KEGG   Escherichia coli O7 K1 IAI39 (ExPEC): ECIAI39_2865
Entry
ECIAI39_2865      CDS       T00829                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase 2, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
ect  Escherichia coli O7:K1 IAI39 (ExPEC)
Pathway
ect00230  Purine metabolism
ect00240  Pyrimidine metabolism
ect01100  Metabolic pathways
ect01232  Nucleotide metabolism
Module
ect_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
ect_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ect00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    ECIAI39_2865 (nrdE)
   00240 Pyrimidine metabolism
    ECIAI39_2865 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ect03400]
    ECIAI39_2865 (nrdE)
Enzymes [BR:ect01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     ECIAI39_2865 (nrdE)
DNA repair and recombination proteins [BR:ect03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    ECIAI39_2865 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN LOB
Other DBs
NCBI-ProteinID: CAR18987
UniProt: A0A0H3MJM1
LinkDB
Position
2970753..2972897
AA seq 714 aa
MATTTAERLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFMTTHVRPNSVAFSSQQ
QRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHASGFRFQTFLGAWKFYTSYTLKTFDGK
RYLEDFADRVTMVALTLAQGDETLATQLTDEMLSGRFQPATPTFLNCGKQQRGELVSCFL
LRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLED
AFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLA
KENAQMALFSPYDVERVYGKPFADVAISEHYDELVADERIRKKYLNARDFFQRLAEIQFE
SGYPYIMYEDTVNRANPIAGRINMSNLCSEILQVNSASEYDENLDYARTGHDISCNLGSL
NIAHTMDSPDFARTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAR
EGIAYGSPEALDFTNLYFYTITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQS
NWQPKTAKVGELFARSGITLPTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATS
SIHPIVAKVEIRKEGKTGRVYYPAPFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQG
LSLTLFFHDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL
NT seq 2145 nt   +upstreamnt  +downstreamnt
ttggcaacgacaaccgcagaacgcctgacgcaggaaacgatggattatcacgctctgaat
gcgatgcttaacctttacgatagcgcaggtcgcattcagttcgataaagatcgccaggca
gtagacgcctttatgacgacgcatgtgcgtccgaacagtgtggccttcagtagccagcag
cagcgcctgaactggctggttaacgaaggttactatgatgaaagtgtccttaatcgctac
tctcgcgattttgtcattacgctgtttgcccacgcgcacgccagcggttttcgtttccag
acattcctcggagcatggaagttttacaccagctatacgttgaagacattcgacggtaag
cgttatctggaagattttgccgatcgcgtcacgatggtggcgctgacgctggcacaaggc
gatgaaacactggcgacgcagctcactgatgagatgctgtcaggacgctttcagccagcc
acgccaacattcctcaactgcggtaagcagcagcgcggcgaactggtttcctgttttctg
ctgcgtattgaagacaatatggagtcgattggccgggcagtaaattccgcactacaactg
tcgaaacgcggcggcggcgtagcatttttgctgtcgaatctgcgggaagcgggcgcgcca
attaaacgtattgaaaatcaatcttctggcgtgattccggtgatgaaaatgctggaagac
gcattttcctatgccaaccaactcggcgcgcgtcagggggctggggcagtctatttacat
gctcatcatcccgatattctgcgttttctcgatacaaaacgggaaaatgccgacgaaaaa
atccgcattaaaacactgtcgctgggcgtggtgatcccggatatcactttccatctggcg
aaagagaatgcgcagatggcgctgttttcgccctatgacgttgagcgggtttatggcaag
ccgtttgccgatgtcgccatcagtgaacactatgacgaactggttgccgatgaacgcatt
cgcaaaaaatacctcaacgcccgtgatttcttccagcgactggcagagatccagtttgag
tctggctatccgtacatcatgtatgaagacacggttaaccgtgctaaccctatcgccggg
cgcataaatatgagcaatctctgctcagaaattttgcaggttaacagcgcctcagaatat
gacgagaatctcgactatgctcgtacaggccatgatatttcctgcaatctagggtcgttg
aatattgcccacaccatggattcccccgactttgcccgcacggtagagactgccgtacgc
ggtttaacggcggtgtcagatatgagtcatatccgcagcgtgccgtccatcgaagccgga
aatgccgcctcacacgccatcggtctggggcagatgaatttacacggttatctggcgcga
gaaggcatcgcttatggttcgccggaagcactggatttcaccaatctctatttctatacc
atcacctggcacgcactgcgtacctcgatgttgctggcgcgcgaacgcggtgaaaccttc
gccgggttcaaacagtcacgctatgccagtggtgaatatttcagccaatatctgcaaagt
aactggcagccgaaaacggcgaaagttggcgaactgtttgcccgtagtggtattacgtta
cctacccgtgagatgtgggcgcagctgcgcgacgacgtgatgcgctatggcatatacaac
cagaatctccaggcggtgccgccaaccggttctatctcttatatcaaccatgccacgtcg
agtattcatccgattgtggcgaaagtagagatacgcaaagagggcaaaacaggacgcgtt
tactaccctgccccgtttatgactaacgaaaatctggcgctgtatcaggacgcttacgaa
atcggcgcagaaaagatcatcgacacctacgcggaagcgactcgccatgtcgatcagggg
ctgtcgctgacgctgtttttccacgataccgccaccactcgcgatatcaacaaagcgcag
atttacgcctggcgcaaaggtatcaaaacactctattacattcgcctgcgtcagatggcg
ctggaaggcactgaaattgaaggctgcgtctcctgtgcactttaa

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