Escherichia coli O157 H7 Sakai (EHEC): ECs_0122
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Entry
ECs_0122 CDS
T00048
Symbol
acnB
Name
(RefSeq) bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
ecs
Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00020
Citrate cycle (TCA cycle)
ecs00630
Glyoxylate and dicarboxylate metabolism
ecs00640
Propanoate metabolism
ecs00720
Other carbon fixation pathways
ecs01100
Metabolic pathways
ecs01110
Biosynthesis of secondary metabolites
ecs01120
Microbial metabolism in diverse environments
ecs01200
Carbon metabolism
ecs01210
2-Oxocarboxylic acid metabolism
ecs01230
Biosynthesis of amino acids
Module
ecs_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ecs_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
ecs_M00012
Glyoxylate cycle
ecs_M00982
Methylcitrate cycle
Brite
KEGG Orthology (KO) [BR:
ecs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ECs_0122 (acnB)
00630 Glyoxylate and dicarboxylate metabolism
ECs_0122 (acnB)
00640 Propanoate metabolism
ECs_0122 (acnB)
09102 Energy metabolism
00720 Other carbon fixation pathways
ECs_0122 (acnB)
Enzymes [BR:
ecs01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
ECs_0122 (acnB)
4.2.1.99 2-methylisocitrate dehydratase
ECs_0122 (acnB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
Motif
Other DBs
NCBI-GeneID:
913670
NCBI-ProteinID:
NP_308149
UniProt:
Q8X957
LinkDB
All DBs
Position
135988..138585
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AA seq
865 aa
AA seq
DB search
MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA
AYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDT
YRYLNFNQLSQYTEKADGVIFQTAV
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgctgaggggattgcgcccaaa
cccctggatgcaaaccaaatggccgcgcttgtagagctgctgaaaaacccgcccgcgggc
gaagaagaattcctgttagatctgttaaccaaccgtgttcctcctggcgtcgatgaagcc
gcctatgttaaagcaggcttcctggctgctgtcgccaaaggcgaagccaaatccccactg
ctgactccggaaaaagccatcgaactgctgggtactatgcagggtggttacaacattcat
ccgctgatcgatgcgctggatgatgccaaactggcaccgatcgctgccaaagcactttct
cacacactactgatgttcgataacttctatgacgtagaagagaaagcgaaagcaggcaac
gaatatgcgaagcaggttatgcagtcctgggctgatgccgaatggttcctgaatcgcccg
gcgctggctgaaaaactgaccgttaccgtcttcaaagtcactggcgaaaccaacaccgat
gacctttctccggcaccggatgcgtggtcacgcccggatatcccattgcacgcgctggcg
atgctgaaaaacgcccgtgaaggtattgagccagaccagccaggtgttgttggcccgatc
aaacagattgaagctctgcaacagaaaggtttcccgctggcgtacgtcggtgacgttgtg
ggtacgggttcatcgcgtaaatccgccacgaactccgttctgtggtttatgggcgatgat
attccacatgtgccgaacaaacgcggcggtggtttgtgcctcggcggtaaaattgcaccc
atcttctttaacacgatggaagatgcgggtgcgctgccaatcgaagtggatgtctctaac
ctgaacatgggcgacgtaattgacgtttacccgtacaaaggtgaagtacgtaaccacgaa
accggcgaactgctggcgaccttcgaactgaaaaccgacgtgctgattgatgaagtgcgt
gctggcggccgtattccgctgattatcggtcgtggcctgaccaccaaagcgcgtgaagca
cttggtctgccgcacagtgatgtgttccgtcaggcgaaagatgtcgctgagagcgatcgc
ggcttctcgctggcgcagaaaatggtaggccgtgcctgtggcgtgaaaggcattcgtccg
ggcgcgtactgtgaaccgaaaatgacttctgtaggctctcaggacaccacaggcccgatg
acccgtgatgaactgaaagacctggcgtgcctgggcttctcggctgacctggtgatgcag
tctttctgccacaccgcggcgtatccgaagccagttgacgtgaacacgcaccacacgctg
ccggacttcattatgaaccgtggcggtgtgtcgctgcgtccgggtgacggcgtaatccac
tcctggctgaaccgtatgctgctgccggataccgtcggtaccggtggtgactcccatacc
cgtttcccgatcggtatctctttcccggcgggttctggtctggtggcatttgcagccgca
acaggcgtaatgccgctggatatgccggaatccgttctggtgcgcttcaaaggcaaaatg
cagccgggcatcaccctgcgcgatctggtacacgccattccgctgtatgcgatcaaacaa
ggtctgctgaccgttgagaagaaaggcaagaaaaacatcttctctggccgcatcctagaa
attgaaggtctgccggatctgaaagttgagcaggcctttgagctgaccgatgcgtccgcc
gagcgttctgctgccggttgtaccatcaagctgaacaaagaaccaatcatcgaatacctg
aactccaacatcgtcctgctgaagtggatgatcgcggaaggttacggcgatcgtcgtacc
ctggaacgtcgtattcagggcatggaaaaatggctggcgaatcctgagctgctggaagcc
gatgcagatgcggaatacgcggcagtgatcgacatcgatctggcggatattaaagagcca
atcctctgtgctccgaacgacccggacgacgcacgtccgctgtctgcggtacagggcgag
aagatcgacgaagtgtttatcggttcttgcatgactaacatcggtcacttccgtgccgca
ggtaaactgctggatgcgcacaaaggtcagttgccgacccgcctgtgggtggcaccgcca
acccgtatggacgccgcacagttgaccgaagaaggctactacagcgtcttcggtaagagt
ggtgcgcgtatcgagatccctggctgttccctgtgtatgggtaaccaggcgcgtgtggcg
gacggtgcaacggtggtttccacctctacccgtaacttcccgaaccgtctgggtactggc
gcgaatgtcttcctggcttctgcggaactggctgctgttgcggcgctgattggcaaactg
ccgacgccggaagagtaccagacctacgtggcgcaggtagataaaacagccgttgatact
taccgttatctgaacttcaaccagctttctcagtacaccgagaaagccgatggggtgatt
ttccagactgcggtttaa
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