KEGG   Escherichia coli O157 H7 Sakai (EHEC): ECs_1603
Entry
ECs_1603          CDS       T00048                                 
Symbol
purB
Name
(RefSeq) adenylosuccinate lyase
  KO
K01756  adenylosuccinate lyase [EC:4.3.2.2]
Organism
ecs  Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00230  Purine metabolism
ecs00250  Alanine, aspartate and glutamate metabolism
ecs01100  Metabolic pathways
ecs01110  Biosynthesis of secondary metabolites
ecs01232  Nucleotide metabolism
ecs01240  Biosynthesis of cofactors
Module
ecs_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
ecs_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Brite
KEGG Orthology (KO) [BR:ecs00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    ECs_1603 (purB)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    ECs_1603 (purB)
Enzymes [BR:ecs01000]
 4. Lyases
  4.3  Carbon-nitrogen lyases
   4.3.2  Amidine-lyases
    4.3.2.2  adenylosuccinate lyase
     ECs_1603 (purB)
SSDB
Motif
Pfam: Lyase_1 ASL_C
Other DBs
NCBI-GeneID: 913288
NCBI-ProteinID: NP_309630
UniProt: Q8X737
Structure
LinkDB
Position
complement(1612479..1613849)
AA seq 456 aa
MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFA
ADAIGYLDAIVANFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFA
CTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTI
GKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQ
WNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPH
KVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQST
LKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMK
QFIDGLALPEEEKARLKAMTPANYIGRAITMVDELK
NT seq 1371 nt   +upstreamnt  +downstreamnt
atggaattatcctcactgaccgccgtttcccctgtcgatggacgctacggcgataaagtc
agcgcgctgcgcgggattttcagcgaatatggtttgctgaaattccgtgtacaagttgaa
gtacgttggctgcaaaaactggccgcgcacgcagcgatcaaggaagttcctgcttttgct
gccgacgcaatcggttaccttgatgcaattgtcgccaatttcagcgaagaagatgccgca
cgcatcaaaaccatcgagcgtactactaaccacgacgttaaagcggttgagtatttcctg
aaagaaaaagtggcggagatcccggaactgcacgcggtttctgaattcatccactttgcc
tgtacttcggaagatatcaataacctctcccacgcattaatgctgaaaaccgcgcgtgat
gaagtgatcctgccgtactggcgtcaactaattgatggcattaaagatctcgccgttcag
tatcgcgatatcccgctgctgtcccgtacccacggtcagccagccacgccgtcaaccatc
ggtaaagagatggcaaacgtcgcctaccgtatggagcgccagtaccgccagcttaaccag
gtggagatcctcggcaaaatcaacggcgcggtcggtaactataacgcccacatcgccgct
tacccggaagttgactggcatcagttcagcgaagagttcgtcacctcgctgggtattcaa
tggaacccgtacactacccagattgaaccgcacgactacattgccgaactgtttgattgc
gttgcgcgcttcaacaccattctgatcgactttgaccgtgacgtctggggttatatcgcc
cttaaccacttcaaacagaaaaccattgctggtgagattggttcttccaccatgccgcat
aaagttaacccgatcgacttcgaaaactccgaagggaatctgggcctttccaacgcggta
ttgcagcatctggcaagcaaactgccggtttcccgctggcagcgtgacctgaccgactcc
accgtgctgcgtaacctcggcgtgggtatcggttatgcgctgattgcgtatcaatccacc
ctgaaaggcgtgagcaaactggaagtgaaccgtgaccatctgctggatgagctggatcac
aactgggaagtgctggcagaaccaatccagacagttatgcgtcgctatggcatcgaaaaa
ccgtacgagaagctgaaagagctgactcgcggtaagcgcgttgacgccgaaggcatgaag
cagtttatcgacggtctggcgttgccagaagaagagaaagcccgcctgaaagcgatgacg
ccggctaactacattggtcgcgccatcaccatggttgatgagctgaaataa

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