Escherichia coli O157 H7 Sakai (EHEC): ECs_2823
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Entry
ECs_2823 CDS
T00048
Symbol
hisB
Name
(RefSeq) histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase
KO
K01089
imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:
4.2.1.19
3.1.3.15
]
Organism
ecs
Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00340
Histidine metabolism
ecs01100
Metabolic pathways
ecs01110
Biosynthesis of secondary metabolites
ecs01230
Biosynthesis of amino acids
Module
ecs_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
ecs00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
ECs_2823 (hisB)
Enzymes [BR:
ecs01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.15 histidinol-phosphatase
ECs_2823 (hisB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.19 imidazoleglycerol-phosphate dehydratase
ECs_2823 (hisB)
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Gene cluster
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Motif
Pfam:
IGPD
Hydrolase_like
PNK3P
HAD_2
HAD
Hydrolase
Motif
Other DBs
NCBI-GeneID:
914091
NCBI-ProteinID:
NP_310850
UniProt:
Q9S5G5
Structure
PDB
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Position
2765669..2766736
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AA seq
355 aa
AA seq
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MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPQLLKLQKAGYKLVMITNQDGLG
TQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECDCRKPKVKLVERYLAEQAM
DRANSYVIGDRATDIQLAENMGINGLRYDRETLNWPMIGEQLTRRDRYAHVVRNTKETQI
DVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEINVKGDLYIDDHHTVEDTGLALG
EALKIALGDKRGICRFGFVLPMDECLARCALDISGRPHLEYKAEFTYQRVGDLSTEMIEH
FFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFGRTLRQAIRVEGDTLPSSKGVL
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
atgagtcagaagtatctttttatcgatcgcgatggaaccctgattagcgaaccgccgagt
gattttcaggtggatcgttttgacaaactcgcctttgaaccgggcgtgatcccgcaactg
ctgaagctgcaaaaagcgggctacaaactggtgatgatcactaatcaggatggtctggga
acacaaagtttcccgcaggcggatttcgatggcccgcacaacctgatgatgcagatattc
acctcgcaaggcgtacagtttgatgaagtgctgatttgtccgcacctgcccgccgatgag
tgcgactgccgtaaaccgaaagtaaaactggtggagcgttatctcgctgagcaagcgatg
gatcgcgccaacagttatgtgattggcgatcgcgcgaccgatattcaactcgctgaaaac
atgggcattaatggtttacgctacgaccgcgaaaccctgaactggccaatgattggcgag
caactcaccagacgtgaccgttacgctcacgtagtgcgtaataccaaagagacgcagatt
gacgttcaggtgtggctggatcgtgaaggtggcagcaagattaataccggcgttggcttc
tttgatcacatgctggatcagatcgccacccacggcggtttccgtatggaaatcaacgtc
aaaggcgacctctatatcgacgatcaccacaccgtcgaagataccggcctggcgctgggc
gaagcgttaaaaattgccctcggcgataaacgcggtatttgccgctttggttttgtgctg
ccgatggacgaatgccttgcccgctgcgcgctggatatctctggtcgcccgcacctggaa
tataaagccgagtttacctaccaacgcgtgggcgatctcagcaccgagatgatcgagcac
ttcttccgttcgctctcttacaccatgggcgtgacgctccacctgaaaaccaaaggtaaa
aacgatcatcaccgtgtagagagcctgttcaaagcctttggtcggaccctgcgccaggcc
atccgcgtggaaggcgataccctgccctcgtcgaaaggagtgctgtaa
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