Escherichia coli O45 K1 H7 S88 (ExPEC): ECS88_2729
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Entry
ECS88_2729 CDS
T00830
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ecz
Escherichia coli O45:K1:H7 S88 (ExPEC)
Pathway
ecz00230
Purine metabolism
ecz01100
Metabolic pathways
ecz01110
Biosynthesis of secondary metabolites
Module
ecz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ECS88_2729 (purL)
Enzymes [BR:
ecz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ECS88_2729 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CAR03993
UniProt:
B7MIP1
LinkDB
All DBs
Position
complement(2729061..2732948)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLLVHTIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTRLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEGFHVLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcctggttcacactatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctg
caacaggtaaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagc
gttgatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatctgcaggatgctttcacaaggcttggtcgtaat
ccgaacgacatcgaactgtatatgtttgcccaggcgaactccgagcactgccgccacaaa
atttttaacgccgactgggttatcgatggtgaacagcagccgaaatcgctatttaagatg
atcaaaaacaccttcgaaaccacgccggatcacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccggacgtggcgcaaagccgaaagctggtctggttggtttctccgtatccaacctg
cgaattcctggcttcgaacagccgtgggaagaagatttcggtaaacctgagcgcattgtt
accgcgctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggtcgcccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaat
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggtgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgttggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcgtcttctatggcatctggtcag
tctgatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcggg
cgcggcggtaaatttgaactgcgcgatatcctgagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcgccatacgcggtgattggtgaagcg
accgaagaactgcatctttctttgcacgatcgtcattttgataatcagccgattgatcta
ccgctggacgtactgcttggcaaaacgccgaagatgacccgcgatgtacaaacgctgaaa
gcgaaaggcgacgcgctggcccgtgaagggatcaccatcgctgacgcggtgaaacgcgtg
ctgcatctgccgaccgtggcggagaaaactttcctggtgaccatcggtgaccgcagcgta
accggcatggtagcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaattgt
gcggtcactaccgccagcctcgacagctactatggcgaagcgatggcaattggcgaacgt
gcgccagttgcgctgctggatttcgccgcttctgcccgtctggcggtcggtgaagcgtta
accaacatcgccgcaacgcagattggcgatatcaaacgcatcaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtg
ggcgaagaactttgtccggcgctgggcctgacgataccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgttgtcgctg
gtgatttccgcatttgcccgcgtggaagatgtacgtcacaccattacgccgcagctttct
accgaagataacgcactgttgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcactggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtt
gcccaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctg
gcgtatcacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgct
ggtcattgtggcattgacgcggatatcgccactctgggtgacgatcgcctggcggcgttg
tttaacgaagaactgggtgcggtgattcaggtgcgagccgctgaccgtgaagccgttgaa
gcggtactggcacagcatgggcttgctgattgcgtccattatgttgggcaggcggtttcc
ggtgaccgttttgtgattaccgccaacgggcagactgtatttagcgaaagccgcaccacg
ttgcgtgtctggtgggcagaaacgacctggcagatgcagcgtctgcgtgacaacccggag
tgtgccgatcaggagcaccaggcgaaatcaaacgacgccgatccgggcctgaatgtgaaa
ctgtcgtttgatatcaacgaagatgtggcagcaccgtttattgccactggcgcgcgcccg
aaagttgccgtactgcgtgagcagggtgtgaactcccatgttgaaatggcggcagctttc
caccgtgcgggcttcgatgctatcgacgtgcatatgagcgatctgctggctggacgcacg
ggcctggagggtttccacgtcctggtagcgtgcggtggtttttcctacggtgatgtgctg
ggcgctggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccatcgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccgggtagcgagttgtggccacgttttgtgcgtaac
acctccgatcgctttgaagcgcgtttcagtctggtagaagtaacccaaagcccgtcgctg
ctgttgcaggggatggtgggctcgcagatgccgattgctgtctctcacggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttct
ccgaatggtattacggcagtcacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcacgtaagcagttggggtaa
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