Enterococcus faecium Aus0004: EFAU004_00217
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Entry
EFAU004_00217 CDS
T01772
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
efc
Enterococcus faecium Aus0004
Pathway
efc00300
Lysine biosynthesis
efc00550
Peptidoglycan biosynthesis
efc01100
Metabolic pathways
efc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
efc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EFAU004_00217
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EFAU004_00217
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EFAU004_00217
Enzymes [BR:
efc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EFAU004_00217
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3323
Motif
Other DBs
NCBI-ProteinID:
AFC62303
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Position
211787..213199
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AA seq
470 aa
AA seq
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MRTRRLGQTLFSQPFLGEISMNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVP
LAGTRDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGA
EVVAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVPAD
EPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNVTNAL
IAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMGLVLDTF
KNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHALKEELNQKY
PQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgcgaacccgccgtttaggccaaacgcttttttcacaaccttttttaggagagatctca
atgaatctaacaatacaagaaattgcacaagccgtgggcagcgaatgctctgcactgaca
aagattaccaatgtcgaatttgacagccggaagataaccgaaggaagtttattcgttcct
cttgctggtacgcgagatggacatgaatttatccagcaagcgatcacaaacggagcatct
gcttcattttggagcttgcctgttgaacaagctccaaaaaattttccagttattcctgta
gcagatcctttgaaagccatgcagcaattggcaacctattacttggaaaaagtaggcgca
gaagtcgttgcaattacaggaagcaatggtaaaaccaccacgaaagatctaaccgcgtct
gtcttgtctgaaaaatacaaaacatataagacgcaaggaaattacaacaataatattggt
cttccttacacgattttgcacatgccccaagatacagaaaagatcgttttggaaatgggc
atggatcacgccaatgaaatcacggaactttcacttatggctcaaccaaaagctgcagca
atcacaatgatcggtgaagcacacatagaaaatcttgggtcgcgagaaggaatcgctaaa
gccaaaatggaaatcactgacggacttgtatcagacggattactcgttgtgcccgcagat
gaaccgttgctgacacctttaacggcaacattagtacaaacagtcacaacattcggtatt
ggaaatggcgatgttcatgcggaagtgacagcaaaaggaaaagcacaaaccgattttgta
gtagaaggagaaacatttacgatcccgctgcctggaagttataatgtaacgaatgctttg
attgcgtatacgatcgggcgcttctttggactgtccatacctgagatacgccaagggctc
gcccatgtttctatcactcaaaacagaaccgaatggctaacggcaggaaatggtgcagct
attttgagcgatgtctacaatgcaaatccaacagccatgggactggtattagatactttt
aaaaatctgccaacaaaaggacgcagaatcgctgtgttagcagatatgctggaattaggg
aaagagtctttaaatatgcatgcgcaaatgagtgaacatatcgatcctgagaaattcgcc
atgattttcctttatggggaacaaatgcatgcactaaaagaagaattgaaccaaaaatac
ccccaactacctgtgttctattttgaaaaagaaaagaataaattgattgatgctatcaaa
caaaatcttgcagcaacagatagtattatgctaaaaggcagcaacagcatgggcttattt
gaagtggtagaacaacttcagcaaatgaaataa
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