Escherichia coli O45 K1 H7 S88 (ExPEC): ECS88_4294
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Entry
ECS88_4294 CDS
T00830
Symbol
fadB
Name
(GenBank) fused 3-hydroxybutyryl-CoA epimerase and delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase and enoyl-CoA hydratase; 3-hydroxyacyl-CoA dehydrogenase
KO
K01825
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
5.3.3.8
]
Organism
ecz
Escherichia coli O45:K1:H7 S88 (ExPEC)
Pathway
ecz00071
Fatty acid degradation
ecz00280
Valine, leucine and isoleucine degradation
ecz00310
Lysine degradation
ecz00362
Benzoate degradation
ecz00380
Tryptophan metabolism
ecz00410
beta-Alanine metabolism
ecz00640
Propanoate metabolism
ecz00650
Butanoate metabolism
ecz00907
Pinene, camphor and geraniol degradation
ecz00930
Caprolactam degradation
ecz01100
Metabolic pathways
ecz01110
Biosynthesis of secondary metabolites
ecz01120
Microbial metabolism in diverse environments
ecz01200
Carbon metabolism
ecz01212
Fatty acid metabolism
Module
ecz_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
ecz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
ECS88_4294 (fadB)
00650 Butanoate metabolism
ECS88_4294 (fadB)
09103 Lipid metabolism
00071 Fatty acid degradation
ECS88_4294 (fadB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
ECS88_4294 (fadB)
00310 Lysine degradation
ECS88_4294 (fadB)
00380 Tryptophan metabolism
ECS88_4294 (fadB)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
ECS88_4294 (fadB)
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
ECS88_4294 (fadB)
09111 Xenobiotics biodegradation and metabolism
00362 Benzoate degradation
ECS88_4294 (fadB)
00930 Caprolactam degradation
ECS88_4294 (fadB)
Enzymes [BR:
ecz01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
ECS88_4294 (fadB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
ECS88_4294 (fadB)
5. Isomerases
5.1 Racemases and epimerases
5.1.2 Acting on hydroxy acids and derivatives
5.1.2.3 3-hydroxybutyryl-CoA epimerase
ECS88_4294 (fadB)
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.8 Delta3-Delta2-enoyl-CoA isomerase
ECS88_4294 (fadB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
3HCDH
ECH_2
NAD_binding_2
Motif
Other DBs
NCBI-ProteinID:
CAR05485
UniProt:
B7MHD1
LinkDB
All DBs
Position
complement(4261679..4263868)
Genome browser
AA seq
729 aa
AA seq
DB search
MLYKGDTLYLDWLEDGIAELVFDTPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSN
KAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCEC
VLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALK
IGLVDGVVKAEKLVEGAIAILRQAINGDLDWKAKRQPKLEPLKLSKIEAAMSFTIAKGMV
AQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVK
GKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLL
NKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRP
DTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAW
ASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGAGFRKIDKVMEKQFGWPMGPAYL
LDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKP
KKEEDVVVDDLLAKVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVY
GLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPA
RPVGDLKTA
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgctttacaaaggcgacaccctttaccttgactggctggaagatggcattgccgaactg
gtatttgataccccaggttcagttaataaactcgacactgcgaccgtcgccagcctcggc
gaggccatcggcgtgctggaacagcaatcagatctaaaaggactgctgctacgttcgaac
aaagcagcctttatcgtcggtgctgatatcaccgaatttttgtccctgttcctcgttcct
gaagaacagttaagtcagtggctgcactttgccaatagcgtgtttaatcgcctggaagat
ctgccggtgccgaccattgctgccgtcaacggctatgcgctgggcggtggctgcgaatgc
gtgctggcgaccgattatcgtctggcgacgccggatctgcgcatcggtctgccggaaacc
aaattgggcatcatgccgggctttggcggttctgtacgtatgccacgtatgctgggcgct
gacagtgcgctggaaatcattgccgccggtaaagatgtcggcgcggatcaggcgctgaaa
atcggtctggtggatggcgtagtcaaagcagaaaaactggttgaaggggcgatagcgatt
ttacgccaggccattaacggcgacctcgactggaaagcaaaacgtcagccgaagctggaa
ccgctaaaactgagcaagattgaagccgccatgagcttcaccatcgctaaagggatggtc
gcgcaaacggcggggaaacattatccggcccccatcaccgcagtaaaaaccattgaagct
gcggcccgttttggtcgtgaagaagccttaaacctggaaaacaaaagttttgtcccgctg
gcgcataccaacgaagcccgcgcactggtcggcattttccttaacgatcaatatgtaaaa
ggtaaagcgaagaaactcaccaaagatgttgaaaccccgaaacaggccgctgtgctgggc
gcaggcattatgggcggcggcatcgcctaccagtctgcgtggaaaggcgtgccggttgtc
atgaaagatatcaacgacaagtcgttaaccctcggcatgaccgaagccgcgaaactgctg
aacaagcagcttgagcgcggcaagatcgatggtctgaaactggctggcgtgatctccaca
attcacccaacgctcgactacgccgggtttgaccgcgtggatgttgtggtagaagcggtt
gttgaaaacccgaaagtgaaaaaagccgtgctggcagaaaccgagcagaaagtacgcccg
gataccgtgctggcgtctaacacttcaaccattcctatcagcgaactggccaacgcgctg
gaacgtccggaaaacttctgcgggatgcacttctttaacccggtgcaccggatgccgttg
gtggaaattattcgcggcgagaaaagctccgacgaaaccatcgcgaaagtcgtcgcctgg
gcgagcaagatgggcaagacgccgattgtggtcaacgactgccccggcttcttcgtcaac
cgtgtgctgttcccctatttcgccggtttcagccagttgctgcgcgacggcgcgggtttc
cgcaagatcgacaaagtgatggaaaaacagtttggctggccgatgggtccggcatatctg
ctggatgttgtgggcattgacaccgcgcatcacgctcaggctgtcatggcagcaggcttc
ccgcagcggatgcagaaagattatcgcgatgccatcgacgcgctgtttgatgccaaccgc
tttggtcagaagaacggcctcggtttctggcgttataaagaagacagcaaaggtaagccg
aagaaagaagaagatgtcgtcgttgacgacctgctggcaaaagtgagccagccgaagcgc
gatttcagcgaggaagagattatcgcccgcatgatgatcccgatggtcaacgaagtggtc
cgctgtctggaagagggcattatcgccactccggcagaagcggatatggcgctggtctac
ggcctgggcttccctccgttccacggcggcgcgttccgctggctggacaccctcggcagc
gcaaaatacctcgatatggcacagcaatatcagcacctcggcccgctgtatgaagtaccg
gaaggtctgcgtaataaagcacgtcataacgaaccgtactatcccccggttgagccagcc
cgtccggttggcgacctgaaaacggcttaa
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