Epinephelus fuscoguttatus (brown-marbled grouper): 125879176
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Entry
125879176 CDS
T08419
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
efo
Epinephelus fuscoguttatus (brown-marbled grouper)
Pathway
efo04217
Necroptosis
efo04620
Toll-like receptor signaling pathway
efo04621
NOD-like receptor signaling pathway
efo05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
efo00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
125879176 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
125879176 (tyk2)
04621 NOD-like receptor signaling pathway
125879176 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
125879176 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
efo01001
]
125879176 (tyk2)
Enzymes [BR:
efo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
125879176 (tyk2)
Protein kinases [BR:
efo01001
]
Non-receptor tyrosine kinases
JAK family [OT]
125879176 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
SH2
Kdo
Kinase-like
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
125879176
NCBI-ProteinID:
XP_049416794
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All DBs
Position
LG19:21149100..21160427
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AA seq
1166 aa
AA seq
DB search
MSRSGWSKRSRQGAFPGLPDPPQGPGIHVYLFCSKEGERYLSHTNGGVTAEDLCISAAEA
VGITPLCHVLFALYNPQSRCWYSPNHDFNPDNSSLVLHYCMRFYFRNWHGLNQKEPAVSR
YSLRSGTNQGGSPLLEIASLQYLFSQAKYEFVNEVIQMEDLQSAEDISRFKNESLGMAVL
QLSHQALQTGCTLQEVAEKVSFSHCIPRTFAKQISKDSFLTKIRMRRVFAEFVRKFQHTV
DKGQLGAHEIMYKYISTLEHLAPRFGTETFPVSHLELREDGDESSSYSNTTHAEGASKDN
FRMPATHEIMVSGTKGIQWRKVSAQKAQANSYLRNDYMNYMKKTKQQSSQPNANTPNKWT
SFCDFPEITHIAITGDTVCISTQDSHCMEVQMNSSQEARSFISLLDGYNRLTAFAHHYLC
HEVAPPRVVLSVANGLHGPMHDDFVLLKLKKEAAEEGAFLVRWSAVDYHRIILAVLSKNG
NGSKPSHKQFRIHHKGSMFSLEGWDREFPSMKELAESLKTYVLKSGPDSFTVKKCCLPKQ
AELSNLLVMRQGAHTDSLSLNMAQVRFHQIKEKDIIQEQHLGRGTRTNIYSGRLLVRGGE
HEDDDEFNNNSADRKGIQVVLKILDQSDKDTDIGFLETASLMSQVSHRHLVFVHGMSVKG
SENIMVEEFVEFGPLDVFLRREKASVTPQWKFIVAKQLASALNYLETKWLVHGNVCARNI
LVARRGLEQGTTPFVKLSDPGIALSVLSREERLERIPWIAPECVESGASIGNAADQWSFG
ITLLEICNNGDLPMSGSTLSEKERFFQQKGRLAEPSSQELASFISMCLTYEPVERPSFRT
VLRELTEIMIKNPDISPSETLPDTDPSIFHKRYLKKMRDLGEGHFGKVTLYLYDPTNDGT
GERVAVKALKQENGHVPEGWMKEIEILKSLYHCNIVKYKGCCTELGGQVVQLIMEYLPLG
SLREYLPKRKLGMQQCLMFAQQICQGMEYLHSKRYIHRDLAARNVLVENDNLVKIGDFGL
TKYIPEGEIYYRVREDGDSPVFWYAIECLKESKFSFSSDIWSFGVTLYEILTRCEHRQSP
PIKFFEMMEATQGQMTVMVLIKLLEKQLRLPRPKDCPHEVKLLMEQCWATEPAQRPSFSD
LIEKFEAIRQAYNWQSNINFSLAQIC
NT seq
3501 nt
NT seq
+upstream
nt +downstream
nt
atgtccagaagtgggtggtccaagcgttctaggcaaggggcattcccaggcctgcccgac
ccccctcagggtccgggcatccatgtctacttgttctgctcaaaggaaggtgaaagatat
ttgtctcacacaaacggaggagtcacagcagaggacttgtgcatctcagcggcagaggca
gtagggataactcctctgtgccatgtattgtttgcgctgtacaacccgcagtcacggtgc
tggtacagtccaaaccatgacttcaatccagacaactccagcctcgttcttcactactgc
atgaggttttactttcggaattggcacgggctgaatcagaaggagccagctgtgtctcga
tattctctcagatctgggacaaatcagggcggctccccactgcttgaaatcgcatcctta
caatacttattctcccaggctaaatatgagtttgtgaacgaagtaatacagatggaagac
cttcagtcggcggaggatataagtcgcttcaaaaatgaaagcttggggatggccgtgctt
