Enterococcus faecium ATCC 8459 = NRRL B-2354: M7W_332
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Entry
M7W_332 CDS
T02454
Name
(GenBank) Glutathione biosynthesis bifunctional protein gshF
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
efm
Enterococcus faecium ATCC 8459 = NRRL B-2354
Pathway
efm00270
Cysteine and methionine metabolism
efm00480
Glutathione metabolism
efm01100
Metabolic pathways
efm01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
efm00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
M7W_332
09106 Metabolism of other amino acids
00480 Glutathione metabolism
M7W_332
Enzymes [BR:
efm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
M7W_332
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
GARS_A
RimK
ATPgrasp_ST
Topo-V_HhH_2_2nd
Dala_Dala_lig_C
R2K_3
R2K_2
LUC7
Motif
Other DBs
NCBI-ProteinID:
AGE28980
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Position
105769..108036
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AA seq
755 aa
AA seq
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MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPAIFGDRSYHPYIQTDFS
ETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLSMPPALPEKDEAIIIAKLK
NFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLFSHQEEFQDFSEFKTELYLKT
ARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRSIRNSALGYTNHPNVKVSYASMK
QYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADLATTGVRYIELRNIDLNPYARLGIN
PEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRNNKVALEQPSDQTEFHQEGREILEGMK
QMLVELDWLDSLYLVEEALTQMDHPEQTLAAKLYQEAQLSSQQEVAVALGHQYYKESHER
PYQLAGFREMELSTQIFMFDAIQKGVQVKVLDESDQFLRLQFQDHVEYVKNANMTSKDSY
IVPLIMENKTVTKKVLKEAGFRVPGGAEFSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGI
TIFKEGASLEDYQAGLAIAFREDSSVLVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGD
GIRTVKELVEEKNSDPLRGTNHRAPLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRE
NSNISTGGDSIDMTDEFSEAYKKIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGII
EANFNPAMHMHVYPFAGKGRRLTMNVLKLLYPEVF
NT seq
2268 nt
NT seq
+upstream
nt +downstream
nt
atgatgaattttaagcaattattattgcatgtcaatgcgcgcccttttatcgaccaagct
cgatttggtatagaacgggaaggacagcgggttgatcttgcaggaaatctagcaaaaacc
gatcatccagcaatctttggcgatcgatcctatcacccctatatccaaacagattttagc
gaaacacagacagagatgatcactcctgttaccgattctattcccgaattatttcagtat
ctcgctgctgtttatgatgtgactgctcgttctataccgaaagaagagatgatctggcca
ttaagtatgccacctgccttaccggaaaaagacgaagcgatcattattgcaaaattaaaa
aatttcgaagatgtcttgtatcgacgttatttagcaaaagaatacgggaagcgaaaacag
atggtaagcggtatccatttcaattttgaatttggcgatgagttgctaagaacattgttc
agccatcaggaagaatttcaagatttttccgaattcaaaacagaactttatttgaaaacg
gcgagaaactttatgcgctatcgctggatgatcacttatttattcggtgcttcaccaatg
agtgagaagaactactttttagatgaatcacatccgcaagaacctgttcgcagtattcgt
aacagtgcgctgggctatacgaatcatccaaatgtgaaagtttcctatgcttctatgaaa
cagtatttagcagatatcgagcgaatgatcgaagaagggaaactttcggaggagaaagaa
ttttatacaccgcttcgtttccgaggcggaaagaaagtcgcagatttagcaacaacaggt
gttcgttatattgaattgcggaatatcgatttgaatccttatgcaagattgggtatcaat
ccagagcaagttcggttcttacaattattcctgatgtacatgttatggacagaagaaaaa
gaagactgtgaccaatgggtagcagaaggtacgactcgaaataacaaagtagcactagaa
caaccatcagatcaaacagaatttcatcaagaaggtagagaaattcttgaagggatgaag
caaatgctggttgaattggattggttggattctctttatttagtagaggaagcattgact
caaatggatcatcctgaacaaacgttagcagcgaaactctatcaagaagcacagctatcg
agtcagcaagaagttgctgtggcattgggacatcaatattataaagaaagccatgaacgt
ccctatcagttggccggttttcgcgaaatggaactttctactcagatatttatgttcgat
gccatccaaaaaggtgtccaagtcaaagtattagatgagtcggatcaatttttgcgtctg
caattccaagaccatgtagaatatgtgaaaaatgcaaacatgacaagtaaggacagctat
atcgtcccacttatcatggaaaacaaaacagtaacgaaaaaagtcttaaaagaagctggg
ttccgggtaccaggaggcgcagaattttcatccatggaagaagcggtaaaagcttatccg
agatttgccgagcaggcatttgtgatcaaacctaaatcaaccaattacgggttaggtatc
acgattttcaaggaaggagctagtctggaagattatcaagcaggtttagccattgctttt
cgtgaagacagttcggttttagtagaagaatttatgccgggaacggaatatcgtttcttt
gtgatcgacggagaagtccaagccatcatgttgcgagtccctgctaatgttattggtgac
ggtatccgaacagtgaaagaacttgttgaagaaaaaaatagtgaccctttgcgtggaacg
aatcatcgtgcacctttagaattgatccaattaggtgaattagaacaattgatgttgaaa
gaacaagggttgacgatcgaatcagttccccaagccaatcaaattgtttatctaagggag
aactcaaatatcagtacaggtggtgattcgatcgatatgactgatgaattttctgaagct
tacaaaaaaatcgccgtttctgcggtagaagcactaggagctaagattagtggtatcgat
ttgattataccagataaagaaatcgatcctacaactgataaaaaagcatatgggatcatc
gaagcaaatttcaatccagccatgcatatgcatgtttatccctttgcaggaaaaggcaga
agattgacgatgaatgtattgaaattgttatatcctgaagtattttaa
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