KEGG   Escherichia coli O157 H7 Sakai (EHEC): ECs_4870
Entry
ECs_4870          CDS       T00048                                 
Symbol
metF
Name
(RefSeq) 5,10-methylenetetrahydrofolate reductase
  KO
K00297  methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
Organism
ecs  Escherichia coli O157:H7 Sakai (EHEC)
Pathway
ecs00670  One carbon pool by folate
ecs00720  Other carbon fixation pathways
ecs01100  Metabolic pathways
ecs01120  Microbial metabolism in diverse environments
ecs01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:ecs00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    ECs_4870 (metF)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    ECs_4870 (metF)
Enzymes [BR:ecs01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     ECs_4870 (metF)
SSDB
Motif
Pfam: MTHFR
Other DBs
NCBI-GeneID: 915018
NCBI-ProteinID: NP_312897
UniProt: Q8X766
LinkDB
Position
4939625..4940515
AA seq 296 aa
MNFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTY
GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGD
LPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA
ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
NT seq 891 nt   +upstreamnt  +downstreamnt
atgaacttttttcacgccagccagcgggatgccctgaatcagagcctggcagaagtccag
gggcagattaacgtttcgttcgagtttttcccgccgcgtaccagtgaaatggagcagacc
ctgtggaactccatcgatcgccttagcagcctgaaaccgaagtttgtatcggtgacctat
ggcgcgaactccggcgagcgcgaccgtacgcacagcattattaaaggcattaaagatcgc
actggtctggaagcggcaccgcatcttacttgcattgatgcgacgcccgacgagttgcgc
accattgcacgcgactactggaataacggtattcgtcatatcgtggcgctgcgtggcgat
ctgccgccgggaagtggtaagccagaaatgtatgcttctgacctggtgacgctattaaaa
gaagtggcagatttcgatatctccgtggcggcgtatccggaagttcacccggaagcaaaa
agcgcccaggcggatttgcttaacctgaaacgcaaagtcgatgcaggagccaaccgcgcg
attactcagttcttctttgatgtcgaaagctacctgcgttttcgtgaccgctgtgtgtcg
gcgggcattgatgtggaaatcattccgggcatattgccggtatctaactttaaacaggcg
aagaaatttgccgacatgaccaacgtgcgtattccggcgtggatggcgcaaatgtttgac
gggctggatgacgatgccgaaacccgcaagctggtgggcgcgaatattgccatggatatg
gtgaagattttaagccgtgaaggagtgaaagatttccacttctatacgcttaaccgcgct
gaaatgagttacgcgatttgccatacgctgggggttcgacctggtttataa

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