Escherichia coli O7 K1 IAI39 (ExPEC): ECIAI39_0089
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Entry
ECIAI39_0089 CDS
T00829
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ect
Escherichia coli O7:K1 IAI39 (ExPEC)
Pathway
ect00300
Lysine biosynthesis
ect00550
Peptidoglycan biosynthesis
ect01100
Metabolic pathways
ect01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ect00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ECIAI39_0089 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECIAI39_0089 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ECIAI39_0089 (murF)
Enzymes [BR:
ect01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ECIAI39_0089 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
CAR16230
UniProt:
A0A0H3ME10
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Position
104872..106230
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILNQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIKLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDCVLSVGKQSHAISTASGVGEHFTDKTALIARLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgatattctcaacggtgaactgcaaggtgca
gatattacccttgatgctgtaaccactgacacgcgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgtttcgatgctcatgattttgccgaccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggatatcgatctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacaggttcctccggcaaaacatccgttaaagagatgacggcggca
attttaaaccagtgcggcaacacactttatacggcaggcaatctcaataacgacatcggt
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggtgaaattgcctggactgtgagtctgactcgcccggaagcggcgctg
gtcaacaacctggcagcggcacatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatatttagcggcctgccggaaaacggtatcgccatcatgaacgctgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cccaatgccgccaacagcgatttcaccgccaccaatatccatgtgacttcgcacggtacg
gaatttaccctgcaaaccccaacaggtagcgtcgatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtctgttccccata
aaactggcagaaaaccagttgctgctcgacgactcctacaacgccaatgtcggttcaatg
accgccgctgttcaggttctggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaagcggcaaaa
gctgctggtattgactgcgtgttaagtgtgggtaaacaaagccatgctatcagcactgcc
agcggtgttggcgaacattttaccgataaaactgcgcttatcgcgcgtcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgccgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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