| Entry |
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| Symbol |
thrA
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| Name |
(GenBank) aspartokinase/homoserine dehydrogenase I
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| KO |
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| Organism |
ecx Escherichia coli O9 HS (commensal)
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| Pathway |
| ecx00260 | Glycine, serine and threonine metabolism |
| ecx00270 | Cysteine and methionine metabolism |
| ecx01110 | Biosynthesis of secondary metabolites |
| ecx01120 | Microbial metabolism in diverse environments |
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| Module |
| ecx_M00016 | Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine |
| ecx_M00017 | Methionine biosynthesis, aspartate => homoserine => methionine |
| ecx_M00018 | Threonine biosynthesis, aspartate => homoserine => threonine |
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| Brite |
KEGG Orthology (KO) [BR:ecx00001]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EcHS_A0003 (thrA)
00270 Cysteine and methionine metabolism
EcHS_A0003 (thrA)
00300 Lysine biosynthesis
EcHS_A0003 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
EcHS_A0003 (thrA)
Enzymes [BR:ecx01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
EcHS_A0003 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
EcHS_A0003 (thrA)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
336..2798
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| AA seq |
820 aa
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDA
LPNISDAERIFAELLTGLTAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQSSSEYSISF
CVPQSDCVRAERAMQEEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLNLENWQEELAQAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHLLRHAAEKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMA
NLSQLDDLFAARVAKARDEGKVLRYVGNIDEDGACRVKIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV |
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| NT seq |
2463 nt +upstreamnt +downstreamnt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgggtt
gccgatattctggaaagcaatgccaggcaggggcaggtggccaccgtcctctctgccccc
gccaaaatcaccaaccacctggtggcgatgattgaaaaaaccattagcggccaggatgct
ttacccaatatcagcgatgccgaacgtatttttgccgaacttctgacgggactcaccgcc
gcccagccgggattcccgctggcgcaactgaaaactttcgtcgaccaggaatttgcccaa
ataaaacatgtcctgcatggcattagtttgttggggcagtgcccggatagcatcaacgct
gcgctgatttgccgtggcgagaaaatgtcgatcgccattatggccggcgtgttagaagcg
cgtggtcacaacgttaccgttatcgatccggtcgaaaaactactggcagtggggcattac
ctcgaatctaccgtcgatattgctgagtccacccgccgtattgcggcaagtcgtattccg
gctgatcacatggtgctgatggcaggcttcaccgccggtaatgaaaaaggcgaactggtg
gtacttggacgcaacggttccgactactccgcggcggtgctggctgcctgtttacgcgcc
gattgttgcgagatttggacggacgttgacggggtctatacctgcgacccgcgtcaggtg
cccgatgcgaggttgttgaagtcgatgtcctaccaggaagcgatggagctttcctacttc
ggcgctaaagttcttcacccccgcaccattacccccatcgcccagttccagatcccttgc
ctgattaaaaataccggaaatcctcaagcaccaggtacgctcattggtgccagccgtgat
gaagacgaattaccggtcaagggcatttccaatctgaataacatggcaatgttcagcgtt
tctggtccgggaatgaaagggatggtcggcatggcggcgcgcgtctttgcagcgatgtca
cgcgcccgtatttccgtggtgctgattacgcaatcatcttccgaatacagtatcagtttc
tgcgttccgcaaagcgactgtgtgcgagctgaacgggcaatgcaggaagagttctacctg
gaactgaaagaaggcttactggagccgctggcggtgacggaacggctggccattatctcg
gtggtaggtgatggtatgcgcaccttgcgtgggatctcggcgaaattctttgccgcgctg
gcccgcgccaatatcaacattgtcgccattgctcagggatcttctgaacgctcaatctct
gtcgtggtaaataacgatgatgcgaccactggcgtgcgcgttactcatcagatgctgttc
aataccgatcaggttatcgaagtgtttgtgattggcgtcggtggcgttggcggtgcgctg
ctggagcaactgaagcgtcaacaaagctggctgaagaataaacatatcgacttacgtgtc
tgcggtgttgccaactcgaaggcactgctcaccaatgtgcatggcctaaatctggaaaac
tggcaggaagaactggcgcaagccaaagagccgtttaatctcgggcgcttaattcgcctc
gtgaaagaatatcatctgctgaacccggtcattgttgactgcacctccagccaggcagtg
gcggatcaatatgccgacttcttgcgcgaaggtttccacgttgtcacgccgaacaaaaag
gccaacacctcgtcgatggattactaccatctgttgcgtcatgcggcggaaaaatcgcgg
cgtaaattcctctatgacaccaacgttggggctggattaccggttattgagaacctgcaa
aatctgctcaatgctggtgatgaattgatgaagttctccggcattctttcaggttcgctt
tcttatatcttcggcaagttagacgaaggcatgagtttctccgaggcgactactctggcg
cgggaaatgggttataccgaaccggatccgcgagatgatctttctggtatggatgtagcg
cgtaagctattgattctcgctcgtgaaacgggacgtgaactggagctggcggatattgaa
attgaacctgtgctgcccgcagagtttaacgctgagggtgatgttgccgcttttatggcg
aatctgtcacagctcgacgatctctttgccgcgcgcgtggcgaaggcccgtgatgaagga
aaagttttgcgctatgttggcaatattgatgaagatggtgcctgccgcgtgaagattgcc
gaagtggatggtaatgatccgctgttcaaagtgaaaaatggcgaaaacgccctggccttt
tatagccactattatcagccgctgccgttggtgctgcgcggatatggtgcgggcaatgac
gttacagctgccggtgtctttgccgatctgctacgtaccctctcatggaagttaggagtc
tga |
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