Escherichia fergusonii: EFER_0518
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Entry
EFER_0518 CDS
T00811
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
efe
Escherichia fergusonii
Pathway
efe00230
Purine metabolism
efe01100
Metabolic pathways
efe01110
Biosynthesis of secondary metabolites
Module
efe_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
efe00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
EFER_0518 (purL)
Enzymes [BR:
efe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
EFER_0518 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CAQ88066
UniProt:
B7LV08
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Position
516020..519907
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
HEQWQQVTAELHDRMMETVFSALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGSEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLVVTLAEMAFA
GHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFNESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacaatatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccacgccccgcaaggtaaactcctgctggtgaccccgcgt
cctggtaccatctctccctggtcttcgaaagcgaccgatatcgcccataactgcgggctg
caacaggtaaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgacc
catgaacaatggcagcaggtgaccgctgaactgcacgaccgcatgatggaaacggtcttt
tctgctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagc
gttgatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcgctggcggaagatgaaattgactatctgcaggatgcgttcacaaagctgggtcgtaac
ccgaacgacatcgagctgtatatgttcgcccaggcgaactctgagcactgccgtcataaa
atttttaacgccgactggattatcgacggtgaacagcaaccgaaatcgctgttcaagatg
atcaaaaataccttcgaaaccacgccggatcacgttctttctgcttataaagataacgcc
gccgtgatggaaggttccgaagtgggccgctactttgctgaccacgaaacgggccgctac
gacttccatcaggaaccggcgcacatcctgatgaaagtagaaacccacaaccacccaacg
gcgatttctccgtggccgggcgcagctaccggttccggcggtgaaatccgcgatgaaggt
gccaccggccgcggcgcgaagccgaaagctggcctggtcggtttctccgtatccaacctg
cgtattcctggctttgaacaaccgtgggaagaagatttcggtaagcctgagcgcattgtc
actgcgctggatatcatgaccgaaggcccgctgggcggcgcggcatttaacaacgaattt
ggtcgtccggcactgaacggctacttccgtacctatgaagaaaaagtgaacagccacaac
ggcgaagagctgcgcgggtatcacaaaccgatcatgctggcgggtgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgtcggtgcgaaactggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcctcttccatggcctccggccag
tctgacgcggatctcgatttcgcgtccgttcagcgcgataacccggaaatggaacgtcgt
tgccaggaagtgatcgaccgctgctggcagcttggcgacgcgaacccgattctgtttatc
cacgacgtcggcgcaggcggtctttctaacgccatgccggagctggtgagcgacggcggg
cgcggcggtaaatttgaactgcgcgatatcctgagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaatgaatcccaggaacgctacgtgctggcagttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcaccgtacgcggtgattggtgaggcc
accgaagaattacatctttctctgcacgatcgtcattttgataatcaacccatagatcta
ccgctcgacgtactgcttggcaaaacgccgaagatgacccgcgatgtgcaaacgctgaaa
gcgaaaggcgacgcgctggcccgtgaagggatcaccatcgctgacgcggtgaaacgtgtg
ttacatctgccgactgtggcggagaaaacctttctggtgaccatcggcgatcgcagcgta
accggcatggtggcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgc
gcagtcactaccgccagcctcgacagctactacggtgaagcgatggcgattggcgaacgt
gcgccggttgcgctgctggatttcgctgcctctgctcgtctggcggttggtgaagcgtta
actaacattgccgcaacgcagattggcgatatcaaacgcatcaaactttccgccaactgg
atggcagcagcaggtcatccaggtgaagacgcgggcctgtatgaagccgttaaagcggtg
ggcgaagagctttgcccggcgctgggcctgactatcccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtagcgaagagcgcgaaatgacctcgccgctttcgctg
gtgatttctgcatttgcccgcgtggaagatgtgcgtcacaccatcacgccgcagctttct
accgaagataacgcactgctgctgattgatctgggcaaaggcaataacgcgctgggtgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgatgtc
gcgcaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctc
gcgtatcacgaccgctctgatggcgggctggtggtaacgctggcggaaatggcctttgct
ggtcattgcggcattgacgcggatatcgccactctgggtgacgatcgcctggcggcgttg
tttaacgaagaactgggggcggtgattcaggtgcgcgctgctgaccgtgaagcggtcgaa
gcggtactggcacagcatggccttgctgattgcgtccattatgttggtcaggcggtttcc
ggtgaccgttttgtaattaccgccaacgggcagactgtattcaacgaaagccgcaccacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgccgatcaggaacatcaggcgaaatctaacgacgccgatccgggcctgaatgtgaaa
ctgtcgttcgatatcaacgaagatgtggcagcaccgtatattgccaccggtgcgcgtccg
aaagttgccgtgctgcgtgagcagggtgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcaggcttcgatgcaatcgatgtgcatatgagcgacctgctggctggacgcacg
ggcctggaggatttccacgctctggtagcgtgcggcggtttctcctacggtgatgtgctg
ggtgctggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgtgaactgatcccgggtagcgagttgtggccacgtttcgtgcgtaac
acctccgatcgctttgaagcgcgtttcagcctggtagaagtgacacaaagcccgtcgctg
ctgttgcaagggatggtgggttcgcagatgccgattgctgtctctcacggcgaagggcgc
gtggaagtgcgcgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttct
ccgaatggtattacggcggtcacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagtaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgtattttccgcaatgcgcgtaagcagttggggtaa
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