtgtctaccggctcgctgattatggtcttcgaagtggcg
ggtgaagcaggcgcggcagctccggcggctaaacaggaagcggctccggcagcggcccct
gcaccagcggctggcgtgaaagaagttaacgttccggatatcggcggtgacgaagttgaa
gtgaccgaagtgatggtgaaagtgggcgacaaagttgccgctgaacagtcactgattacc
gtagaaggcgataaagcttctatggaagttccggctccgtttgcaggcgtcgtgaaggaa
ctgaaagtcaacgttggcgataaagtgaaaactggctcgctgattatgatcttcgaagtt
gaaggcgcagcgcctgcggcagctcctgcgaaacaggaagcagcagcgccggctccggca
gcaaaagctgaagccccggcagcagcaccggctgcgaaagcggaaggcaaatctgaattt
gctgaaaatgacgcttacgttcacgcgaccccgctgatccgccgtctggcacgcgagttt
ggcgttaaccttgcgaaagtgaagggcactggccgtaaaggtcgtatcctgcgcgaagac
gttcaggcttacgtgaaagaagctatcaaacgtgcagaagcagctccggcagcgactggc
ggtggtatccctggcatgctgccgtggccgaaggtggacttcagcaagtttggtgaaatc
gaagaagtggaactgggccgtatccagaaaatttctggtgcgaacctgagccgtaactgg
gtgatgatcccgcatgttactcacttcgacaaaaccgatatcaccgagctggaagcgttc
cgtaaacagcagaacgaagaagcggcgaaacgtaagctggatgtgaagatcaccccggtt
gtcttcatcatgaaagccgttgctgcagcgcttgagcagatgcctcgcttcaacagttcg
ctgtcggaagacggtcagcgtctgaccctgaagaaatacatcaacatcggtgtggcggtg
gataccccgaacggtctggttgttccggtattcaaagacgtcaacaagaaaggcatcatc
gaactgtctcgcgagctgatgactatttctaagaaagcgcgtgacggtaagctgactgcg
ggcgaaatgcagggcggttgcttcaccatctccagcatcggcggcctgggtactacccac
ttcgcgccgattgtgaacgcgccggaagtggctatcctcggcgtttccaagtccgcgatg
gagccggtgtggaatggtaaagagttcgtgccgcgtctgatgctgccgatttctctctcc
ttcgaccaccgcgtgatcgacggtgctgatggtgcccgtttcattaccatcattaacaac
acgctgtctgacattcgccgtctggtgatgtaa
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