Enterobacter ludwigii EcWSU1: EcWSU1_00625
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Entry
EcWSU1_00625 CDS
T01652
Symbol
thrA
Name
(GenBank) Bifunctional aspartokinase/homoserine dehydrogenase 1
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
eec
Enterobacter ludwigii EcWSU1
Pathway
eec00260
Glycine, serine and threonine metabolism
eec00261
Monobactam biosynthesis
eec00270
Cysteine and methionine metabolism
eec00300
Lysine biosynthesis
eec01100
Metabolic pathways
eec01110
Biosynthesis of secondary metabolites
eec01120
Microbial metabolism in diverse environments
eec01230
Biosynthesis of amino acids
Module
eec_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
eec_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
eec_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
eec00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EcWSU1_00625 (thrA)
00270 Cysteine and methionine metabolism
EcWSU1_00625 (thrA)
00300 Lysine biosynthesis
EcWSU1_00625 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
EcWSU1_00625 (thrA)
Enzymes [BR:
eec01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
EcWSU1_00625 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
EcWSU1_00625 (thrA)
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Ortholog
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GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AEW72065
UniProt:
G8LLY1
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All DBs
Position
652552..655014
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AA seq
820 aa
AA seq
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MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNLSDAERIFAELLQGLAEAQPGFPLAQLKSFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGLLEARGHNVSVIDPVEKLLAVGHYLESTVDIAESTRRIAASKIP
SDHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIGASTD
EDGLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQGDCLRARRALEEEFYLELKEELLEPLSIQERLAVISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVVHQMLFNTDQVIELFLIGVGGVGGAL
LEQVKRQQEWLKKKHIDLRVCGIANSKALLTNVHGLNLENWQAELNDAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSNQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRLAASKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRAA
RELGYTEPDPRDDLSGMDVARKLLILVRETGRELELSDIVIEPVLPAGFDDSGDVNTFMA
NLAQLDDAFAARVAKARDEGKVLRYVGNIEDDGMCRVKIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatatcctggagagcaacgccaggcaggggcaggtcgcgaccgtgctctctgccccg
gcaaaaatcaccaaccacctggtggcgatgattgaaaagaccatcggtggccaggatgca
ctcccgaacttgagcgacgccgagcgtatcttcgctgagctgctgcaggggctggcggag
gcgcagccgggtttcccgctcgcacagctgaaatcgtttgttgagcaagagttcgcccaa
atcaaacacgtgctgcacggtatcagccttttaggtcagtgcccggacagcatcaacgcg
gcgttaatctgccgtggtgaaaaattgtcgattgccatcatggcgggcctgctggaagcg
cgtggtcacaatgtgtcggttatcgatcccgttgaaaaactgctggcagtgggccactac
ctcgagtctaccgttgatatagccgaatcaacccgtcgcattgccgcgagcaaaattccg
tctgaccatatgatcctgatggcgggcttcaccgccggaaacgagaagggtgaacttgtc
gtactgggccgtaacggctccgactactctgctgccgtgctggcagcctgtttgcgcgcc
gactgttgtgagatctggactgacgtcgacggtgtatacacctgcgatccgcgccaggta
ccggacgccaggctgctgaagtcgatgtcataccaggaagcgatggagctttcctacttc
ggcgctaaagttcttcaccctcgcaccatctctcccattgcccagttccagatcccttgc
ctgattaaaaacaccggtaacccgcaagcgccgggcacgctgattggcgccagtaccgat
gaagacggcctgccggtgaaaggcatttctaacctgaacaatatggccatgttcagcgtt
tccggcccgggaatgaaaggcatggtcggtatggcggcccgcgttttcgcggccatgtcc
cgcaacggtatctcggttgtgctgatcactcagtcctcttctgaatacagcatcagcttc
tgcgtaccgcagggggattgcctgcgcgcccgtcgtgcgctggaagaagagttttacctt
gagctgaaagaagagttgctggagccgctttctatccaggaacgcctggcagtcatctcg
gtagtgggcgacggtatgcgtacgctacgcggtatctcggccaaattctttgccgcgctg
gccagggccaacatcaacattgtggccattgcccaggggtcatctgagcgttcaatctcg
gtggtcgttgacaacgacgatgcgacaaccggcgttcgcgtggttcatcagatgctgttc
aacaccgatcaggtgatcgagctgttcctgattggcgtgggcggtgtgggtggcgcgctg
ctggagcaagtgaagcgtcagcaggagtggttgaagaaaaagcacattgatctgcgcgtg
tgcggtatcgcgaactctaaagcgctgctgaccaacgttcatggcctgaacctggaaaac
tggcaggctgagctgaatgatgccaaagagccctttaatctgggccggttgatccgcctg
gtgaaagagtatcacctgcttaacccggtcattgtcgactgtacctcgaaccaggcggtg
gccgatcagtacgccgatttcctgcgcgaaggtttccacgtggtgacgccaaacaaaaag
gccaacacctcgtcgatggattactatcaccagctgcgtctggcggcgagcaagtcacgg
cgtaagttcctctacgacaccaacgtgggcgcgggcctgccggtgatcgagaacctgcaa
aacctgctgaacgcgggggatgaactgcagcgtttctccggcattctttccggctcgctg
tcgtttatcttcggcaagctggatgagggcatgagcctgtcggaagcgacccgtgccgcg
cgtgaactggggtacaccgagccggatccgcgagacgatctctccggtatggatgtggcg
cgtaagttgctcatactggtgcgtgaaacgggccgtgagctggagctttccgatatcgtg
attgagcctgttctgcctgccgggtttgacgacagcggtgacgtgaacacctttatggcc
aatttagcgcagctagacgacgcctttgccgcacgcgttgcgaaagcccgtgatgaaggt
aaggtattgcgctatgttggcaatattgaagacgatggtatgtgccgcgtgaagattgct
gaagtggatggcaacgacccgctgttcaaagtaaaaaacggcgaaaacgccctcgcgttt
tacagccactattatcagccactgccgctggtgcttcgcggctatggcgcagggaatgat
gttaccgcggcgggtgtatttgccgatttgctgcgtaccctgtcatggaagttaggagtt
taa
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