Escherichia coli O45 K1 H7 S88 (ExPEC): ECS88_0089
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Entry
ECS88_0089 CDS
T00830
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ecz
Escherichia coli O45:K1:H7 S88 (ExPEC)
Pathway
ecz00300
Lysine biosynthesis
ecz00550
Peptidoglycan biosynthesis
ecz01100
Metabolic pathways
ecz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ecz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ECS88_0089 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECS88_0089 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ECS88_0089 (murF)
Enzymes [BR:
ecz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ECS88_0089 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
CAR01455
UniProt:
B7MAK9
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Position
97092..98450
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIKLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDCVLSVGKQSHAISTASGVGEHFSDKTALIARLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgatattctcaacggtgaactgcaaggtgca
gatattacccttgatgctgtaaccactgacacgcgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgtttcgatgctcatgattttgccgaccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggatattgatctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacaggttcctccggcaaaacctccgttaaagagatgacggcggca
attttaagccagtgcggcaacacactttatacggcaggcaatctcaataacgacatcggt
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggtgaaattgcctggactgtgagtctgactcgcccggaagcggcgctg
gtcaacaacctggcagcggcgcatttggaaggttttggctcgcttgcgggcgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccattatgaacgccgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cctaatgccgccaacagcgatttcaccgccaccaatatccatgtaacctcgcacggtacg
gaatttaccctgcaaacccctacaggtagcgtcgatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtctgttccccata
aaactggcagaaaaccagttgctgctcgacgactcctacaacgccaatgtcggttcaatg
accgccgctgttcaggttctggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaagcggcaaaa
gctgctggtattgactgcgtgttaagtgtgggtaaacaaagccatgctatcagcaccgcc
agcggcgttggcgaacatttttccgataaaactgcgcttatcgcgcgtcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgctgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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