Escherichia coli O9 HS (commensal): EcHS_A0077
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Entry
EcHS_A0077 CDS
T00591
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ecx
Escherichia coli O9 HS (commensal)
Pathway
ecx00290
Valine, leucine and isoleucine biosynthesis
ecx00660
C5-Branched dibasic acid metabolism
ecx01100
Metabolic pathways
ecx01110
Biosynthesis of secondary metabolites
ecx01210
2-Oxocarboxylic acid metabolism
ecx01230
Biosynthesis of amino acids
Module
ecx_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ecx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
EcHS_A0077 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EcHS_A0077 (leuC)
Enzymes [BR:
ecx01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
EcHS_A0077 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
EcHS_A0077 (leuC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ABV04477
UniProt:
A7ZW23
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All DBs
Position
complement(81219..82619)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAIAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaaaacgttatacgaaaaattgttcgacgctcacgttgtgtacgaagccgaaaac
gaaaccccactgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgctacc
atggatcacaacgtctctacccagaccaaagacattaatgcctgcggtgaaatggcgcgt
atccagatgcaggaactgatcaaaaactgcaaagaatttggcgtcgaactgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggcgtcaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgcgcaaaaaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattatcggtaaaaccggtagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaatccgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcaatcgaaatgggcgcaaaagccggtctggttgcaccggacgaaaccaccttt
aactatgtcaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccattgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactctgcaa
gcagaagaaatttcaccgcaggtcacctggggcaccaatcccggccaggtgatttccgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgtgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggtattccgctgaccgaagtggctatcgac
aaagtgtttatcggttcctgtaccaactcgcgcattgaagatttacgcgcggcagcggag
atcgccaaagggcgaaaagtcgcgccaggcgtgcaggcactggtggttcccggctctggc
ccggtaaaagcccaggcggaagcggaaggtctggataaaatctttattgaagccggtttt
gaatggcgcttacctggctgctcaatgtgtctggcgatgaacaacgaccggctgaatccg
ggcgaacgttgtgcctccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgccgcggctgtgaccggccatttcgcc
gacattcgcaacattaaataa
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