KEGG   Epinephelus fuscoguttatus (brown-marbled grouper): 125880367
Entry
125880367         CDS       T08419                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
efo  Epinephelus fuscoguttatus (brown-marbled grouper)
Pathway
efo04010  MAPK signaling pathway
efo04012  ErbB signaling pathway
efo04020  Calcium signaling pathway
efo04510  Focal adhesion
efo04520  Adherens junction
efo04530  Tight junction
Brite
KEGG Orthology (KO) [BR:efo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125880367 (erbb2)
   04012 ErbB signaling pathway
    125880367 (erbb2)
   04020 Calcium signaling pathway
    125880367 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    125880367 (erbb2)
   04520 Adherens junction
    125880367 (erbb2)
   04530 Tight junction
    125880367 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efo01001]
    125880367 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:efo04147]
    125880367 (erbb2)
   04090 CD molecules [BR:efo04090]
    125880367 (erbb2)
Enzymes [BR:efo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     125880367 (erbb2)
Protein kinases [BR:efo01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   125880367 (erbb2)
Exosome [BR:efo04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   125880367 (erbb2)
CD molecules [BR:efo04090]
 Proteins
  125880367 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Tcell_CD4_C Haspin_kinase
Other DBs
NCBI-GeneID: 125880367
NCBI-ProteinID: XP_049418691
LinkDB
Position
LG20:19017480..19054583
AA seq 1299 aa
MEAARSLVFVGAVLLGVTGALAREVCLGTDMKLALPSSLENHYETLKLLYTGCQVVHGNL
EITHLHGNPDLSFLQGIVEVQGYVLVAHVSVSLLPLDNLRIIRGSQLYNSSYALAVLENT
QGGQGLRTLRLRSLTEILLGAVYIWGNPQLCFPDPQNIVWRDTLDEKNIDARLHRLQPRA
PKCPSCSPACGESCWGETAQDCQTLTRIKCASGCQRCKGPLPSDCCHMQCAAGCTGPKDS
DCLACRHFNDSGVCKESCPPPTIYDTVTFQTKSNPNKKFNFGATCVKTCPYNYLAMEVAC
TLVCPGANQEVVISSPDGNETQKCEKCEGDCPKVCYGLGMDNLGVMENHGVTMVTSSNVE
KFNKCKKIFGSLAFLPQSFVRDPASNTSGLTLEQLSSFKNLEEITGYLYIDAWPEEWTNL
SVFENLKVIRGRMLYKGVFSLAIQNLHIRSLGLRSLRSVSGGLVLLHNNSQLCYTNSLPW
DNLLHPTQGPHRIVSQNQDAQRCEDEGRVCHPLCEGGCWGPGPSQCVSCTAFQRGTECVE
QCDIYQGSVREYTDGSLCVACHAECRAINGSASCHGPGAEHCSECRNFQDGEFCVDHCPS
GVKEDQQTVWKYSNATRHCLPCHTNCTLSCTVMDDRGCPIDTRTGPGTTIAAAVGGVVLF
FILLALLIFYLRRQKKLKRKETMRRILQEHELVEPLTPSGASPNQAQMRILKETELKKLR
VLGAGAFGTVYKGVWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCR
LLGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEEVRLVHR
DLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSD
VWSYGVTVWELMTFGAKPYDMIPAREIPDVLEGGERLPQPLICTIDVYMIMVKCWMIDPD
SRPRFRDLVNDFSTMARDPPRYVVIQNDEQMSMSSPVDSQFFRMLLEEEGNNMRELLDAE
EYLVPQPNLFPRTQGDGVQANGPSRHQSYRQSRDQGLNVEPSVAGGPRSMYSSLSTLGRS
QYPTLPLGASTSNGIWIPQYPTLARSTSAGGQSDSVFLDGPPDDPTLPPASPGRYSKDPT
YSNGSQGDLETDGPNGFHHPPLLHHSLPRRTHGYNHNHPLPEYVNQEIQDLRPGIPDRPS
TLPRKGARVDRRLPNGLSSGHSVENPGYLVPVGAVSATSPAFDNPYYLDLVAKANTVAEV
ADSPEMRDGGVPKHVNGFVTPTAENPEYLGLADTWSGYT
NT seq 3900 nt   +upstreamnt  +downstreamnt
atggaggcggcgagaagtttggtgtttgtcggggccgtgctgctcggagtgacgggcgcg
ttggccagagaagtatgcctgggtacagacatgaagctggccctgccctccagcctggaa
aatcactacgagaccctgaagctgctctacaccggctgccaggttgtccacggcaacctg
gagatcacacatcttcatggaaaccctgacctatccttcctacaggggatcgtggaggta
cagggctatgtacttgtagcccatgtgtcagtgagtctgttgcctttggacaaccttcgg
atcataagaggcagccagctgtacaactccagctacgccctggctgtgctagaaaacact
cagggtggacaggggctcaggacactccggcttcgtagcctcacagagatcctgttgggt
gcggtatatatttgggggaacccccagctgtgcttcccagacccccagaacatcgtctgg
agggacactttggacgaaaagaacatcgacgccaggctgcaccgactgcagcctcgggcc
