Escherichia coli O152 H28 SE11 (commensal): ECSE_2941
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Entry
ECSE_2941 CDS
T00784
Name
(GenBank) gamma-glutamate-cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ecy
Escherichia coli O152:H28 SE11 (commensal)
Pathway
ecy00270
Cysteine and methionine metabolism
ecy00480
Glutathione metabolism
ecy01100
Metabolic pathways
ecy01240
Biosynthesis of cofactors
Module
ecy_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ecy00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ECSE_2941
09106 Metabolism of other amino acids
00480 Glutathione metabolism
ECSE_2941
Enzymes [BR:
ecy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
ECSE_2941
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GFIT
Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
BAG78465
UniProt:
B6I679
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Position
complement(3049006..3050562)
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGY
FRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALA
DAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTL
DSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL
EILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgtgggctggagcgcgaaactttgcgtgttaatgctgatggcacactggca
acaacaggtcatcctgaagcattaggttccgcactgacgcacaaatggattactaccgat
tttgcggaagcattgctggaattcattacaccagtggatggtgatattgaacatatgctg
acctttatgcgcgatctgcatcgttatacggcgcgcaatatgggcgatgagcggatgtgg
ccgttaagtatgccatgctacatcgcagaaggtcaggacatcgaactggcacagtacggc
acttctaacaccggacgctttaaaacgctgtatcgtgaagggctgaaaaatcgctacggc
gcgctgatgcaaaccatttccggcgtgcactacaatttctctttgccaatggcattctgg
caagcgaagtgcggtgatatctcgggcgctgatgccaaagagaaaatttctgcgggctat
ttccgcgttatccgcaattactatcgtttcggttgggtcattccttatctgtttggtgca
tctccggcgatttgttcttctttcctgcaaggaaaaccaacgtcgctgccgtttgagaaa
accgagtgcggtatgtattacctgccgtatgcgacctctcttcgtttgagcgatctcggc
tataccaataaatcgcaaagcaatcttggtattaccttcaacgatctttacgagtacgta
gcgggccttaaacaggcaatcaaaacgccatcggaagagtacgcgaagattggtattgag
aaagacggtaagaggctgcaaatcaacagcaacgtgttgcagattgaaaacgaactgtac
gcgccgattcgtccaaaacgcgttacccgcagcggcgagtcgccttctgatgcgctgtta
cgtggcggcattgaatatattgaagtgcgttcgctggacatcaacccgttctcgccgatt
ggtgtagatgaacagcaggtgcgattcctcgacctgtttatggtctggtgtgcgctggct
gatgcaccggaaatgagcagtagcgaacttgcctgtacacgcgttaactggaaccgggtg
atcctcgaaggtcgcaaaccgggtctgacgctgggtatcggctgcgaaaccgcacagttc
ccgttaccgcaggtgggtaaagatctgttccgcgatctgaaacgcgtcgcgcaaacgctg
gatagtattaacggcggcgaagcgtatcagaaagtgtgtgatgaactggttgcctgcttc
gataatcccgatctgactttctctgcccgtatcttaaggtctatgattgatactggtatt
ggcggaacaggcaaagcgtttgctgaagcgtaccgtaatctgctgcgtgaagagccgctg
gaaattctgcgcgaagaggattttgtagccgagcgcgaggcatctgaacgccgtcagcag
gaaatggaagccgcagataccgaaccgtttgcggtgtggctggaaaaacacgcctga
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