Escherichia coli O139 H28 E24377A (ETEC): EcE24377A_2609
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Entry
EcE24377A_2609 CDS
T00590
Symbol
folC
Name
(GenBank) tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
ecw
Escherichia coli O139:H28 E24377A (ETEC)
Pathway
ecw00790
Folate biosynthesis
ecw01100
Metabolic pathways
ecw01240
Biosynthesis of cofactors
Module
ecw_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
ecw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EcE24377A_2609 (folC)
Enzymes [BR:
ecw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EcE24377A_2609 (folC)
6.3.2.17 tetrahydrofolate synthase
EcE24377A_2609 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ABV17010
UniProt:
A7ZPD0
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Position
complement(2602116..2603384)
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AA seq
422 aa
AA seq
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MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGVLKPAPFVFTVAGTNGK
GTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPESAHIASFAEIESARGDIS
LTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWTFSD
AHGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVI
FDVAHNPHAAEYLTGRMKALPKNGHVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGP
RGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLVCGSFHTVAHVMEVIDARRSG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgattatcaaacgcactcctcaagccgcgtcgcctctggcttcgtggctttcttatctg
gaaaacctgcacagtaaaactatcgatctcggccttgagcgcgtgagccaggtcgcggcg
cgtcttggcgttctgaaaccagcgccatttgtgtttaccgttgcgggtacgaatggcaaa
ggcaccacctgccgtacgctggagtcgattctgatggcggcagggtacaaagtgggcgtc
tacagttcaccgcatctggtgcgttataccgagcgcgtacgtgtgcagggccaggaattg
ccggaatcggcccacatcgcctcttttgcggagattgaatcggcacgcggtgatatttcc
ctgacctatttcgagtacggtacgctgtcggcgttgtggctgttcaagcaggcacaactt
gacgtggtgattctggaagtagggctgggcggtcgtctggacgcaaccaatattgtcgac
gccgatgtcgcggtagtaaccagcattgcgctggatcataccgactggctggggccagat
cgcgaaagtattggtcgcgagaaagcaggcatctttcgcagcgaaaaaccggcaattgtc
ggtgagccggaaatgccttctaccattgctgatgtggcgcaggaaaaaggtgcactgtta
caacgtcggggcgttgagtggaactattccgtcaccgatcatgactggacgtttagcgat
gctcacggcacgctggaaaatttgccgttgccgcttgtcccgcaaccgaatgccgcaacg
gcgctggcggcactgcgtgccagcgggctggaggtcagtgaaaatgccattcgcgacggg
attgccagcgcaattttgccgggacgtttccagattgtgagcgagtcgccacgcgttatt
tttgatgtcgcgcataatccacatgcggcggaatatctcaccgggcgtatgaaagcctta
ccgaaaaacgggcacgtgctggcggttatcggtatgctacatgataaagatattgccgga
actctggcctggttgaaaagcgtggttgatgactggtattgtgcgccactggaagggccg
cgcggtgccacggcagaacaactgcttgagcatttgggtaacggcaaatcatttgatagc
gttgcgcaggcatgggatgccgcaatggcggacgctaaagcggaagacaccgtgctggtg
tgtggttctttccacacggtcgcacatgtcatggaagtgattgacgcgaggagaagcggt
ggcaagtaa
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