cctaaatgtccaagttgttcgcctgcatgtggggaaagctgctggggagaaactgcacag
gactgccagaccttgacccgtattaaatgtgcatctggctgtcagcggtgtaaaggtccc
cttcccagtgactgctgtcacatgcagtgtgctgctggatgcacaggacccaaagactca
gactgtctggcttgccgccacttcaacgacagcggtgtgtgtaaggagagctgtcctcct
cccactatctacgacactgtcaccttccagaccaaatccaacccaaacaagaagtttaac
tttggtgccacctgtgtcaagacatgtccttataactatctggctatggaagtggcttgt
actttggtttgtcccggggccaaccaggaagttgtcatcagcagccccgatggaaacgag
acgcagaaatgtgaaaagtgcgaaggagactgtcccaaagtgtgttatggtctgggcatg
gacaacctcggcgtcatggaaaaccacggtgtcaccatggtaacatcttccaacgtggag
aagttcaacaagtgtaagaagatttttggcagtctggcctttctccctcagagctttgta
agggaccctgcgagtaacacatcaggcctgaccctggagcagctgagctccttcaagaat
ctggaggagattacaggctatttgtatattgatgcctggccagaagagtggactaacctg
agtgtgtttgagaacctgaaggtgatcagaggcaggatgctctacaagggtgtgttttca
ctggccatccagaatctacacatccggtctcttgggttgcgttcactgcgcagcgtcagt
ggaggtttggtcctgttgcacaacaactcccagctgtgctacaccaattctctgccttgg
gacaatctcctccatcccacccagggaccccaccgcatcgtcagccagaaccaggatgcc
cagcgctgtgaggatgaggggcgtgtgtgtcacccactgtgtgaggggggctgctggggc
ccagggcccagccagtgtgtgtcctgcacggctttccaacgcggcactgagtgtgtagag
cagtgtgacatctatcaggggtctgtccgtgaatacacagacggatctttgtgtgttgcc
tgtcacgcagagtgtcgagctatcaacggctctgcctcctgtcacggaccgggtgctgaa
cactgttcagagtgtcgaaacttccaggatggtgagttctgtgtggatcattgtcccagc
ggtgtcaaggaggatcagcagaccgtatggaagtacagcaacgccacaagacactgtctg
ccctgccacaccaactgcacgctgtcctgcaccgtgatggacgacagaggctgccccatc
gacaccaggacaggaccgggtacaaccatcgcagctgcagtgggtggggtcgtgctcttc
ttcatcctgctggctctgctgatcttctacctgaggagacagaagaagctgaagaggaag
gagacgatgaggaggatcctgcaagaacatgagctggtggagcctctaacacccagcggc
gcgtcacccaatcaggctcagatgcgtatcctgaaggagactgagcttaaaaaactcagg
gtgctgggtgcaggggcctttgggactgtttacaagggagtgtgggctcctgatggagaa
aatgtgaaaataccagtggccatcaaggtgttacgagagaacacctcgccaaaggccaac
aaagagatccttgatgaggcctatgtgatggcaggtgtggccagcccctacgtctgccgg
ctgctcgggatttgtctgacctccacagtgcagctggtcactcagctgatgccgtacggc
tgcctcctcgactacgtcagggagaacaaggaccgcatcggctcccagttcctcctcaac
tggtgtgtccagatcgccaaggggatgagttatttagaggaggtccggctggttcacaga
gatttggccgcccgcaatgttctggtcaaaaacccgaatcatgtgaagatcaccgatttt
ggtctggcccgtctgctcgatatagacgagactgaatatcacgctgatggagggaaggtg
ccaattaaatggatggctttggagtctattctgcacagaaagttcactcatcagagtgac
gtctggagctacggtgtgacggtctgggagctgatgacgttcggtgctaaaccctacgac
atgatcccagccagagaaatcccagatgttttagaaggaggagagcgacttccccagccg
ctcatctgcaccatcgacgtctacatgatcatggtcaaatgttggatgattgacccagac
agcaggccgaggttcagagatctggtgaatgattttagcacgatggccagagatccacct
cgctatgtagtcattcagaacgacgagcagatgagcatgtccagcccagtggacagccag
ttcttccgaatgcttctggaggaggaaggaaacaacatgagggagctgctggatgctgag
gagtatctggtgcctcagccaaacctcttccccaggactcagggagacggggtacaagcc
aacgggccatccagacaccagtcatacaggcagagcagagatcagggcttaaatgtggag
ccctctgttgccggcggccctcggagcatgtactcctccctgagcactcttggccgcagc
cagtaccctaccttacctttaggagccagcacctccaacggcatatggattcctcagtac
ccaacgctggctcgcagcacctcggccgggggccagtctgactctgtcttcctggatggg
cctccagatgaccccacgctgcccccggccagccccggacgctacagcaaagaccccaca
tactccaacgggagccagggcgacttggagacagatgggccaaatggcttccatcatcct
cctctccttcatcactcactgcccagacggactcatgggtataatcataatcatcccttg
ccagagtatgtcaaccaggagattcaggatctcaggccggggatcccagatcggcccagc
actttgcctcgtaaaggcgccagagtagaccggcgcctccctaatggcctgagctctggt
cacagcgtggaaaacccgggctacttggtccccgtgggtgcagtgtccgccacctctccg
gcctttgataacccgtactacctggacctcgtagccaaagctaacactgtagccgaggtt
gcagacagtcctgagatgagagacggaggagtgcccaagcacgtgaatgggtttgtaacc
cccacggcagagaatccagagtatctgggactagcggacacctggagtggatatacttga

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