KEGG   Enterococcus faecium ATCC 8459 = NRRL B-2354: M7W_1831
Entry
M7W_1831          CDS       T02454                                 
Name
(GenBank) Multimodular transpeptidase-transglycosylase, Penicillin-binding protein 1A, 1B (PBP1)
  KO
K05366  penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
Organism
efm  Enterococcus faecium ATCC 8459 = NRRL B-2354
Pathway
efm00550  Peptidoglycan biosynthesis
efm01100  Metabolic pathways
efm01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:efm00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    M7W_1831
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    M7W_1831
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:efm01003]
    M7W_1831
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:efm01011]
    M7W_1831
Enzymes [BR:efm01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.28  peptidoglycan glycosyltransferase
     M7W_1831
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     M7W_1831
Glycosyltransferases [BR:efm01003]
 Polysaccharide
  Bacterial polysaccharide (excluding LPS)
   M7W_1831
Peptidoglycan biosynthesis and degradation proteins [BR:efm01011]
 Peptidoglycan biosynthesis and degradation
  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
   M7W_1831
SSDB
Motif
Pfam: Transgly Transpeptidase SRP1_TIP1 RICH
Other DBs
NCBI-ProteinID: AGE30445
LinkDB
Position
complement(1688060..1690441)
AA seq 793 aa
MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKILLGILSFFCILFLAGV
GLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKREKISANELPKTLEDAIVS
VEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQLIKLSFFSTSAEDQTLKRKAQ
EAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETASEMYFGKKLSELSLPQTALLAGM
PQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQTEYDQAVNVPVTDGLQELTQSDDNT
KIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLDLDAQKKLYDIVNTDQYVSYPDDEMQV
ASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLAVNTSRDFGSTMKPVTDYGPAFEYLKYST
GKTITDAPYNYEGTSTPVGNWDNQYMGTITLRQALYLSRNVPAVKLFNEVGSDKVASFLK
NLGIEYSTIHQSNAISSNTEEQDGTKYGASSLKMAAAYAAFANGGTYYKPQYVNKIVFQD
GTEETYEPDGKTAMSPETAYMITDILKDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYA
KLGISSGVYPDILFAGYTPNYSISVWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVT
NTDWEMPSGLIRVGGELYYKDQYTARSNVVTPSTTIPSSSYVQTPGSSTTETTTQSSSST
SQSESTAESSKESTTAETSEPASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAAND
HTPSSSTSASGNR
NT seq 2382 nt   +upstreamnt  +downstreamnt
atggcaaatgaacaaactagaagctctagacgacagaaacagcctactcctaaaaagagt
gtgaagaagaattctggcaaaggttctggaaagtcctctggaacacataaaaaaggatta
tttatcaagatccttttaggaatactctcatttttctgtatcctctttttagcaggtgta
ggacttttctggtattacgcaaaagatgcgcccgaattgacggataaaaaattagacgct
accgtatcttccaaactatatacacaagatggcgaactattcgaagatttaggcgcagaa
aagcgtgaaaaaatttctgcgaatgaattaccgaaaacattagaagatgcgatcgtgtcg
gtagaagatcgccgtttttataaacacatcggggttgaccctattcggatcatcggttct
gccctctctaactttacctctggcggactgcaaggcggaagtactttgacacagcaattg
atcaaactttccttcttctccactagtgcagaggatcagaccctgaaacgcaaggcccaa
gaagcgtggatggctgtaagattggaacaaaaaaaatcgaaacaagagatcttgacctac
tacgtaaataaagtgtatatgtcaaacggcttgtacgggatggagacagcttctgagatg
tactttggtaagaaattatcagaactttctttaccgcaaacagcattgcttgctgggatg
cctcaagccccttccgcctatgatccttatgtttatccagatcaggcgaagaaaagacga
gatactgttttgtatacgatgcttcaaaacgaaaaaatctctcaaacagagtatgatcaa
gctgttaatgtaccggtaacggatggtctgcaagaactaactcaatccgatgacaatact
aagatcgtcgataattatgtcaaagaagtcatcaatgaagtacaagaaaaaacagataag
aatgtctacacagacggtttagagatttatacgaatttggatctggacgcccaaaagaaa
ctatatgatatcgtcaacacggatcagtatgtctcttacccagacgacgagatgcaagtt
gcctccacccttatcgacaccaataccgggaaagtaaaagcccagattggcggacgtcac
atcgcagaagacgtaactttaggcaacaacttagcagtgaatacttcccgtgattttggt
tctacgatgaaacctgtcacagattacggaccagcttttgaatatttgaaatattctact
ggaaaaactattactgacgcaccgtataactatgaagggacttcgactcctgtaggaaac
tgggataatcaatatatgggcaccattactttacgccaagcactttacttatcccgtaat
gttccagcagtcaaattattcaatgaagtcggttcagataaagtggcatctttcttaaaa
aatcttgggatcgaatacagtacgatccatcaatcgaatgcgatctctagtaatacggaa
gaacaagatgggacaaaatacggagcttcttccttaaaaatggcagcagcctatgcggct
ttcgccaatggagggacttattacaaacctcaatatgttaataaaatcgtcttccaagac
ggaacagaagaaacttatgagccagatggaaaaacagccatgtctccagaaacagcttat
atgatcacagacattttaaaagatacgatcactgaaggtactggtacgaatgcgcaaatc
gctgggttatatcaagccggtaagaccggaacatctaattacacagatgacgagtatgca
aaacttggtatttcttctggggtgtatccagatatcctatttgcgggctatacgccaaat
tattcgatttccgtgtggacaggttacaataaaaaaatgacacctgtcacttcagaatcg
tcacacgtagcctctgatgtttatcgcgagcttatgcagtatgtttcagctaacgtgaca
aatacagactgggagatgccaagcggattaattcgtgtgggcggtgaactgtactacaaa
gatcaatatacagctagatcgaatgtagttacaccatcaacaactattccatcttccagc
tatgtccagactcctggaagctcaacaacagagacaacgactcaaagctctagctctact
agtcaaagtgaatcaactgctgagtcctcaaaagaaagcacgacagcagaaacaagcgag
ccagcgtcttcaacaacggttccttcttcttcatccgaagaaagctcgacaccgtcttca
tctgctcctcctgcttcttccagtgagccagcaactagcggagcggatgctgcaaatgac
catacaccatccagtagcacctcagcttctggaaacagatag

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