Escherichia coli O157 H7 Sakai (EHEC): ECs_1603
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Entry
ECs_1603 CDS
T00048
Symbol
purB
Name
(RefSeq) adenylosuccinate lyase
KO
K01756
adenylosuccinate lyase [EC:
4.3.2.2
]
Organism
ecs
Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00230
Purine metabolism
ecs00250
Alanine, aspartate and glutamate metabolism
ecs01100
Metabolic pathways
ecs01110
Biosynthesis of secondary metabolites
ecs01232
Nucleotide metabolism
ecs01240
Biosynthesis of cofactors
Module
ecs_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
ecs_M00049
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Brite
KEGG Orthology (KO) [BR:
ecs00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ECs_1603 (purB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
ECs_1603 (purB)
Enzymes [BR:
ecs01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.2 Amidine-lyases
4.3.2.2 adenylosuccinate lyase
ECs_1603 (purB)
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Gene cluster
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Motif
Pfam:
Lyase_1
ASL_C
Motif
Other DBs
NCBI-GeneID:
913288
NCBI-ProteinID:
NP_309630
UniProt:
Q8X737
Structure
PDB
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Position
complement(1612479..1613849)
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AA seq
456 aa
AA seq
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MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFA
ADAIGYLDAIVANFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFA
CTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTI
GKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQ
WNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPH
KVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQST
LKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMK
QFIDGLALPEEEKARLKAMTPANYIGRAITMVDELK
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atggaattatcctcactgaccgccgtttcccctgtcgatggacgctacggcgataaagtc
agcgcgctgcgcgggattttcagcgaatatggtttgctgaaattccgtgtacaagttgaa
gtacgttggctgcaaaaactggccgcgcacgcagcgatcaaggaagttcctgcttttgct
gccgacgcaatcggttaccttgatgcaattgtcgccaatttcagcgaagaagatgccgca
cgcatcaaaaccatcgagcgtactactaaccacgacgttaaagcggttgagtatttcctg
aaagaaaaagtggcggagatcccggaactgcacgcggtttctgaattcatccactttgcc
tgtacttcggaagatatcaataacctctcccacgcattaatgctgaaaaccgcgcgtgat
gaagtgatcctgccgtactggcgtcaactaattgatggcattaaagatctcgccgttcag
tatcgcgatatcccgctgctgtcccgtacccacggtcagccagccacgccgtcaaccatc
ggtaaagagatggcaaacgtcgcctaccgtatggagcgccagtaccgccagcttaaccag
gtggagatcctcggcaaaatcaacggcgcggtcggtaactataacgcccacatcgccgct
tacccggaagttgactggcatcagttcagcgaagagttcgtcacctcgctgggtattcaa
tggaacccgtacactacccagattgaaccgcacgactacattgccgaactgtttgattgc
gttgcgcgcttcaacaccattctgatcgactttgaccgtgacgtctggggttatatcgcc
cttaaccacttcaaacagaaaaccattgctggtgagattggttcttccaccatgccgcat
aaagttaacccgatcgacttcgaaaactccgaagggaatctgggcctttccaacgcggta
ttgcagcatctggcaagcaaactgccggtttcccgctggcagcgtgacctgaccgactcc
accgtgctgcgtaacctcggcgtgggtatcggttatgcgctgattgcgtatcaatccacc
ctgaaaggcgtgagcaaactggaagtgaaccgtgaccatctgctggatgagctggatcac
aactgggaagtgctggcagaaccaatccagacagttatgcgtcgctatggcatcgaaaaa
ccgtacgagaagctgaaagagctgactcgcggtaagcgcgttgacgccgaaggcatgaag
cagtttatcgacggtctggcgttgccagaagaagagaaagcccgcctgaaagcgatgacg
ccggctaactacattggtcgcgccatcaccatggttgatgagctgaaataa
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