Enterobacter ludwigii EcWSU1: EcWSU1_00699
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Entry
EcWSU1_00699 CDS
T01652
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
eec
Enterobacter ludwigii EcWSU1
Pathway
eec00300
Lysine biosynthesis
eec00550
Peptidoglycan biosynthesis
eec01100
Metabolic pathways
eec01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
eec00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EcWSU1_00699 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EcWSU1_00699 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EcWSU1_00699 (murF)
Enzymes [BR:
eec01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EcWSU1_00699 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
AEW72139
UniProt:
G8LMQ9
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Position
735130..736488
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AA seq
452 aa
AA seq
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MISITLSQAAAVLQGELLGHDLTIEAVTTDTRKVTPGCLFVALKGERFDAHDFAQQAREN
GAGALLVSRKLAVDLPQIVVKDTRLAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHEFAVIELGANHQGEIAWTVRLTRPEAAL
VNNLAAAHLEGFGSLEGVAKAKGEIYTGLPEDGIAIMNADNNDWLNWQQIIGSRKTWRFS
PNAANSDFTATNIHVTSHGTEFTLNTPTGGIEVLLPLPGRHNIANALAAAALSMAVGASH
QAIKTGLANLKAVPGRLFPIQLAENKLLLDDSYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGDESEACHVQVGDAAKAAGIDCVLSAGKLSQAISHASGVGEHFADKAALIERLKAL
MTEKQIVTVLVKGSRSAAMEEVVHALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcatcaccttaagtcaggccgctgcggtactgcagggcgagctgctgggtcac
gatctgaccatcgaggccgtgacgaccgatacccgcaaagtgaccccgggttgtctgttt
gtggcgctgaagggcgaacgttttgacgcgcatgattttgcacaacaggccagggagaat
ggtgcaggggcgctgctggtcagccgtaaactcgctgtcgatctgccgcagatcgtggtg
aaagatacccgtctggcattcggcgagctggcggcctgggttcgtcagcaggtgccgacg
cgcgtcgtcgcgctgaccggttcatcaggcaaaacctctgtgaaagagatgactgcggcc
atcctgagccagtgcggaaatacgctttatacagcaggcaaccttaacaatgatatcggc
gtgccgatgacattacttcgcctgaccaaagagcatgaatttgccgtgatcgagttaggg
gcaaaccaccagggcgaaatcgcctggaccgtgagactgacgcgcccggaagcagcgctg
gtgaataacctggccgctgcacatctggaaggttttggttcgctggaaggcgtggcgaaa
gctaaaggcgagatctataccggcctgccggaagacggtatcgccattatgaatgccgac
aacaatgactggctgaactggcaacagatcattggttcccgcaagacctggcgcttctcg
ccgaacgcggccaacagtgattttaccgcgaccaatattcatgtgacttcgcatggcacg
gaattcacccttaataccccaaccggtggcattgaggtgcttctgccattgccgggtcgt
cataatatcgccaatgcgctcgcggcagcggcgctgtcgatggcggttggtgcgtcgcat
caagcgattaaaaccggtctggcaaatttaaaagccgtgccggggcgtctgttcccgatc
cagcttgcggaaaacaaactgcttctggatgactcctataacgcgaacgtcggctcaatg
accgcggcggtgcaggtgttgtctgagatgccaggttatcgcgtgctggtggtgggcgat
atggctgagctgggtgatgaaagcgaagcctgtcatgtccaggtgggggacgcggcgaaa
gcggcaggtattgattgcgtgctgagcgctggaaaactgagccaggcgattagccatgcc
agcggtgttggcgagcactttgccgataaagccgcgctgattgaacgccttaaggcattg
atgacagaaaaacaaattgtgactgtgttagtgaaaggttcacgtagtgccgccatggaa
gaggttgtgcacgcattacaggagaacgggacatgttag
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