Enterococcus faecium T110: M395_01005
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Entry
M395_01005 CDS
T03257
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
eft
Enterococcus faecium T110
Pathway
eft00300
Lysine biosynthesis
eft00550
Peptidoglycan biosynthesis
eft01100
Metabolic pathways
eft01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
eft00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
M395_01005
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
M395_01005
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
M395_01005
Enzymes [BR:
eft01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
M395_01005
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3323
Motif
Other DBs
NCBI-ProteinID:
AII40162
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All DBs
Position
194244..195656
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AA seq
470 aa
AA seq
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MRTRRLGQTLFSQPFLGEISMNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVP
LAGTRDGHEFIQQAITNGASASFWSLPVEQAPKDIPVIPVADPLKAMQQLANYYLEKVGA
EVVAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVPDGLLVVPAD
EPLLTPLTATLVQTVTTFGIGNGDVHAEVTAEGKAQTDFVVEGETFTIPLPGSYNVTNAL
IAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMGLVLDTF
KNLPTKGRRIAVLADMLELGKDSLNMHAQMSEHIDPEKFAMIFLYGEQMHALKEDLNQKY
PQLPVFYFEKEKNKLIEAVKQNLESTDSIMLKGSNSMGLFEVVEQLQQMK
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgcgaacccgccgtttaggccaaacgcttttttcacaaccttttttaggagagatctca
atgaatctaacaatacaagaaattgcacaagccgtgggcagcgaatgctctgcactgaca
aagattaccaatgtcgaatttgacagccggaagataaccgaaggaagtttattcgttcct
cttgccggtacgagagatggacatgaatttatccagcaagcgatcacaaacggagcatct
gcttcattttggagcttgcctgttgaacaagcaccaaaagatattccagttattcctgta
gcagatcctttgaaagccatgcagcaattggcaaactattacttggaaaaagtaggcgca
gaagtcgttgcaattacaggaagcaatggtaaaaccaccacgaaagatctaaccgcgtct
gtcttgtctgaaaaatacaaaacatataagacgcaaggaaattacaacaataatattggt
cttccttacacgattttgcacatgccccaagatacagaaaagatcgttttggaaatgggc
atggatcacgccaatgaaatcacggaactttcacttatggctcaaccaaaagctgcagca
atcacaatgatcggtgaagcgcacatagaaaatcttgggtcgcgagaaggaatcgctaaa
gccaaaatggaaatcactgacggacttgtaccagacggattactcgttgtgcccgcagat
gaaccgttgctgacacctttaacggcaacattagtacaaacagtcacaacattcggtatt
ggaaatggcgatgttcatgcggaagtgacagcagaaggaaaagcacaaaccgattttgta
gtagaaggagaaacatttacgatcccgctgcctggaagttataatgtaacgaatgctttg
attgcgtatacgatcgggcgcttctttggactgtccatacctgagatacgccaagggctc
gctcatgtttctatcactcaaaacagaactgaatggctaacggcaggaaatggtgcagct
attttgagcgatgtctacaatgcaaatccaacagccatgggactggtattagatactttt
aaaaatctgccaacaaaaggacgcagaatcgctgtgttagcagatatgctggaattaggg
aaagattcattaaacatgcatgcgcaaatgagtgaacatatcgatcctgagaaatttgcc
atgattttcttgtacggggaacaaatgcatgcattaaaagaagacttgaatcaaaaatat
ccgcaactgcctgtgttctattttgaaaaagaaaagaataaattgattgaggctgtcaaa
caaaatcttgaatccacagacagcattatgctgaaaggcagcaatagcatgggcttattc
gaagtagtagaacagcttcagcaaatgaaataa
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