Epinephelus fuscoguttatus (brown-marbled grouper): 125903702
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Entry
125903702 CDS
T08419
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
efo
Epinephelus fuscoguttatus (brown-marbled grouper)
Pathway
efo00270
Cysteine and methionine metabolism
efo00480
Glutathione metabolism
efo01100
Metabolic pathways
efo01240
Biosynthesis of cofactors
efo04216
Ferroptosis
Module
efo_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
efo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
125903702 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
125903702 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
125903702 (gclc)
Enzymes [BR:
efo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
125903702 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
125903702
NCBI-ProteinID:
XP_049456749
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Position
LG16:complement(23055378..23068804)
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AA seq
630 aa
AA seq
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MGLLSQGSPLNWEETKKYADHIRKHGIIQFLNIYNKVKERQKDVLKWGDEVEYMLVELDD
KDEKVRLVLNGGDVLKTLQDQGELINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMGKRRREASSVLNQNETLCTITSFPRLGCPGFTKPEYPPTPVEEGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIFKDKCTPSPFVEEFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGLVSDNDCRWGV
ISASVDDRTQEERGLKPLKNNKYRIFKSRYDSIDSYLSSCGEKYNDIDLTIDEEIYKQLL
DAGIDKLLAQHIAHLFIRDPLSVFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
QEGMFYFRKDIFKGCNPGLDGTASAQNGLETDSGNEEYTLMSIDTIINGKDGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAKHPQYKQDSVLTDKI
NYDLFKKCDKIAKGEEQCPELIGNPVNRFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtttactgtcacaggggtctccgctcaactgggaagaaaccaagaagtatgcggac
cacatcaggaagcacggcatcatccagttcctcaacatctacaacaaggtgaaggagagg
cagaaagatgtgctcaagtggggcgatgaggtggagtacatgttggtggaattggatgac
aaggatgaaaaggttcggcttgtgctgaacggcggagatgttttgaaaactctccaagac
cagggtgaattgataaaccccaaccaccccacactgtggagaccagagtatggcagctac
atgattgaaggtactccagggcagccgtatggcgggacgatgtcggagttcaacactgtt
gagggcaacatggggaagagacgacgagaggcctcgtctgtcctgaaccagaatgaaacc
ctctgcaccatcacctcatttccaaggttaggttgcccaggtttcaccaaaccagagtac
ccgccgacccccgttgaagagggagtgtcaaagtcactgtttttcccagatgaagccatc
aacagacatccgagattcagcacccttaccagaaacatacgtcacagaagaggagagaaa
gtcgtgattaatgtgccaatcttcaaagataagtgcaccccatctccatttgtggaggag
tttcctgaggatgacggtgaagcagcgagggcggctctgcccgatcacatctacatggac
gccatgggcttcggcatgggcaactgctgtctgcaggtgacattccaggcttgtagcatc
gatgaggcaagatacctttacgaccaactagcaacattctgccccatagtgatggcattg
agtgcggcctcccccttctacagaggccttgtgtcagataacgattgtcgctggggagtt
atttctgcctctgtggacgacaggacacaggaggaacgcgggctcaagcctttgaaaaac
aacaaatacaggatcttcaagtcaagatatgactcaattgacagctacctgtccagctgt
ggcgagaagtacaatgacatcgatctgacgatagatgaggagatctacaagcagctgctc
gacgcaggaattgacaagctgctggctcaacatatagcacacctcttcatccgagatccg
ctctccgtctttgaggagaaaattcacttggatgatgaaaacgagtcagatcactttgag
aacctccagtcgactaactggcagacgatgaggttcaaacctccgcctccgaactcagat
attggctggagagttgagttccgccccatggaggtgcagctaactgactttgaaaatgct
gcatacgtggtctttgttgtcctgctcaccagagtgatcctgtcctacaaactggacttc
ctgatccctctgtcaaaggtcgatgaaaacatgaaggtcgcacagaagagaaacgctgtc
caggagggcatgttttacttccgaaaggatatcttcaaaggctgcaacccaggactcgat
ggaacagcgtcagctcagaacggcttggagactgacagtggtaacgaggagtacacgctg
atgagcatcgacacaatcatcaacggaaaggacggagtattccaaggccttatcccgatc
cttaactgttacctggaaaacatggaggtagatgtggacaccagatgcaccattttaaac
tatctgaagctcatcaagaaacgtgcctcaggtgaactgatgaccatggccaagtggatg
agggaatttgttgccaagcacccacagtataagcaggacagcgtcctaactgacaagatc
aactacgaccttttcaagaagtgcgacaagattgcgaaaggcgaagagcagtgcccggag
ctcattggaaacccagtgaacaggttcaaatga
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