Escherichia fergusonii: EFER_0108
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Entry
EFER_0108 CDS
T00811
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
efe
Escherichia fergusonii
Pathway
efe00300
Lysine biosynthesis
efe00550
Peptidoglycan biosynthesis
efe01100
Metabolic pathways
efe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
efe00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EFER_0108 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EFER_0108 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EFER_0108 (murF)
Enzymes [BR:
efe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EFER_0108 (murF)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
CAQ87691
UniProt:
B7LWE9
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Position
116619..117977
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELKGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNANNSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHVISTTSGVGEHFADKTALITHLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgatattctcaacggtgaactaaaaggggca
gatatcacccttgatgctgtaaccactgacacacgaaaactgacgccgggttgcctgttt
gttgccctgaaaggcgaacgtttcgatgcccatgattttgctgaccaggcgaaagctggc
ggtgcgggtgcactactggttagccgtccgctggatatcgatctgccgcagttaatcgtc
aaggatactcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgaccggttcctccggcaaaacctccgttaaagagatgacggcggcg
attttaagccagtgtggcaacacgctttatacggcaggcaatctcaacaacgacatcggt
gtaccgatgacgctgttgcgcttaacgccagagtacgattacgcagttattgagcttggt
gcaaaccatcagggtgaaattgcctggactgttagccttactcgcccggaagcggcgctg
gtcaacaacctggcagcggcgcatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccattatgaatgccgac
aacaacgactggctgaactggcagagtgtgattggctcacgcaaagtgtggcgcttctca
ccgaatgctaacaacagcgatttcaccgccaccaatatccacgtgacctcgcacggtacg
gaatttacgctgcaaaccccaacgggtagcgtcgatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctattaaagcggggctggcaaatctgaaagctgtccctggccgtctgttccccatt
caactggcggaaaatcagttgctgctcgacgactcctacaacgctaacgtcggctccatg
accgccgctgttcaggtactggctgaaatgccgggctaccgtgtgctggtggtgggcgat
atggcagaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaagcggcgaag
gcggctggtattgaccgcgtgttaagcgtgggtaaacaaagccatgttatcagcaccacc
agcggcgttggcgaacattttgctgataaaactgcgttaattacgcatcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgctgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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