Escherichia coli O45 K1 H7 S88 (ExPEC): ECS88_0077
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Entry
ECS88_0077 CDS
T00830
Symbol
leuC
Name
(GenBank) 3-isopropylmalate isomerase subunit, dehydratase component
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ecz
Escherichia coli O45:K1:H7 S88 (ExPEC)
Pathway
ecz00290
Valine, leucine and isoleucine biosynthesis
ecz00660
C5-Branched dibasic acid metabolism
ecz01100
Metabolic pathways
ecz01110
Biosynthesis of secondary metabolites
ecz01210
2-Oxocarboxylic acid metabolism
ecz01230
Biosynthesis of amino acids
Module
ecz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ecz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ECS88_0077 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECS88_0077 (leuC)
Enzymes [BR:
ecz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ECS88_0077 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ECS88_0077 (leuC)
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Paralog
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CAR01443
UniProt:
B7MAJ7
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All DBs
Position
complement(81909..83309)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaagacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccacc
atggatcacaacgtctctactcagacgaaagacattaatgcctgcggtgaaatggcgcgc
atccagatgcaggagctgatcaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggcgtgaccttgccg
gggatgaccattgtctgcggcgactcacataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgggcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattattggtaaaaccggcagcgcaggcggtaccgggcatgtg
gtggaattttgcggcgaagcaatccgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcaatcgaaatgggcgcaaaagccggtctggttgcaccggacgaaaccaccttt
aactatgttaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggagcaactttcgataccgttgtcactctgcaa
gcagaagagatttcgccgcaggtcacctggggcaccaatccaggccaggtgatttctgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggtattccgctgacagaagtggctatcgac
aaagtgtttattggttcctgtactaactcgcgtattgaagatttacgcgcggcagcggaa
atcgccaaaggccggaaagtcgcgccaggcgtacaagcgctggtggttcccggctccggt
ccggttaaagcccaggcggaagcggaaggtctggacaaaatttttatcgaagctggtttt
gaatggcgcttgccaggttgttcaatgtgcctggcgatgaacaacgaccgcctgaatccg
ggcgaacgttgcgcctccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagtccggcaatggctgccgccgcggctgtgaccggacatttcgcc
gacattcgcaacattaaataa
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