Escherichia coli O157 H7 Sakai (EHEC): ECs_3152
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Entry
ECs_3152 CDS
T00048
Symbol
menD
Name
(RefSeq) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
ecs
Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00130
Ubiquinone and other terpenoid-quinone biosynthesis
ecs01100
Metabolic pathways
ecs01110
Biosynthesis of secondary metabolites
ecs01240
Biosynthesis of cofactors
Module
ecs_M00116
Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol
Brite
KEGG Orthology (KO) [BR:
ecs00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
ECs_3152 (menD)
Enzymes [BR:
ecs01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
ECs_3152 (menD)
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Motif
Pfam:
TPP_enzyme_M_2
TPP_enzyme_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
916860
NCBI-ProteinID:
NP_311179
UniProt:
Q8XDX8
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Position
complement(3108237..3109907)
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AA seq
556 aa
AA seq
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MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGH
LALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAI
RQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDD
TGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALW
AQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQAS
CEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAV
IACRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDG
LLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPT
PKSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETVLADAWRTPTTTVIEMVVNDT
DGAQTLQQLLAQVSHL
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgtcagtaagcgcatttaaccgacgctgggcggcggtcattctggaagcattaacgcgt
cacggcgtaagacacatctgcatcgcccctggctcgcgttctacaccgttaacgttagcg
gcggcggagaattccgcattcattcaccacacccatttcgatgagcgtggactggggcat
ctggcgctggggctggcgaaagtcagcaagcagccggtggcggtgattgtgacctccggc
acggcggtagcaaatctctatccggcactgattgaagctgggttaaccggagaaaaactg
atcctgttaaccgccgatcgcccgccggagctaattgactgcggcgcgaatcaggcgatt
cgtcagccgggaatgttcgcctctcaccccacgcacagtatttcactgccgcgcccgacc
caggatatccccgcacgttggctggtttctaccatcgaccatgctctcggtacgcttcat
gctggtggggtccatatcaactgcccgtttgctgaaccgctgtatggcgagatggacgac
actgggcttagctggcaacagcgtctgggtgactggtggcaggatgataagccgtggctg
cgtgaagcgcctcgtcttgagagcgaaaaacagcgcgactggttcttctggcggcaaaag
cgcggcgtggtggttgccgggcgcatgagtgcggaagagggcaaaaaagttgccctgtgg
gcgcaaactcttggctggccgctgattggcgacgtgctgtcgcaaaccggacagccgctg
ccgtgtgccgatctctggttaggcaatgccaaagcgaccagcgaactgcaacaggcgcaa
attgtggtgcaactgggaagcagcctgacgggcaaacggctcctgcaatggcaggcaagc
tgtgaacccgaagagtactggattgtggatgacatcgaagggcggcttgatccggcacac
catcgtggacgccgcttaattgccaatattgccgactggctggaactgcatccggcagaa
aaacgccagccctggtgcgttgaaatcccgcgcctggcggaacaggcaatgcaggcggtt
attgcctgtcgcgatgcgtttggcgaagcgcaactggcgcatcgcatcagcgactatctg
cctgaacaggggcaattgtttgtcggtaacagcctggtggtacgtctgattgatgcgctt
tcgcaacttccggcaggttacccggtgtacagcaaccgtggggccagcggtatcgacggg
ctgctctcgactgccgccggcgttcagcgggcaagcggcaaaccgacgctggcgattgtg
ggcgatctctccgcactttacgacctgaatgcgctggcgttattgcgccaggtttccgcg
ccgctggtattaattgtggtgaacaacaacggcgggcaaattttctcgctgctgccaacg
ccgaaaagcgagcgcgagcgtttctatctgatgccgcaaaacgtccattttgagcacgct
gccgcgatgtttgagctgaaatatcatcgtccgcaaaactggcaggaacttgaaacggta
cttgccgacgcctggcgtactccgaccaccacggtaattgaaatggtggttaacgacacc
gacggcgcgcaaacgctccagcagctgctggcgcaggtaagccatttatga
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