Eptesicus fuscus (big brown bat): 103283327
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Entry
103283327 CDS
T09083
Symbol
GAD1
Name
(RefSeq) glutamate decarboxylase 1 isoform X1
KO
K01580
glutamate decarboxylase [EC:
4.1.1.15
]
Organism
efus
Eptesicus fuscus (big brown bat)
Pathway
efus00250
Alanine, aspartate and glutamate metabolism
efus00410
beta-Alanine metabolism
efus00430
Taurine and hypotaurine metabolism
efus00650
Butanoate metabolism
efus01100
Metabolic pathways
efus04727
GABAergic synapse
efus04940
Type I diabetes mellitus
Module
efus_M00027
GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:
efus00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
103283327 (GAD1)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
103283327 (GAD1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
103283327 (GAD1)
00430 Taurine and hypotaurine metabolism
103283327 (GAD1)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
103283327 (GAD1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
103283327 (GAD1)
Enzymes [BR:
efus01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.15 glutamate decarboxylase
103283327 (GAD1)
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GFIT
Motif
Pfam:
Pyridoxal_deC
Aminotran_5
Beta_elim_lyase
DegT_DnrJ_EryC1
SepSecS
OKR_DC_1
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
103283327
NCBI-ProteinID:
XP_027996804
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Position
11:47753477..47795473
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AA seq
594 aa
AA seq
DB search
MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTKKLGLKICGFLQRTNSLEEK
SRLVSAFKDRQASKNLISCENSDRDGHFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDQPESLEQILVDCRDTLKYGV
RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWS
NKDGDGIFSPGGAISNMYSIMAARYKFFPEVKTKGMAAVPNLVLFTSEHSHYSIKKAGAA
LGFGTDNVILIKCNERGKIIPADLEAKILEAKQKGYVPLYVNATAGTTVYGAFDPIQEIA
DICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERASSVTWNPHKMMGVLLQCSAILVKE
KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI
NKCLELAEYLYAKIKNRDEFEMVFSGEPEHTNVCFWYIPQSLRSMPDSPERRERLHKVAP
KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
NT seq
1785 nt
NT seq
+upstream
nt +downstream
nt
atggcgtcttcgaccccttcttcatcggctacctcctccaacgccggagcggaccccaat
actaccaacctgcgtcccacaacgtatgacacctggtgtggcgtggcccacggatgcacc
aaaaaactggggctcaagatctgcggcttcttgcaaaggaccaacagcctggaagagaag
agccggcttgtgagcgccttcaaggacaggcaggcctccaagaacctgatttcctgcgag
aacagcgacagggatggccacttcaggcgcacggagaccgatttctccaacctgtttgct
cgagatctgcttccagctaagaatggggaggagcaaactgtgcaattcctactggaggtg
gtggacatactcctcaactatgtccgtaagacatttgatcgctccaccaaggtgctggac
ttccatcacccacaccagctgctggaaggcatggagggcttcaacttggagctctctgac
caacctgagtccctggagcagattctggttgactgcagagacaccctgaagtacggggtc
cgcacaggtcatcctcgatttttcaatcagctctccactggactggatatcattggatta
gctggtgaatggctgacatcaactgccaataccaatatgtttacttatgaaattgctcca
gtgtttgtcctcatggagcaaataacgcttaagaagatgagagagatagttggatggtca
aataaagatggtgatgggatattttctcctgggggagccatatccaacatgtacagcatc
atggcagcgcgatacaagttcttcccagaagttaagacaaagggcatggcagccgtgccc
aacctggtcctcttcacctcagaacatagtcactactccataaaaaaggctggggctgca
cttggctttggaaccgacaacgtgattttgataaagtgcaatgaaagggggaagataatt
cctgctgatttagaggcaaaaattcttgaagccaagcaaaagggatatgttcctctttat
gtcaatgcaactgctggcacgactgtttatggagcctttgatccgatacaggagattgca
gatatatgtgagaaatataacctttggctgcatgtcgatgctgcctggggcggtgggctg
ctcatgtccaggaagcaccgtcataaactcagtggcatagaaagggccagctcggtgacc
tggaacccgcacaagatgatgggcgtgctgctgcagtgctccgccattctcgtcaaggag
aaggggatactccaaggatgcaaccagatgtgtgccggctacctcttccagccagacaag
caatatgatgtctcctatgacactggggacaaggcaattcagtgtggccgtcacgtggac
attttcaagttctggctgatgtggaaagccaagggaacagtgggatttgaaaaccagatc
aacaagtgcttggaactggctgaatacctctatgccaaaattaaaaacagagacgaattt
gagatggttttcagtggtgagcctgagcacacaaatgtctgtttctggtacattccacaa
agcctccggagcatgcccgacagccctgagcgacgggaaagactccacaaggtggctccc
aaaatcaaagccctgatgatggagtctggcacgaccatggttggctaccagcctcagggg
gacaaggccaacttcttccggatggtcatctcgaacccggccgccacgcagtctgacatc
gacttcctcattgaggagatagagagactgggccaggacctgtaa
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