KEGG   Escherichia coli APEC O1 (APEC): APECO1_3088
Entry
APECO1_3088       CDS       T00425                                 
Symbol
cysG
Name
(GenBank) multifunctional protein; Uroporphyrin-III C-methyltransferase; Ferrochelatase; Precorrin-2 oxidase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
ecv  Escherichia coli APEC O1 (APEC)
Pathway
ecv00860  Porphyrin metabolism
ecv01100  Metabolic pathways
ecv01110  Biosynthesis of secondary metabolites
ecv01120  Microbial metabolism in diverse environments
ecv01240  Biosynthesis of cofactors
Module
ecv_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:ecv00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    APECO1_3088 (cysG)
Enzymes [BR:ecv01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     APECO1_3088 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     APECO1_3088 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     APECO1_3088 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Col-Pyo_DNase Radical_SAM
Other DBs
NCBI-ProteinID: ABJ02842
UniProt: A1AGQ2
LinkDB
Position
3788609..3789982
AA seq 457 aa
MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTL
VEGPFDESLLDTCWLAIAATDDDALNQRVSEAAESRRIFCNVVDAPKAASFIMPSIIDRS
PLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWE
KLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQ
QADVVVYDRLVSDDIMNLIRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLK
GGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHL
KTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEYGMPGEMPVAIVENGTAVTQRVID
GTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
NT seq 1374 nt   +upstreamnt  +downstreamnt
gtggatcatttgcctatattttgccaattacgcgatcgcgactgtctgattgtcggcggt
ggtgatgtcgcggaacgcaaagcaaggttgctgttagacgcaggcgctcgcttaacggtg
aatgcattagcgtttattccacagttcaccgcatgggcagatgcaggcatgttaaccctc
gtcgaagggccatttgatgaaagccttctcgacacctgctggctggcgattgcagcgaca
gatgatgacgcgcttaaccagcgcgtcagcgaagccgctgaatctcgtcgtatcttctgt
aacgtggtcgatgcgccgaaagccgccagctttattatgccgtcgattattgaccgctca
ccgctcatggtagcggtatcctctggcggtacttctccggttctggcgcgcctgttgcgc
gaaaaactcgaatcactgctgccgttacatctgggccaggtagcgaaatacgccgggcaa
ttacgcgggcgagtaaaacagcagttcgccacgatgggtgagcgtcgccgtttctgggag
aaattgttcgttaacgaccgcctggcgcagtcgctggccaacaacgatcagaaagccatt
actgaaaccaccgaacagttaatcaatgaaccgctcgaccatcgcggtgaagtggtgctg
gttggtgcaggtccgggcgatgccgggctgctgacactgaaaggtctgcaacaaattcag
caggcagatgtggtggtctacgaccgtctggtttctgacgatattatgaatctgatacgc
cgcgatgctgatcgcgttttcgtcggcaaacgcgcgggataccactgcgtaccgcaggaa
gagattaaccagatcttgctgcgggaagcgcaaaaaggtaaacgcgtggtgcgtctgaaa
ggcggcgatccgtttattttcgggcgtggcggagaagagctggaaacactgtgcaacgcg
ggtattccgttctcggtggttccgggtattaccgcagcttctggttgctctgcctattcg
ggtattccgctcacgcatcgcgattatgcccagagcgtacgcttaattaccggacactta
aaaaccggtggcgagctggactgggaaaacctggcggcagaaaaacagacgctggtgttc
tatatggggctgaatcaggctgcaactattcagcaaaagctgattgaatacggtatgcct
ggtgaaatgccggtggcaattgtcgaaaacggaacggcagtcacgcagcgcgtgattgac
ggtacgctcacgcagctgggcgaactggcgcagcaaatgaacagtccatcgctaattatt
attggtcgggttgttggcctgcgcgataaattgaactggttctctaaccattaa

DBGET integrated database retrieval system