caactctctcaccaggcattgcaaacaggttgcaccttacaagaggttgctgaaaaagtc
agcttctcacactgcataccgaggacttttgccaaacagatttccaaagacagcttcctg
acaaaaatcaggatgcggcgggtgtttgcagagtttgtgcggaaattccagcacaccgtg
gacaagggacaactaggcgcccatgagatcatgtataagtacatctctactcttgaacac
ttggcaccacgttttggtacggagaccttcccagtatcccacctggaactaagagaggac
ggggatgaaagcagctcttactccaacaccacccacgcagagggtgcctcgaaagataac
ttcagaatgcctgccacacatgagataatggtgtctggcaccaagggtattcagtggaga
aaggtgtccgctcagaaggcgcaggcaaacagttacctcaggaacgactacatgaactac
atgaagaaaacaaaacaacagtccagccaaccgaatgcaaacactcctaataaatggacc
tccttctgtgatttccctgaaataactcacatagccatcaccggagatactgtgtgcatt
agcactcaggacagtcactgcatggaggttcagatgaactccagccaggaggcccgttcc
ttcatctccctcctagatggatacaaccgactgactgcgttcgcccaccactatctttgt
catgaagtggctcccccaagggtagtgctgagtgtagcaaatggactgcatggacctatg
catgatgattttgtgctgctgaagctgaaaaaggaagcagcagaggagggagctttcctc
gtacgttggagtgctgtggactatcaccgcatcatcctggctgtcctgagcaaaaatggg
aatggatcaaagccgagccacaagcagtttcggatacaccacaagggttcgatgttctct
ctggagggatgggaccgagaattccccagcatgaaggagctcgcagaaagcctcaagacc
tatgtcctcaagtctggtccagacagttttactgtcaaaaaatgctgtttgccaaaacaa
gcagagctatccaaccttctggtgatgaggcagggtgctcacacagactccttgtcccta
aacatggcccaagtacgctttcaccagatcaaggaaaaagacatcatacaggaacagcat
ctgggccgcggaaccagaacaaacatctactcgggacgtctgctggtgcgtggtggagaa
catgaggatgatgacgagttcaacaacaactccgctgaccgcaaagggatccaagtggtt
ctcaagattctagaccaaagtgataaagatactgatataggatttttggaaaccgcaagt
ctcatgagccaggtgtcccacaggcacctggtgtttgtacatggcatgtcagtcaaagga
tctgaaaacatcatggtggaagaatttgtggagtttgggcctttggatgttttccttcgc
agagaaaaggcctcagtgacacctcagtggaaattcattgttgcaaaacaacttgcaagt
gccctcaattatcttgagactaaatggctggttcatggaaacgtctgtgccaggaacatt
ctggtggcgaggcgtggtctggagcaaggcactactccttttgtcaagctgagcgaccca
gggatcgccctgagcgtcctttcacgcgaagagcgtcttgagcgcatcccgtggattgcc
cctgagtgtgttgaaagcggtgcatccattggcaacgctgctgaccagtggagctttggc
atcaccctgcttgaaatctgcaacaatggcgatcttcccatgagtggcagcacgctgtct
gaaaaagagcgcttttttcagcaaaagggccgtttagctgagccatcctcacaggagctg
gccagtttcatcagcatgtgtttgacctacgagcccgtggagaggccttcgttccgcact
gtgctcagagagctcaccgaaatcatgatcaagaatcctgatatatcccccagcgaaact
ctacctgacacagaccctagcatattccataaacggtacctgaaaaagatgcgggactta
ggagagggacactttgggaaggtgactctctacttgtatgacccgaccaacgatgggaca
ggagaacgtgtggcagtgaaggctttgaaacaggaaaacggtcatgtgcctgagggctgg
atgaaggagattgagatcctgaagtccctctatcactgcaacattgtcaagtacaagggc
tgttgtactgagctgggaggacaagtggtgcagctgataatggagtaccttcccctgggg
agtctgcgagagtaccttcccaaacgtaaactgggaatgcagcagtgccttatgtttgct
cagcagatctgtcagggtatggagtacttgcactcgaagcgatacatccatcgagacctg
gccgcccgtaatgttctagtggaaaatgacaatttggtaaagattggagactttggcctg
accaaatacatccctgaaggcgagatctactatcgtgtccgtgaggacggggacagtcca
gtgttctggtatgccattgagtgcttgaaggagagcaagttttccttttcctctgacatt
tggtccttcggcgttacattgtatgagatcctgacccgctgtgaacatcgccaaagccct
ccgataaagttctttgaaatgatggaggcaacccagggacagatgactgtgatggtactc
ataaaactgctggagaaacagctgcgattacctcgtcccaaagactgcccgcatgaggtg
aagctgttaatggagcagtgctgggctacagagccggcacagcggccatcattcagcgac
ctcatcgaaaagtttgaggctattcgccaagcatacaactggcagtctaatataaacttt
tccttggctcagatttgctga
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