Enterococcus faecium DO: HMPREF0351_12184
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Entry
HMPREF0351_12184 CDS
T02120
Symbol
folC
Name
(GenBank) tetrahydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
efu
Enterococcus faecium DO
Pathway
efu00790
Folate biosynthesis
efu01100
Metabolic pathways
efu01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
efu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HMPREF0351_12184 (folC)
Enzymes [BR:
efu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HMPREF0351_12184 (folC)
6.3.2.17 tetrahydrofolate synthase
HMPREF0351_12184 (folC)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Ribosomal_60s
Motif
Other DBs
NCBI-ProteinID:
AFK59808
UniProt:
I3U470
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All DBs
Position
complement(2124963..2126291)
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AA seq
442 aa
AA seq
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MGELLMTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHIAGTNGKGSTVA
YLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKYQPLIKQLDQFEAV
AGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPMLTGITTIGLDHTEILG
DTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAPLYVYGENYKINYLHPDE
MWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVYCQLEKLPFREKDVLKGLKK
SRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFKGYQINILFSALRTKNVREMLE
RLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIVSLWQFGLADILEKMTNEDVLVVT
GSLYFISEVRHLLIQLGGDHEV
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgggggaattgttgatgacgattgaagaagcaatagaatggatccatagtcgattacca
tttggttcacgtcctggccttgaccgagtcgaagctttattagaagtggtagggcatcca
gagagaaaagtaaaaacgatccatatcgctggaacaaacggaaaaggttctactgtagct
tatttgagaagcctattagaagaggctgggctgacagtaggtacatttacttcaccttat
atcgaaacgttcaatgaacggatcgcaatcaatggcaaaagcattccagacaatgatttg
atccagcttgtaaaaaaatatcagccactgatcaaacaacttgatcaatttgaagcagta
gctggtattactgaattcgagacattaacagcaatggcatttgattattttttgatgaag
aaagtggacgtagcgattatcgaagttggcttaggcggcttattggattctaccaatgta
gctgtaccaatgctgacgggaataacaacgattggacttgatcataccgaaatacttgga
gatacaattgaagaaatcgctgcacaaaaagctggaatcatcaaacaaggcgttccagta
gtaacaggaaatattgccccagaagcttttactgtcatccaacaaacagctaaagcaaaa
aatgcaccgctttatgtatacggggaaaattataaaataaactatctgcatcctgatgag
atgtggggagaagtatttgaattttttaatgaaataggaaagatccctcaattaaccact
ccgcttttagggcaacatcaagctgaaaatgcaggagtagccatcgaattgtattttgtt
tactgtcaattggaaaagctgcctttccgagaaaaagatgttttgaagggattgaagaaa
tctcgatggccaggaagaatggagcgtttgagtaacgagccattagttgttttagatggt
gcccataatacgcatgcaatgaaccggcttgttgagaatttgaaaaaagaattcaaagga
tatcaaatcaacattttgttttccgccttacgaactaaaaatgttagagaaatgctagaa
cgattgcagcaagtaccaaatgtccatatttatttgacgacctttgaacatccaaaagcc
atcgaattaagtgaagtatcagatttagcaagtgagagagtatcaatcgtttcattgtgg
caattcggattagcagatatattggaaaagatgacaaatgaagacgtattagttgtgacc
ggttcactttatttcatttcagaagttcgccatttattaatacaattaggaggagatcat
gaagtataa
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