Escherichia coli O157 H7 Sakai (EHEC): ECs_3522
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Entry
ECs_3522 CDS
T00048
Symbol
gabD
Name
(RefSeq) succinate-semialdehyde dehydrogenase I
KO
K00135
succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:
1.2.1.16
1.2.1.79
1.2.1.20
]
Organism
ecs
Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00250
Alanine, aspartate and glutamate metabolism
ecs00310
Lysine degradation
ecs00350
Tyrosine metabolism
ecs00650
Butanoate metabolism
ecs00760
Nicotinate and nicotinamide metabolism
ecs01100
Metabolic pathways
ecs01120
Microbial metabolism in diverse environments
Module
ecs_M00027
GABA (gamma-Aminobutyrate) shunt
ecs_M00956
Lysine degradation, bacteria, L-lysine => succinate
Brite
KEGG Orthology (KO) [BR:
ecs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
ECs_3522 (gabD)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
ECs_3522 (gabD)
00310 Lysine degradation
ECs_3522 (gabD)
00350 Tyrosine metabolism
ECs_3522 (gabD)
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
ECs_3522 (gabD)
Enzymes [BR:
ecs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
ECs_3522 (gabD)
1.2.1.20 glutarate-semialdehyde dehydrogenase
ECs_3522 (gabD)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
ECs_3522 (gabD)
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-GeneID:
914762
NCBI-ProteinID:
NP_311549
UniProt:
Q8X950
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All DBs
Position
3513587..3515035
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AA seq
482 aa
AA seq
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MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRA
LPVWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA
EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK
PASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ
LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDG
VYDRFAEKLQQAVSKLHIGDGLDKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKA
HERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYA
RDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCI
GL
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atgaaactgaacgacagtaacttattccgccagcaggcgttgattaacggggaatggctg
gacgccaacaatggtgaagtcatcgacgtcaccaatccggcgaacggcgacaagctgggt
agcgtgccgaaaatgggcgctgatgaaactcgcgccgctatcgacgccgccaaccgcgcc
ctgcccgtctggcgtgcgctcaccgccaaagaacgcgccaacattctgcgcaactggttc
aatttgatgatggagcatcaggacgatttagcgcgcctgatgaccctcgaacagggtaaa
ccgctggctgaagcgaaaggcgaaatcagctacgccgcctcttttattgagtggtttgcc
gaagaaggcaaacgcatttatggcgacaccattcccggtcatcaggccgataagcgcctg
attgtgatcaagcagccgattggcgttacagcggccatcacgccgtggaactttccggcg
gcaatgattacccgcaaagccggtccggcgctggcggcaggctgcaccatggtgctgaag
cccgccagtcagacgccgttctctgcgctggcgctggcggagctggcgatccgcgcgggc
attccggctggcgtgtttaacgtggtcaccggttcggcgggcgcggtgggtaatgaactg
accagcaacccgctggtacgcaaactgtcgtttaccggctcgaccgaaattggccgccag
ttaatggaacagtgcgcgaaagacatcaaaaaagtgtcgctggagctgggcggcaacgcg
ccgtttatcgtctttgacgatgccgatctcgataaagccgtggaaggcgcactggcctcg
aaattccgcaacgccgggcaaacctgcgtctgcgccaaccgtttatacgtgcaggacggc
gtgtatgaccgctttgccgaaaaattgcagcaggcggtgagcaaactgcatatcggcgac
gggctggataaaggcgtcaccatcgggccgctgatcgatgaaaaagcggtagcaaaagtg
gaagagcatattgccgatgcgctggaaaaaggcgcgcgcgtagtttgcggcggtaaagca
catgaacgcggcggcaacttcttccagcccaccattctggtggacgtgccggccaacgcc
aaagtgtcgaaagaagagaccttcggccccctcgccccgctgttccgttttaaagatgaa
gccgatgtgatcgcgcaagccaatgacaccgagtttggccttgccgcctatttctatgcc
cgtgatttaagtcgcgtcttccgcgtgggcgaggcgctggagtacggcatcgtcggcatc
aataccgggattatttccaatgaagtggccccgttcggcggcattaaagcctcgggtctg
ggtcgtgaaggttcgaagtatggcatcgaagattacttagaaatcaaatatatgtgcatc
ggtctttaa
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