Escherichia coli O139 H28 E24377A (ETEC): EcE24377A_2560
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Entry
EcE24377A_2560 CDS
T00590
Symbol
menD
Name
(GenBank) 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
ecw
Escherichia coli O139:H28 E24377A (ETEC)
Pathway
ecw00130
Ubiquinone and other terpenoid-quinone biosynthesis
ecw01100
Metabolic pathways
ecw01110
Biosynthesis of secondary metabolites
ecw01240
Biosynthesis of cofactors
Module
ecw_M00116
Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol
Brite
KEGG Orthology (KO) [BR:
ecw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
EcE24377A_2560 (menD)
Enzymes [BR:
ecw01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
EcE24377A_2560 (menD)
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Motif
Pfam:
TPP_enzyme_M_2
TPP_enzyme_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
ABV20047
UniProt:
A7ZP83
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Position
complement(2552446..2554116)
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AA seq
556 aa
AA seq
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MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGH
LALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAI
RQPGMFASHPTHSISLPRPTQDIPACWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDD
TGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALW
AQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQAS
CEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAV
IARRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDG
LLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPT
PQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDT
DGAQTLQQLLAQVSHL
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgtcagtaagcgcatttaaccgacgctgggcggcggtcattctggaagcattaacgcgt
cacggcgtcagacacatctgtatcgccccaggctcgcgttctacaccgttaacgttagcg
gcggcggagaattccgcattcattcaccacacccatttcgatgagcgtggactggggcat
ctggcgctggggctggcgaaagtcagcaagcagccggtggcggtgattgtgacctccggc
acggcggtggcaaatctctatccggcactgattgaagccgggttaaccggagaaaaactg
attctcttaaccgccgatcgcccgccggagctaattgactgcggcgcgaatcaggcaatt
cgccagccgggaatgttcgcctctcaccccacgcacagtatttcattgccgcgcccgacc
caggatatccccgcatgttggctggtttctaccatcgaccacgctctcggtacgcttcat
gcggggggagtccatatcaactgcccgtttgctgaaccgctgtatggcgaaatggacgat
accgggcttagctggcaacagcgtctgggtgactggtggcaggacgacaaaccgtggctg
cgtgaagcgcctcgtctggaaagtgaaaaacagcgcgactggttcttctggcgacaaaag
cgcggcgtggtggttgccgggcgcatgagtgcggaagagggcaaaaaagttgccctgtgg
gcgcaaactcttggctggccgctgattggcgatgtgctgtcacaaaccgggcagccgctg
ccgtgtgccgatctttggttaggcaatgccaaagcgaccagcgagctgcagcaggcgcaa
attgtggtgcaactgggaagcagcctgacggggaaacggctcctgcaatggcaggcaagc
tgtgaacccgaagagtactggattgttgatgacattgaagggcgacttgatccggcacac
catcgcggacgtcgcttaattgccaatattgccgactggctggagctgcatccggcagaa
aaacgccagccctggtgcgttgaaatcccgcgcctggcggaacaggcaatgcaggcggtt
attgcccgccgtgatgcgtttggcgaagcgcaactggcgcatcgcatcagcgactatctg
cctgaacaggggcaattgtttgttggtaacagcctggtggtacgtctgattgatgcgctt
tcgcaacttccggcaggttacccggtgtacagcaaccgaggggccagcggtatcgacgga
ctgctttcgaccgccgcaggcgttcagcgggcaagcggcaaaccgacgctggcgattgtg
ggcgatctctccgcactttacgatctcaacgcgctggcgttattgcgtcaggtttctgcg
ccgctggtattaattgtggtgaacaacaacggcgggcaaattttctcgctgttgccaacg
ccgcaaagcgagcgtgagcgtttctatctgatgccgcaaaacgtccattttgagcacgcc
gccgcgatgttcgagctgaaatatcatcgtccgcaaaactggcaggaacttgaaacggca
tttgccgacgcctggcgcacgccaaccaccacggtgattgaaatggtggttaacgacacc
gatggtgcgcaaacgctccagcaacttctggcgcaggtaagccatttatga
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