Enterococcus faecalis Symbioflor 1: EFS1_0672
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Entry
EFS1_0672 CDS
T02399
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
efs
Enterococcus faecalis Symbioflor 1
Pathway
efs00300
Lysine biosynthesis
efs00550
Peptidoglycan biosynthesis
efs01100
Metabolic pathways
efs01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
efs00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EFS1_0672 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EFS1_0672 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EFS1_0672 (murF)
Enzymes [BR:
efs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EFS1_0672 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Thr_synth_N
MoCF_biosynth
RecA-like_ORC2
HgmA_C
Motif
Other DBs
NCBI-ProteinID:
CCO71750
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All DBs
Position
686306..687679
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AA seq
457 aa
AA seq
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MKLTFWEVAQAVEASNDWQQWPDFPLTGIEFDSRKIVKGNLFVPLQGENDGHRFIESAMA
NGCQAAFWGQDLVDAPQQLPVLHVTDPLVAMQKLATYYLNKMQPNVIAVTGSNGKTTTKD
LIAAVLSEKFVTYKTQGNYNNQIGLPYTILHMPDETEKLILEMGMDHAQEISFLSNLAQP
EVAAITMIGEAHVENLGSRAGIAQAKMEIVDGLAKDGSLFVPSDEPLLEPLVEKVTQQVI
TFGFSQESQLQGIVTNEAKEQTSFKISDTQMTFTIPVPGTYNVTNALIAIGIGRYFQLTD
SEIQKGLATAELTKNRTEWLKAANGAEILSDVYNANPTAMGLVLDSFSKMSKVGKRIAVL
GDMLELGPDSASMHQAMAQHLAPDAIEEVFLYGSEMAYLADKLQETYAPANIHSFKKEEK
NELIEAVKKVLQPEDMVVLKGSNGMGLREVIDALLEK
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaaccttctgggaagtagcgcaagcggttgaagccagtaatgattggcaacaa
tggcctgattttcctttaacaggcattgaatttgatagtcgtaaaattgtgaaaggaaat
ctctttgttcctttacaaggtgaaaatgatggtcatcgttttattgagagtgccatggct
aatggctgtcaggccgctttttggggacaggatttagtcgatgcgccgcaacaattgcct
gttttgcatgttactgatccactggttgctatgcaaaaattagctacctattatttaaat
aaaatgcaaccgaatgtcatcgctgtgactggcagtaatggaaaaactaccactaaagat
ttgattgctgctgtgttatctgaaaagtttgtgacttacaaaacgcaaggcaattacaat
aatcaaattggcttaccctatactattttacacatgcctgatgaaacagaaaaactgatt
ttagaaatgggcatggatcatgctcaggaaatttctttcctttccaatctggctcagcca
gaagttgctgccatcacaatgattggcgaagcccatgtggaaaatttaggctcacgagca
ggcattgcacaagcaaaaatggaaatcgtagatggtttagccaaagacggtagtttattt
gtgccaagcgatgaacctttgctagaaccattggtggaaaaagtcacgcaacaagtgatt
acttttggttttagccaggaaagtcaacttcaaggaatcgtcacaaatgaagccaaagag
caaacctcattcaaaatcagtgatacacaaatgacgtttacgattccagtgccaggaacc
tataatgtcaccaatgcattaatcgcaattggtattggtcggtatttccaattaacggat
agtgagattcaaaaagggttggctacagcggaactaacaaagaatcggacagaatggctg
aaagcagcgaatggtgccgaaattttaagtgacgtgtacaatgccaatccgacagctatg
ggtcttgttctggacagttttagcaaaatgtccaaagtaggaaaacgaattgctgtttta
ggagacatgctggaattaggtcctgattctgctagcatgcatcaagcaatggcgcagcat
ttagccccagatgcgattgaagaagtctttttatatggttctgaaatggcttatttagct
gataaattgcaagaaacctatgcaccagctaacattcattcttttaaaaaagaagaaaaa
aatgagttgattgaagctgtcaaaaaagtcttacagccagaagatatggtggttttaaag
ggaagtaacgggatgggacttcgtgaagtcatcgatgcacttttggaaaagtaa
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