KEGG   Escherichia coli O9 HS (commensal): EcHS_A0603
Entry
EcHS_A0603        CDS       T00591                                 
Symbol
folD
Name
(GenBank) methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
ecx  Escherichia coli O9 HS (commensal)
Pathway
ecx00670  One carbon pool by folate
ecx01100  Metabolic pathways
ecx01120  Microbial metabolism in diverse environments
ecx01200  Carbon metabolism
ecx01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:ecx00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    EcHS_A0603 (folD)
Enzymes [BR:ecx01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     EcHS_A0603 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     EcHS_A0603 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-ProteinID: ABV04987
UniProt: A7ZXI3
LinkDB
Position
complement(616396..617262)
AA seq 288 aa
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEE
VGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDV
DGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELL
LAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKV
VGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
NT seq 867 nt   +upstreamnt  +downstreamnt
atggcagcaaagattattgacggtaaaacgattgcgcagcaggtgcgctctgaagttgct
caaaaagttcaggcgcgtattgcagccggactgcgggcaccaggactggccgttgtgctg
gtgggtagtaaccctgcatcgcaaatttatgtcgcaagcaaacgcaaggcttgtgaagaa
gtcgggttcgtctcccgctcttatgacctcccggaaaccaccagcgaagcggagctgttg
gagcttatcgatgcgctgaatgccgacaacaccatcgatggcattctggttcaactgccg
ttaccggcgggtattgataacgtcaaagtgctggaacgtattcatccggacaaagacgtg
gacggtttccatccttataacgtcggtcgtctgtgccagcgcgcgccgcgtctgcgtccc
tgcaccccgcgcggtatcgtcacgctgcttgagcgttacaacattgataccttcggcctc
aacgccgtggtgattggcgcatcgaatatcgtcggtcgtccaatgagcatggaactgttg
ctcgcaggttgcaccactaccgtgactcaccgtttcactaaaaatctgcgtcaccacgta
gaaaatgccgatctgttgatcgttgccgtcggcaagccgggctttattcctggtgactgg
atcaaagaaggcgcaattgtgattgatgtcggcatcaaccgtctggaaaatggcaaagtt
gtgggcgacgtcgtgtttgaagacgcggctaaacgcgcctcatacattacgcctgttccg
ggcggcgttggcccgatgacggttgccacgctgattgaaaacacgcttcaggcgtgcgtt
gaatatcatgatccacagggtgagtaa

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